iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088964

Ensembl Protein ID

ENSOGAP00000021994.1

UniProt Accession

H0Y0V1; H0Y0V1_OTOGA

Genbank Protein ID

ENSOGAP00000021994

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03061676

Gene Name

POC1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000032245.1	ENSOGAT00000026296.1	ENSOGAP00000021994.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-59	194.2	143	178
UBD/Beta-Prp	5.40e-105	350.8	15	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v+c +f +d +l+vs+sdD+t+k+WD  +  +
   Q: 143  HINWVRCAKFsPDgRLIVSASDDKTVKLWDKNSREC 178
           999********999****************776666 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           kg h + +tcv+fs +k++la+gs+d+++ vw +++++   ++ gh+++vt+v+fsp+g +l++gs+D+t+++w ++      ++++h+
   Q: 15   KG-HRDAVTCVDFSLNKKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHT 102
           44.5557788****************************************************************7775555667899** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsv 183
           ++v+s++f+ +g++lv++s+d+ti+vw ++ ++ l   ls+h  +v+c++++pdg+l+vs+s+D+tv+lWd ++ ++++   + h + v
   Q: 103  ATVRSVHFCSDGQSLVTASDDKTIKVWSTHRQKFLF-SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKNSRECIYSYCE-HGGFV 189
           ***************************999999999.********************************************98.***** PP
   S: 184  yslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
           + ++f+++g++++++++d+tvk+wd++t + ++ +
   Q: 190  TYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY 224
           ***************************99988876 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MALPQEDPSL ERHFKGHRDA VTCVDFSLNK KQLASGSMDS CLMVWHMKPQ SRAYRFTGHK 60
DAVTCVNFSP SGHLLASGSR DKTVRIWVPN VKGESTVFRA HTATVRSVHF CSDGQSLVTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCTCC CCCAGGAGGA TCCCTCGCTG GAGAGGCATT TTAAGGGCCA CCGAGATGCA 60
GTTACCTGTG TGGACTTCAG TCTCAACAAG AAACAGCTGG GTAAGAGGAG ATGTCCTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000922--C:spindle pole
GO:0003431--P:growth plate cartilage chondrocyte development
GO:0007052--P:mitotic spindle organization
GO:1905515--P:non-motile cilium assembly
GO:0010825--P:positive regulation of centrosome duplication
GO:0007283--P:spermatogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001513	Ailuropoda melanoleuca	86.55	0.00e+00	708.00
IUUC-Apl-003466	Anas platyrhynchos	73.87	6.00e-174	603.00
IUUC-Aca-004323	Anolis carolinensis	66.74	1.00e-166	579.00
IUUC-Bta-012484	Bos taurus	86.14	0.00e+00	722.00
IUUC-Cja-019067	Callithrix jacchus	85.33	0.00e+00	733.00
IUUC-Cfa-020439	Canis familiaris	85.37	0.00e+00	719.00
IUUC-Cpo-021403	Cavia porcellus	83.86	0.00e+00	719.00
IUUC-Cre-022724	Chlamydomonas reinhardtii	51.72	1.00e-109	389.00
IUUC-Csa-023479	Chlorocebus sabaeus	86.56	0.00e+00	638.00
IUUC-Cho-024354	Choloepus hoffmanni	87.27	7.00e-114	402.00
IUUC-Cin-025258	Ciona intestinalis	74.17	1.00e-143	503.00
IUUC-Csv-025955	Ciona savignyi	65.62	2.00e-135	475.00
IUUC-Dno-029467	Dasypus novemcinctus	79.09	1.00e-127	448.00
IUUC-Dor-030399	Dipodomys ordii	84.15	0.00e+00	711.00
IUUC-Dme-032182	Drosophila melanogaster	46.28	4.00e-80	291.00
IUUC-Eca-034425	Equus caballus	86.55	0.00e+00	704.00
IUUC-Eeu-034607	Erinaceus europaeus	73.90	2.00e-167	581.00
IUUC-Fca-035627	Felis catus	86.88	0.00e+00	707.00
IUUC-Fal-037381	Ficedula albicollis	71.68	3.00e-172	597.00
IUUC-Gmo-038489	Gadus morhua	64.38	9.00e-150	523.00
IUUC-Gga-040559	Gallus gallus	70.90	1.00e-167	582.00
IUUC-Gac-041453	Gasterosteus aculeatus	66.08	8.00e-159	553.00
IUUC-Ggo-044773	Gorilla gorilla	86.59	0.00e+00	701.00
IUUC-Hsa-045823	Homo sapiens	87.07	0.00e+00	705.00
IUUC-Itr-048560	Ictidomys tridecemlineatus	87.16	0.00e+00	743.00
IUUC-Lch-050558	Latimeria chalumnae	65.57	3.00e-162	564.00
IUUC-Loc-052836	Lepisosteus oculatus	64.38	2.00e-164	572.00
IUUC-Laf-053974	Loxodonta africana	78.00	1.00e-179	621.00
IUUC-Mcc-055494	Macaca mulatta	85.02	0.00e+00	694.00
IUUC-Meu-056646	Macropus eugenii	75.51	1.00e-129	456.00
IUUC-Mga-059295	Meleagris gallopavo	65.32	3.00e-161	561.00
IUUC-Mmr-061040	Microcebus murinus	89.24	0.00e+00	756.00
IUUC-Mdo-062519	Monodelphis domestica	78.65	9.00e-178	615.00
IUUC-Mmu-063759	Mus musculus	94.67	3.00e-172	597.00
IUUC-Mpu-066442	Mustela putorius furo	86.10	0.00e+00	703.00
IUUC-Mlu-068163	Myotis lucifugus	84.56	0.00e+00	709.00
IUUC-Nle-070160	Nomascus leucogenys	86.10	0.00e+00	701.00
IUUC-Opr-070192	Ochotona princeps	82.67	9.00e-177	612.00
IUUC-Ont-072539	Oreochromis niloticus	70.93	4.00e-150	524.00
IUUC-Oan-072834	Ornithorhynchus anatinus	61.92	8.00e-113	399.00
IUUC-Ocu-074624	Oryctolagus cuniculus	84.68	0.00e+00	658.00
IUUC-Ola-087268	Oryzias latipes	59.58	4.00e-147	514.00
IUUC-Oar-090202	Ovis aries	86.06	0.00e+00	695.00
IUUC-Ptr-091164	Pan troglodytes	86.80	0.00e+00	706.00
IUUC-Pan-092805	Papio anubis	86.02	0.00e+00	635.00
IUUC-Psi-093359	Pelodiscus sinensis	84.11	3.00e-165	574.00
IUUC-Pma-094425	Petromyzon marinus	77.85	7.00e-152	530.00
IUUC-Pfo-096741	Poecilia formosa	74.32	8.00e-141	493.00
IUUC-Pab-098376	Pongo abelii	87.32	0.00e+00	743.00
IUUC-Pca-101122	Procavia capensis	83.66	0.00e+00	697.00
IUUC-Pva-103104	Pteropus vampyrus	80.67	7.00e-152	530.00
IUUC-Rno-105282	Rattus norvegicus	82.84	0.00e+00	640.00
IUUC-Sha-106840	Sarcophilus harrisii	80.42	7.00e-118	416.00
IUUC-Smo-109423	Selaginella moellendorffii	44.95	3.00e-78	285.00
IUUC-Sar-113262	Sorex araneus	58.19	9.00e-130	456.00
IUUC-Ssc-115392	Sus scrofa	94.93	0.00e+00	667.00
IUUC-Tgu-117340	Taeniopygia guttata	75.27	2.00e-167	581.00
IUUC-Tru-117577	Takifugu rubripes	73.18	7.00e-138	483.00
IUUC-Tsy-119404	Tarsius syrichta	79.95	0.00e+00	663.00
IUUC-Tni-120713	Tetraodon nigroviridis	73.74	7.00e-137	480.00
IUUC-Tbe-127788	Tupaia belangeri	67.49	2.00e-139	488.00
IUUC-Ttr-128608	Tursiops truncatus	82.68	0.00e+00	657.00
IUUC-Xtr-132720	Xenopus tropicalis	59.78	6.00e-148	517.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence