iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036906

Ensembl Protein ID

ENSFALP00000000413.1

UniProt Accession

U3JCA9; U3JCA9_FICAL

Genbank Protein ID

ENSFALP00000000413

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000399

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000000395.1	ENSFALT00000000416.1	ENSFALP00000000413.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	53.97	6.00e-136	482.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

RMSFPNSSQH PGAGNSCRIT LGQANQVIPK VPLLRILQAA GAQGDTFTLK EVMHFLGQYI 60
MGRQLYDKRQ QHLVHCGGDQ LGELLGLITK GIFLSLPSPV YEMLKRNLSP AALPAADAAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATGAGCT TCCCAAATTC CAGCCAACAT CCAGGAGCTG GGAATTCCTG CAGGATCACC 60
CTTGGACAAG CCAATCAGGT AATTGCCCCC CCCCCCCCCC CCCCCCCTCT TTTTTTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	54.27	3.00e-132	464.00
IUUC-Apl-003800	Anas platyrhynchos	73.54	0.00e+00	637.00
IUUC-Aca-004608	Anolis carolinensis	52.89	2.00e-126	445.00
IUUC-Ame-010869	Astyanax mexicanus	44.51	1.00e-98	353.00
IUUC-Bta-013287	Bos taurus	53.56	3.00e-142	498.00
IUUC-Cja-019305	Callithrix jacchus	52.95	1.00e-126	446.00
IUUC-Cfa-020393	Canis familiaris	54.67	5.00e-138	484.00
IUUC-Cpo-022166	Cavia porcellus	53.09	2.00e-125	442.00
IUUC-Csa-023654	Chlorocebus sabaeus	53.56	7.00e-134	470.00
IUUC-Cho-024403	Choloepus hoffmanni	52.81	8.00e-67	247.00
IUUC-Cin-025448	Ciona intestinalis	29.27	2.00e-15	75.50
IUUC-Dre-027754	Danio rerio	47.38	2.00e-113	402.00
IUUC-Dno-029630	Dasypus novemcinctus	53.56	2.00e-137	482.00
IUUC-Dor-031064	Dipodomys ordii	55.84	8.00e-100	357.00
IUUC-Ete-032901	Echinops telfairi	47.88	3.00e-128	451.00
IUUC-Eca-034234	Equus caballus	54.99	2.00e-151	528.00
IUUC-Eeu-035015	Erinaceus europaeus	49.47	3.00e-51	196.00
IUUC-Fca-036587	Felis catus	53.77	3.00e-138	484.00
IUUC-Gmo-038646	Gadus morhua	45.40	1.00e-97	349.00
IUUC-Gga-040124	Gallus gallus	76.90	1.00e-149	521.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.29	4.00e-105	375.00
IUUC-Ggo-045505	Gorilla gorilla	54.58	1.00e-135	476.00
IUUC-Hsa-046950	Homo sapiens	54.79	3.00e-136	478.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	53.96	1.00e-134	473.00
IUUC-Lch-050141	Latimeria chalumnae	48.79	2.00e-112	399.00
IUUC-Loc-051921	Lepisosteus oculatus	47.59	2.00e-110	392.00
IUUC-Laf-054281	Loxodonta africana	53.21	3.00e-135	474.00
IUUC-Mcc-055462	Macaca mulatta	50.81	4.00e-121	427.00
IUUC-Meu-056294	Macropus eugenii	54.99	4.00e-100	358.00
IUUC-Mga-059924	Meleagris gallopavo	72.48	0.00e+00	679.00
IUUC-Mmr-061428	Microcebus murinus	52.75	5.00e-143	500.00
IUUC-Mdo-062643	Monodelphis domestica	55.53	1.00e-147	515.00
IUUC-Mmu-063229	Mus musculus	52.65	9.00e-128	449.00
IUUC-Mpu-065782	Mustela putorius furo	54.16	1.00e-134	472.00
IUUC-Mlu-068105	Myotis lucifugus	50.20	1.00e-131	462.00
IUUC-Nle-069549	Nomascus leucogenys	54.79	2.00e-136	479.00
IUUC-Opr-070568	Ochotona princeps	52.46	4.00e-130	457.00
IUUC-Ont-072276	Oreochromis niloticus	45.69	1.00e-109	389.00
IUUC-Oan-072787	Ornithorhynchus anatinus	57.17	2.00e-142	498.00
IUUC-Ocu-074912	Oryctolagus cuniculus	50.92	3.00e-134	471.00
IUUC-Ola-087037	Oryzias latipes	44.53	1.00e-98	353.00
IUUC-Oga-088953	Otolemur garnettii	50.51	6.00e-126	444.00
IUUC-Oar-089202	Ovis aries	52.95	5.00e-145	507.00
IUUC-Ptr-090964	Pan troglodytes	54.79	1.00e-136	479.00
IUUC-Pan-091975	Papio anubis	54.58	7.00e-137	480.00
IUUC-Psi-093558	Pelodiscus sinensis	66.60	5.00e-166	577.00
IUUC-Pma-094500	Petromyzon marinus	53.45	4.00e-16	77.40
IUUC-Pfo-096454	Poecilia formosa	45.88	2.00e-110	392.00
IUUC-Pab-098123	Pongo abelii	54.58	5.00e-137	480.00
IUUC-Pca-101112	Procavia capensis	51.80	8.00e-126	443.00
IUUC-Pva-103098	Pteropus vampyrus	50.71	5.00e-130	457.00
IUUC-Rno-105930	Rattus norvegicus	53.97	2.00e-127	449.00
IUUC-Sha-107512	Sarcophilus harrisii	54.95	2.00e-134	472.00
IUUC-Sar-113584	Sorex araneus	50.00	3.00e-121	428.00
IUUC-Tgu-116766	Taeniopygia guttata	88.71	1.00e-150	525.00
IUUC-Tru-117829	Takifugu rubripes	46.36	2.00e-104	372.00
IUUC-Tsy-119268	Tarsius syrichta	50.77	4.00e-59	221.00
IUUC-Tni-120204	Tetraodon nigroviridis	46.54	6.00e-102	364.00
IUUC-Tbe-127840	Tupaia belangeri	53.95	3.00e-69	254.00
IUUC-Ttr-128863	Tursiops truncatus	52.34	2.00e-137	482.00
IUUC-Vpa-130718	Vicugna pacos	53.96	3.00e-135	474.00
IUUC-Xtr-132320	Xenopus tropicalis	45.35	1.00e-86	313.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence