iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036624

Ensembl Protein ID

ENSFALP00000005683.1

UniProt Accession

U3JSC9; U3JSC9_FICAL

Genbank Protein ID

ENSFALP00000005683

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGTO01011747

Gene Name

HCK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005462.1	ENSFALT00000005710.1	ENSFALP00000005683.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-16	59.9	63	118

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v +lydyea n ++L+++kG+ ++v+   e++++W+++ +  +g++G++P+n+v++++
   Q: 63   VVLALYDYEAMNAGDLSFQKGERMKVL---EKSGEWWQARSLVTGREGFIPSNYVAQVN 118
           6889***********************...**************************997 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGCVRSKEAG VQEKMIKTDP DPDPGPTILQ GHYVRDPTAT NKRSNHVHSM AVSLPEDGVG 60
DSVVLALYDY EAMNAGDLSF QKGERMKVLE KSGEWWQARS LVTGREGFIP SNYVAQVNSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTACCGG GAGGGGCGTG GCTGTACCGG GAGGGGCGTG GCTGTACCGG GAGGGGCGTG 60
GCTGTACCGG GAGGGGCGTG GCTGTACCGG GCATGCGGCG GGAGAGCAGC CGGGCAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

KEGG

fab:101812195

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	78.67	0.00e+00	810.00
IUUC-Apl-003285	Anas platyrhynchos	85.35	0.00e+00	902.00
IUUC-Aca-004724	Anolis carolinensis	77.54	0.00e+00	801.00
IUUC-Ame-011954	Astyanax mexicanus	74.46	0.00e+00	764.00
IUUC-Bta-013060	Bos taurus	77.76	0.00e+00	804.00
IUUC-Cja-019817	Callithrix jacchus	77.50	0.00e+00	798.00
IUUC-Cfa-020511	Canis familiaris	77.95	0.00e+00	808.00
IUUC-Cpo-022538	Cavia porcellus	76.82	0.00e+00	792.00
IUUC-Csa-024143	Chlorocebus sabaeus	77.84	0.00e+00	802.00
IUUC-Dre-028157	Danio rerio	74.07	0.00e+00	784.00
IUUC-Dno-029761	Dasypus novemcinctus	76.38	0.00e+00	794.00
IUUC-Dor-030892	Dipodomys ordii	65.09	0.00e+00	675.00
IUUC-Eca-034090	Equus caballus	76.18	0.00e+00	782.00
IUUC-Fca-035937	Felis catus	77.60	0.00e+00	784.00
IUUC-Gmo-039009	Gadus morhua	70.87	0.00e+00	756.00
IUUC-Gga-040296	Gallus gallus	80.67	0.00e+00	860.00
IUUC-Gac-042362	Gasterosteus aculeatus	74.26	0.00e+00	786.00
IUUC-Ggo-044570	Gorilla gorilla	77.65	0.00e+00	800.00
IUUC-Hsa-046378	Homo sapiens	78.24	0.00e+00	806.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	77.01	0.00e+00	797.00
IUUC-Loc-052904	Lepisosteus oculatus	76.56	0.00e+00	816.00
IUUC-Laf-053654	Loxodonta africana	79.17	0.00e+00	815.00
IUUC-Mcc-055317	Macaca mulatta	77.84	0.00e+00	806.00
IUUC-Mga-060194	Meleagris gallopavo	85.56	0.00e+00	816.00
IUUC-Mmr-061510	Microcebus murinus	76.91	0.00e+00	797.00
IUUC-Mdo-062035	Monodelphis domestica	77.21	0.00e+00	808.00
IUUC-Mmu-064037	Mus musculus	77.65	0.00e+00	809.00
IUUC-Mpu-066874	Mustela putorius furo	78.19	0.00e+00	813.00
IUUC-Mlu-068202	Myotis lucifugus	75.59	0.00e+00	779.00
IUUC-Nle-069222	Nomascus leucogenys	78.00	0.00e+00	806.00
IUUC-Opr-070705	Ochotona princeps	76.23	0.00e+00	792.00
IUUC-Ont-072347	Oreochromis niloticus	80.58	0.00e+00	753.00
IUUC-Ocu-074490	Oryctolagus cuniculus	76.82	0.00e+00	796.00
IUUC-Ola-086521	Oryzias latipes	79.38	0.00e+00	769.00
IUUC-Oga-088153	Otolemur garnettii	76.82	0.00e+00	792.00
IUUC-Oar-090184	Ovis aries	76.91	0.00e+00	796.00
IUUC-Ptr-090505	Pan troglodytes	74.12	0.00e+00	749.00
IUUC-Pan-092260	Papio anubis	78.04	0.00e+00	807.00
IUUC-Pma-094311	Petromyzon marinus	69.41	0.00e+00	694.00
IUUC-Pfo-096566	Poecilia formosa	73.97	0.00e+00	795.00
IUUC-Pva-103021	Pteropus vampyrus	78.00	0.00e+00	808.00
IUUC-Rno-105309	Rattus norvegicus	77.65	0.00e+00	810.00
IUUC-Sha-107099	Sarcophilus harrisii	76.17	0.00e+00	801.00
IUUC-Sit-110451	Setaria italica	31.16	5.00e-24	106.00
IUUC-Tgu-116912	Taeniopygia guttata	93.89	0.00e+00	989.00
IUUC-Tru-118449	Takifugu rubripes	79.82	0.00e+00	752.00
IUUC-Tae-123837	Triticum aestivum	27.74	7.00e-22	99.00
IUUC-Tbe-128144	Tupaia belangeri	75.39	0.00e+00	689.00
IUUC-Vvi-131372	Vitis vinifera	30.28	8.00e-22	99.00
IUUC-Xtr-132224	Xenopus tropicalis	68.61	0.00e+00	678.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence