iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020782

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03017742

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000012305.3	ENSCAFT00000019537.3	ENSCAFP00000018122.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.70e-18	65.4	78	144
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.70e-10	39.4	176	206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e +e+k k++v+++ v+p v+  ++k+lY+ ++d+n+
   Q: 78   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEGK-KKEVVLDNVDPAVLDLIIKYLYSASIDLND 144
           9************************************.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 176  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 206
           56***************************99 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEEKPQPLEA LTVEQIQDDV EIDSDDHTDA FVAYFADGNK VTHKMDSQRE LTEELRLYQS 60
TLLQDGLKDL LDEKKFIDCT LKAGDKSLPC HRLILSACSP YFREYFLSEI DEGKKKEVVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAATAAT AAGGTGATGG AAGGAAGGCG TTTTAATTCG TTCGAAAAGT TTCTGAGTGC 60
CAGCTCCTGT GGAAAGCGAG CTGGAGTATC GGGCCCTGTC CTGGGGGTGC TCAGGTACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	98.85	0.00e+00	1200.00
IUUC-Apl-003866	Anas platyrhynchos	86.18	0.00e+00	1045.00
IUUC-Ame-011172	Astyanax mexicanus	62.35	0.00e+00	759.00
IUUC-Bta-012925	Bos taurus	98.51	0.00e+00	1195.00
IUUC-Bci-013875	Botrytis cinerea	29.11	2.00e-18	86.30
IUUC-Cja-019348	Callithrix jacchus	97.69	0.00e+00	1190.00
IUUC-Cpo-021825	Cavia porcellus	94.22	0.00e+00	1144.00
IUUC-Csa-023184	Chlorocebus sabaeus	97.50	0.00e+00	1016.00
IUUC-Cin-025237	Ciona intestinalis	29.16	3.00e-69	256.00
IUUC-Dre-028278	Danio rerio	60.56	0.00e+00	777.00
IUUC-Dno-029516	Dasypus novemcinctus	96.20	0.00e+00	1175.00
IUUC-Dor-030850	Dipodomys ordii	94.22	0.00e+00	765.00
IUUC-Ete-032697	Echinops telfairi	94.39	0.00e+00	1130.00
IUUC-Eca-033714	Equus caballus	98.52	0.00e+00	1199.00
IUUC-Eeu-035245	Erinaceus europaeus	95.25	0.00e+00	1075.00
IUUC-Fal-037632	Ficedula albicollis	56.46	0.00e+00	684.00
IUUC-Gmo-039392	Gadus morhua	58.13	0.00e+00	736.00
IUUC-Ggr-040041	Gaeumannomyces graminis	28.28	5.00e-08	52.00
IUUC-Gga-041106	Gallus gallus	85.64	0.00e+00	1055.00
IUUC-Gac-042252	Gasterosteus aculeatus	61.49	0.00e+00	781.00
IUUC-Ggo-044817	Gorilla gorilla	97.69	0.00e+00	1189.00
IUUC-Hsa-046620	Homo sapiens	97.85	0.00e+00	1188.00
IUUC-Lch-050477	Latimeria chalumnae	70.13	0.00e+00	860.00
IUUC-Loc-051955	Lepisosteus oculatus	71.00	0.00e+00	917.00
IUUC-Laf-053500	Loxodonta africana	97.19	0.00e+00	1179.00
IUUC-Mcc-055316	Macaca mulatta	97.69	0.00e+00	1189.00
IUUC-Mga-059451	Meleagris gallopavo	57.19	0.00e+00	711.00
IUUC-Mmr-061444	Microcebus murinus	98.35	0.00e+00	1193.00
IUUC-Mmu-064147	Mus musculus	96.20	0.00e+00	1173.00
IUUC-Mlu-067481	Myotis lucifugus	95.05	0.00e+00	1165.00
IUUC-Nle-069339	Nomascus leucogenys	98.02	0.00e+00	1191.00
IUUC-Opr-070703	Ochotona princeps	97.03	0.00e+00	1135.00
IUUC-Ont-072420	Oreochromis niloticus	60.60	0.00e+00	800.00
IUUC-Oan-073476	Ornithorhynchus anatinus	93.73	0.00e+00	1147.00
IUUC-Ocu-074248	Oryctolagus cuniculus	97.38	0.00e+00	1275.00
IUUC-Ola-086361	Oryzias latipes	62.13	0.00e+00	788.00
IUUC-Oar-090349	Ovis aries	98.02	0.00e+00	1190.00
IUUC-Pan-092069	Papio anubis	97.85	0.00e+00	1190.00
IUUC-Psi-093671	Pelodiscus sinensis	88.45	0.00e+00	1054.00
IUUC-Pma-094586	Petromyzon marinus	57.14	5.00e-94	337.00
IUUC-Pfo-096122	Poecilia formosa	62.75	0.00e+00	816.00
IUUC-Pab-098711	Pongo abelii	97.69	0.00e+00	1188.00
IUUC-Pca-100495	Procavia capensis	88.61	0.00e+00	1057.00
IUUC-Pva-102401	Pteropus vampyrus	97.69	0.00e+00	1189.00
IUUC-Rno-105969	Rattus norvegicus	95.87	0.00e+00	1170.00
IUUC-Sha-107091	Sarcophilus harrisii	52.63	0.00e+00	682.00
IUUC-Sar-113405	Sorex araneus	93.73	0.00e+00	1130.00
IUUC-Tgu-116725	Taeniopygia guttata	85.81	0.00e+00	1074.00
IUUC-Tru-117743	Takifugu rubripes	59.38	0.00e+00	767.00
IUUC-Tsy-119225	Tarsius syrichta	90.59	0.00e+00	1085.00
IUUC-Tni-120547	Tetraodon nigroviridis	62.58	0.00e+00	798.00
IUUC-Ttr-128645	Tursiops truncatus	98.18	0.00e+00	1193.00
IUUC-Vpa-130714	Vicugna pacos	98.84	0.00e+00	1201.00
IUUC-Xtr-132144	Xenopus tropicalis	75.93	0.00e+00	949.00
IUUC-Xma-133860	Xiphophorus maculatus	62.91	0.00e+00	817.00
IUUC-Yli-134535	Yarrowia lipolytica	23.03	3.00e-06	45.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence