iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-116639

Ensembl Protein ID

ENSTGUP00000005580.1

UniProt Accession

H0Z4T5; H0Z4T5_TAEGU

Genbank Protein ID

ENSTGUP00000005580

Protein Name

Histone acetyltransferase

Genbank Nucleotide ID

ABQF01056199

Gene Name

KAT6A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000005382.1	ENSTGUT00000005637.1	ENSTGUP00000005580.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-09	38.0	264	313

Active Site

Position(s)	Description	Evidence
679	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 264  KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 313
           68999******99*********************.9*****97.******85 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK LDGKPNVDWN KLIKRAIEGL AESGGSSLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAAAAC TCGCCAACCC GCTGTATACA GAGTGGATTT TGGAGGCAAT CAAAAAGGTA 60
AAGAAGCAAA AACAGCGACC TTCAGAGGAG AGGATATGCA ACGCTGTGTC ATCTTCACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00526--H15
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0000786--C:nucleosome
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	83.28	0.00e+00	2754.00
IUUC-Aca-004549	Anolis carolinensis	75.50	0.00e+00	1991.00
IUUC-Ame-010711	Astyanax mexicanus	63.18	4.00e-177	616.00
IUUC-Bta-013426	Bos taurus	81.30	0.00e+00	1769.00
IUUC-Cja-019124	Callithrix jacchus	82.39	0.00e+00	1801.00
IUUC-Cfa-021165	Canis familiaris	82.19	0.00e+00	2182.00
IUUC-Cpo-022332	Cavia porcellus	75.56	0.00e+00	1422.00
IUUC-Cne-026801	Cryptococcus neoformans	63.59	1.00e-73	271.00
IUUC-Dre-028624	Danio rerio	72.79	0.00e+00	1204.00
IUUC-Dno-029878	Dasypus novemcinctus	76.74	0.00e+00	1676.00
IUUC-Ete-032342	Echinops telfairi	85.00	0.00e+00	1680.00
IUUC-Eca-033925	Equus caballus	81.70	0.00e+00	2159.00
IUUC-Fca-035985	Felis catus	82.31	0.00e+00	2195.00
IUUC-Gmo-039182	Gadus morhua	74.31	0.00e+00	1196.00
IUUC-Gga-041028	Gallus gallus	91.82	0.00e+00	2047.00
IUUC-Gac-042131	Gasterosteus aculeatus	70.81	0.00e+00	1191.00
IUUC-Ggo-044664	Gorilla gorilla	81.33	0.00e+00	1790.00
IUUC-Hsa-046832	Homo sapiens	81.41	0.00e+00	1796.00
IUUC-Loc-052537	Lepisosteus oculatus	77.03	0.00e+00	1255.00
IUUC-Laf-053686	Loxodonta africana	82.74	0.00e+00	2170.00
IUUC-Mcc-055429	Macaca mulatta	81.75	0.00e+00	1807.00
IUUC-Mvi-060531	Microbotryum violaceum	54.91	3.00e-72	266.00
IUUC-Mmr-061249	Microcebus murinus	79.97	0.00e+00	1772.00
IUUC-Mdo-062826	Monodelphis domestica	81.35	0.00e+00	953.00
IUUC-Mmu-063474	Mus musculus	79.62	0.00e+00	1796.00
IUUC-Mpu-066585	Mustela putorius furo	81.91	0.00e+00	2185.00
IUUC-Mlu-066965	Myotis lucifugus	81.20	0.00e+00	2112.00
IUUC-Nle-069270	Nomascus leucogenys	81.33	0.00e+00	1793.00
IUUC-Opr-070963	Ochotona princeps	70.87	0.00e+00	1486.00
IUUC-Ont-071466	Oreochromis niloticus	71.89	0.00e+00	631.00
IUUC-Oan-073367	Ornithorhynchus anatinus	85.10	0.00e+00	2252.00
IUUC-Ocu-074100	Oryctolagus cuniculus	75.99	0.00e+00	1618.00
IUUC-Ola-087293	Oryzias latipes	74.09	0.00e+00	1190.00
IUUC-Oga-089052	Otolemur garnettii	87.35	0.00e+00	854.00
IUUC-Oar-089692	Ovis aries	80.02	0.00e+00	1700.00
IUUC-Ptr-091107	Pan troglodytes	81.41	0.00e+00	1779.00
IUUC-Pan-092524	Papio anubis	81.52	0.00e+00	1803.00
IUUC-Pfo-096641	Poecilia formosa	71.34	0.00e+00	1187.00
IUUC-Pab-098311	Pongo abelii	81.27	0.00e+00	1809.00
IUUC-Pca-100810	Procavia capensis	77.31	0.00e+00	1556.00
IUUC-Pgr-103522	Puccinia graminis	50.00	1.00e-68	254.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	37.04	1.00e-46	181.00
IUUC-Rno-104990	Rattus norvegicus	79.95	0.00e+00	1744.00
IUUC-Sha-106816	Sarcophilus harrisii	84.05	0.00e+00	2206.00
IUUC-Sre-115066	Sporisorium reilianum	55.56	1.00e-77	285.00
IUUC-Tru-118571	Takifugu rubripes	73.15	0.00e+00	1208.00
IUUC-Tni-119936	Tetraodon nigroviridis	74.72	0.00e+00	1230.00
IUUC-Tbe-127928	Tupaia belangeri	94.79	0.00e+00	1549.00
IUUC-Uma-129445	Ustilago maydis	56.84	2.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence