iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132289

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01115775

Gene Name

klhl8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000006419.3	ENSXETT00000014050.2	ENSXETP00000014050.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-16	61.0	63	127
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.00e-10	39.8	162	193

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+++ e+k +  +ei+d + ++ ++l+kF+Y++ ++
   Q: 63   CDVTLKVGSKLIPCHKLVLACVIPYFRAMFLSDMAETK-QTLIEIQDFDGDAIEDLVKFSYSSCVT 127
           9************************************9.**********************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a++++++hF+
   Q: 162  PSNCLAVRAFAESHNRVDLMDMADRYACDHFT 193
           89*****************************7 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MASESVLPEQ VKPRQAKGRR QIQREKSLTS EVDGDGTFVF EADEAWKEFH RSLLHFYEVG 60
ELCDVTLKVG SKLIPCHKLV LACVIPYFRA MFLSDMAETK QTLIEIQDFD GDAIEDLVKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCATCAG AATCTGTGCT CCCTGAGCAG GTCAAGCCAA GACAAGCTAA AGGACGAAGA 60
CAGATCCAGC GGGAGAAATC CTTAACCAGT GAGGTGGATG GTGATGGCAC TTTTGTCTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	84.34	0.00e+00	1038.00
IUUC-Apl-003978	Anas platyrhynchos	84.11	0.00e+00	1026.00
IUUC-Aca-004958	Anolis carolinensis	80.83	0.00e+00	986.00
IUUC-Ame-011139	Astyanax mexicanus	79.58	0.00e+00	977.00
IUUC-Bta-013142	Bos taurus	84.11	0.00e+00	1032.00
IUUC-Cel-018551	Caenorhabditis elegans	39.00	3.00e-118	419.00
IUUC-Cja-019650	Callithrix jacchus	83.85	0.00e+00	1036.00
IUUC-Cfa-021046	Canis familiaris	84.66	0.00e+00	1038.00
IUUC-Cpo-022445	Cavia porcellus	82.96	0.00e+00	994.00
IUUC-Csa-023642	Chlorocebus sabaeus	83.68	0.00e+00	1035.00
IUUC-Cho-025012	Choloepus hoffmanni	72.70	2.00e-153	535.00
IUUC-Dre-027723	Danio rerio	78.97	0.00e+00	969.00
IUUC-Dno-028964	Dasypus novemcinctus	83.79	0.00e+00	904.00
IUUC-Ete-032815	Echinops telfairi	81.24	0.00e+00	996.00
IUUC-Eca-034162	Equus caballus	83.48	0.00e+00	1016.00
IUUC-Eeu-034660	Erinaceus europaeus	83.62	0.00e+00	1030.00
IUUC-Fca-035659	Felis catus	83.82	0.00e+00	1034.00
IUUC-Fal-037619	Ficedula albicollis	84.11	0.00e+00	1038.00
IUUC-Gmo-038546	Gadus morhua	82.10	0.00e+00	975.00
IUUC-Gga-040770	Gallus gallus	84.11	0.00e+00	1031.00
IUUC-Gac-042557	Gasterosteus aculeatus	78.55	0.00e+00	979.00
IUUC-Ggo-044741	Gorilla gorilla	83.68	0.00e+00	1034.00
IUUC-Hsa-046025	Homo sapiens	83.68	0.00e+00	1035.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	87.08	0.00e+00	955.00
IUUC-Loc-052834	Lepisosteus oculatus	80.62	0.00e+00	947.00
IUUC-Laf-054513	Loxodonta africana	83.30	0.00e+00	1017.00
IUUC-Mcc-054707	Macaca mulatta	83.51	0.00e+00	1030.00
IUUC-Meu-056779	Macropus eugenii	82.19	0.00e+00	1012.00
IUUC-Mtr-058180	Medicago truncatula	32.70	8.00e-36	145.00
IUUC-Mga-059676	Meleagris gallopavo	83.77	0.00e+00	1027.00
IUUC-Mmr-061359	Microcebus murinus	82.65	0.00e+00	1013.00
IUUC-Mdo-062527	Monodelphis domestica	81.88	0.00e+00	1012.00
IUUC-Mmu-063112	Mus musculus	81.73	0.00e+00	1015.00
IUUC-Mpu-065800	Mustela putorius furo	83.99	0.00e+00	1034.00
IUUC-Mlu-067536	Myotis lucifugus	82.96	0.00e+00	1003.00
IUUC-Nle-069397	Nomascus leucogenys	83.68	0.00e+00	1033.00
IUUC-Opr-070599	Ochotona princeps	83.24	0.00e+00	895.00
IUUC-Ont-072580	Oreochromis niloticus	79.41	0.00e+00	986.00
IUUC-Oan-073180	Ornithorhynchus anatinus	83.30	0.00e+00	1019.00
IUUC-Ocu-074026	Oryctolagus cuniculus	82.79	0.00e+00	1012.00
IUUC-Ola-086776	Oryzias latipes	80.81	0.00e+00	951.00
IUUC-Oga-088651	Otolemur garnettii	83.53	0.00e+00	1028.00
IUUC-Oar-089567	Ovis aries	82.56	0.00e+00	1005.00
IUUC-Ptr-091564	Pan troglodytes	83.68	0.00e+00	1034.00
IUUC-Pan-092578	Papio anubis	83.68	0.00e+00	1035.00
IUUC-Psi-093635	Pelodiscus sinensis	84.11	0.00e+00	1015.00
IUUC-Pma-094660	Petromyzon marinus	59.64	0.00e+00	690.00
IUUC-Pfo-097507	Poecilia formosa	79.93	0.00e+00	993.00
IUUC-Pab-098025	Pongo abelii	83.68	0.00e+00	1034.00
IUUC-Pca-101046	Procavia capensis	77.06	2.00e-150	525.00
IUUC-Pva-102359	Pteropus vampyrus	87.33	0.00e+00	828.00
IUUC-Rno-105750	Rattus norvegicus	81.99	0.00e+00	997.00
IUUC-Sha-107513	Sarcophilus harrisii	83.51	0.00e+00	1025.00
IUUC-Stu-112032	Solanum tuberosum	35.68	4.00e-39	155.00
IUUC-Sar-113616	Sorex araneus	63.36	4.00e-107	381.00
IUUC-Ssc-116205	Sus scrofa	84.24	0.00e+00	910.00
IUUC-Tgu-117435	Taeniopygia guttata	84.46	0.00e+00	1038.00
IUUC-Tru-118709	Takifugu rubripes	78.55	0.00e+00	978.00
IUUC-Tsy-119466	Tarsius syrichta	87.65	0.00e+00	958.00
IUUC-Tni-119988	Tetraodon nigroviridis	78.76	0.00e+00	975.00
IUUC-Tbe-127704	Tupaia belangeri	85.49	0.00e+00	914.00
IUUC-Ttr-128892	Tursiops truncatus	86.12	0.00e+00	785.00
IUUC-Vpa-130545	Vicugna pacos	83.43	0.00e+00	909.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence