iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026098

UUCD1 version

UUC-CiS-00376

Ensembl Protein ID

ENSCSAVP00000008099.1

UniProt Accession

H2YRY9; H2YRY9_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000004819.1	ENSCSAVT00000008206.1	ENSCSAVP00000008098.1
ENSCSAVG00000004819.1	ENSCSAVT00000008207.1	ENSCSAVP00000008099.1
ENSCSAVG00000004819.1	ENSCSAVT00000008208.1	ENSCSAVP00000008100.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.40e-96	323.0	347	533

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 116  elykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevipl 203
           e+y+slk+i+en   d ++l  dl f+v+ee++g++k++eLkpgGe+i+V+n+Nk+eY++lv+++r+ ++++eq+++f +Gfne+ip 
   Q: 347  EYYNSLKWILEN---DPTDL--DLCFTVDEELFGQMKVNELKPGGEDIKVNNDNKREYIQLVIKWRFVSRVQEQMKSFLQGFNELIPS 429
           89********99...78886..5556678*********************************************************** PP
   S: 204  ellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlf 287
           +l+++F+e+elell+cG  ++dv+d++++t+ykg+y++++ +iqwFw+++  ++ e r +fLqFvTg+sr+P++Gf el     p+lf
   Q: 430  NLVKIFDENELELLMCGLGDVDVNDWRRNTNYKGDYSANHIVIQWFWRAVLLMDPELRVRFLQFVTGTSRVPMNGFGELWgsngPQLF 517
           **************************************************************************************** PP
   S: 288  virkdasddrlPssnT 303
           +++k+++ ++lP+++T
   Q: 518  TVEKWGTAEKLPRAHT 533
           ***************9 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

LPDGWEARTD AKSGRKYYVD HINKRTSWHR PRAIPVNRAR NERCYTGLEM NAVYVLWELY 60
RARNKRWLWL EMNAGYVLWE LYRARNEGWL CVVGQRASST SDRSSSPSNI SSSPSAQKYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCACTGAGG CAGATGGGAG GTTACCCGAT GGATGGGAGG CCAGGACCGA TGCGAAGTCC 60
GGTCGGAAGT ATTACGTCGA TCATATCAAC AAACGAACCT CTTGGCACCG ACCCAGAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00632--HECT
PF00397--WW

SMART

SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001201	Ailuropoda melanoleuca	68.90	0.00e+00	650.00
IUUC-Apl-003893	Anas platyrhynchos	57.88	0.00e+00	633.00
IUUC-Aca-004744	Anolis carolinensis	55.69	7.00e-170	589.00
IUUC-Ame-011138	Astyanax mexicanus	68.62	5.00e-178	616.00
IUUC-Bta-012679	Bos taurus	57.80	0.00e+00	633.00
IUUC-Cel-018564	Caenorhabditis elegans	51.69	6.00e-134	469.00
IUUC-Cja-018732	Callithrix jacchus	58.13	0.00e+00	630.00
IUUC-Cfa-020258	Canis familiaris	68.90	0.00e+00	649.00
IUUC-Cpo-021671	Cavia porcellus	57.80	0.00e+00	633.00
IUUC-Csa-023344	Chlorocebus sabaeus	56.01	8.00e-180	622.00
IUUC-Cho-024832	Choloepus hoffmanni	69.03	2.00e-145	508.00
IUUC-Cin-025157	Ciona intestinalis	76.38	0.00e+00	857.00
IUUC-Dre-027770	Danio rerio	66.37	2.00e-178	618.00
IUUC-Dno-029466	Dasypus novemcinctus	57.80	0.00e+00	633.00
IUUC-Dor-030138	Dipodomys ordii	56.61	4.00e-176	610.00
IUUC-Dme-032166	Drosophila melanogaster	63.21	2.00e-172	598.00
IUUC-Ete-033145	Echinops telfairi	53.72	1.00e-164	571.00
IUUC-Eca-033445	Equus caballus	57.80	0.00e+00	632.00
IUUC-Eeu-035247	Erinaceus europaeus	66.22	1.00e-177	615.00
IUUC-Fca-036384	Felis catus	68.60	0.00e+00	643.00
IUUC-Fal-037604	Ficedula albicollis	55.99	2.00e-179	621.00
IUUC-Gmo-039674	Gadus morhua	67.79	2.00e-173	601.00
IUUC-Gga-040703	Gallus gallus	57.88	0.00e+00	633.00
IUUC-Gac-042020	Gasterosteus aculeatus	67.57	5.00e-174	603.00
IUUC-Ggo-045332	Gorilla gorilla	57.80	0.00e+00	631.00
IUUC-Hsa-045968	Homo sapiens	57.80	0.00e+00	632.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	66.44	5.00e-172	596.00
IUUC-Lch-050445	Latimeria chalumnae	57.12	0.00e+00	637.00
IUUC-Loc-052645	Lepisosteus oculatus	68.02	3.00e-178	617.00
IUUC-Laf-053850	Loxodonta africana	57.80	0.00e+00	632.00
IUUC-Mcc-055821	Macaca mulatta	57.98	0.00e+00	634.00
IUUC-Meu-056897	Macropus eugenii	67.59	9.00e-101	360.00
IUUC-Mga-059362	Meleagris gallopavo	61.09	0.00e+00	653.00
IUUC-Mmr-061061	Microcebus murinus	68.68	0.00e+00	646.00
IUUC-Mdo-062178	Monodelphis domestica	56.27	0.00e+00	648.00
IUUC-Mmu-064136	Mus musculus	57.70	0.00e+00	634.00
IUUC-Mpu-066765	Mustela putorius furo	57.98	0.00e+00	633.00
IUUC-Mlu-067565	Myotis lucifugus	58.87	0.00e+00	631.00
IUUC-Nle-069225	Nomascus leucogenys	68.76	0.00e+00	646.00
IUUC-Opr-071044	Ochotona princeps	57.35	0.00e+00	625.00
IUUC-Ont-071664	Oreochromis niloticus	58.01	1.00e-173	602.00
IUUC-Oan-073019	Ornithorhynchus anatinus	67.71	2.00e-177	614.00
IUUC-Ocu-074160	Oryctolagus cuniculus	66.22	9.00e-178	615.00
IUUC-Ola-087467	Oryzias latipes	67.26	1.00e-174	605.00
IUUC-Oga-088460	Otolemur garnettii	57.80	0.00e+00	631.00
IUUC-Oar-090198	Ovis aries	57.80	0.00e+00	632.00
IUUC-Ptr-090939	Pan troglodytes	57.80	0.00e+00	632.00
IUUC-Pan-092284	Papio anubis	57.80	0.00e+00	632.00
IUUC-Psi-093645	Pelodiscus sinensis	57.47	0.00e+00	632.00
IUUC-Pma-094364	Petromyzon marinus	66.59	2.00e-174	603.00
IUUC-Pfo-096768	Poecilia formosa	67.34	8.00e-176	608.00
IUUC-Pab-098088	Pongo abelii	57.80	0.00e+00	632.00
IUUC-Pca-100568	Procavia capensis	61.35	3.00e-162	564.00
IUUC-Pva-102354	Pteropus vampyrus	58.87	0.00e+00	631.00
IUUC-Rno-105318	Rattus norvegicus	57.70	0.00e+00	634.00
IUUC-Sha-107482	Sarcophilus harrisii	65.85	4.00e-176	610.00
IUUC-Ssc-115950	Sus scrofa	63.66	2.00e-165	574.00
IUUC-Tgu-117130	Taeniopygia guttata	57.60	0.00e+00	629.00
IUUC-Tru-117675	Takifugu rubripes	68.69	8.00e-180	622.00
IUUC-Tsy-119492	Tarsius syrichta	57.27	0.00e+00	627.00
IUUC-Tni-119993	Tetraodon nigroviridis	68.24	5.00e-175	606.00
IUUC-Tbe-127408	Tupaia belangeri	63.53	8.00e-167	579.00
IUUC-Ttr-128235	Tursiops truncatus	66.00	3.00e-177	613.00
IUUC-Vpa-130503	Vicugna pacos	68.01	2.00e-175	608.00
IUUC-Xtr-132859	Xenopus tropicalis	57.85	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence