KW-0002--3D-structure
KW-0024--Alternative initiation
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0985--Congenital erythrocytosis
KW-0963--Cytoplasm
KW-0225--Disease mutation
KW-0472--Membrane
KW-0539--Nucleus
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0043--Tumor suppressor
KW-0833--Ubl conjugation pathway

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

PF01847--VHL
PF17211--VHL_C

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0016020--C:membrane
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0030891--C:VCB complex
GO:0019899--F:enzyme binding
GO:0008134--F:transcription factor binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0000902--P:cell morphogenesis
GO:0043066--P:negative regulation of apoptotic process
GO:0008285--P:negative regulation of cell proliferation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0061428--P:negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0045597--P:positive regulation of cell differentiation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0050821--P:protein stabilization
GO:0016567--P:protein ubiquitination
GO:0006508--P:proteolysis
GO:0061418--P:regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0006355--P:regulation of transcription, DNA-templated