iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000035187.6	ENSDART00000148626.2	ENSDARP00000124744.1
ENSDARG00000035187.6	ENSDART00000149910.1	ENSDARP00000125008.1
ENSDARG00000035187.6	ENSDART00000005516.7	ENSDARP00000017269.7

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.90e-14	52.9	77	134

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++++++W+++  ++++ +G +P+n+++ ++
   Q: 77   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNHNGEWCEA--QTKNGQGWVPSNYITPVN 134
           68899************************.***********..79999**********997 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MGQQPGKLVG EQRRPSLPAL PFIKAAGRRE TPRHGAPHCN VFTVHESRPD FDPPGLSEAA 60
RWNSKENLLS GPSENDPNLF VALYDFVASG DNTLSITKGE KLRVLGYNHN GEWCEAQTKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAGC AGCCAGGAAA GTTAGTGGGT GAGCAGAGGA GACCGAGCCT GCCGGCACTG 60
CCCTTCATCA AGGCCGCGGG GAGGAGAGAG ACGCCCCGGC ACGGAGCACC GCACTGCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0032956--P:regulation of actin cytoskeleton organization

KEGG

dre:100000720

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	72.43	0.00e+00	1139.00
IUUC-Atr-002778	Amborella trichopoda	32.99	5.00e-23	103.00
IUUC-Apl-003452	Anas platyrhynchos	68.24	0.00e+00	1238.00
IUUC-Aca-005312	Anolis carolinensis	74.39	0.00e+00	1045.00
IUUC-Ame-011903	Astyanax mexicanus	77.42	0.00e+00	1473.00
IUUC-Bta-012351	Bos taurus	76.19	0.00e+00	1070.00
IUUC-Cja-019491	Callithrix jacchus	68.59	0.00e+00	1308.00
IUUC-Cfa-021256	Canis familiaris	72.45	0.00e+00	1158.00
IUUC-Cpo-022046	Cavia porcellus	73.65	0.00e+00	1158.00
IUUC-Csa-023046	Chlorocebus sabaeus	68.10	0.00e+00	1261.00
IUUC-Dno-029853	Dasypus novemcinctus	67.99	0.00e+00	1318.00
IUUC-Dor-030635	Dipodomys ordii	69.01	0.00e+00	1013.00
IUUC-Dme-032098	Drosophila melanogaster	74.25	0.00e+00	763.00
IUUC-Eca-033720	Equus caballus	67.15	0.00e+00	1231.00
IUUC-Eeu-035173	Erinaceus europaeus	72.32	0.00e+00	1078.00
IUUC-Fca-035967	Felis catus	72.18	0.00e+00	1135.00
IUUC-Fal-036723	Ficedula albicollis	68.45	0.00e+00	1243.00
IUUC-Gmo-039550	Gadus morhua	81.10	0.00e+00	1173.00
IUUC-Gga-040481	Gallus gallus	84.24	0.00e+00	1012.00
IUUC-Gac-041643	Gasterosteus aculeatus	71.99	0.00e+00	1416.00
IUUC-Ggo-045299	Gorilla gorilla	68.18	0.00e+00	1325.00
IUUC-Hsa-047033	Homo sapiens	95.38	8.00e-35	137.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	66.55	0.00e+00	1229.00
IUUC-Lch-050530	Latimeria chalumnae	73.25	0.00e+00	1171.00
IUUC-Loc-052430	Lepisosteus oculatus	84.39	0.00e+00	1009.00
IUUC-Laf-053609	Loxodonta africana	66.70	0.00e+00	1283.00
IUUC-Mcc-055654	Macaca mulatta	68.58	0.00e+00	1342.00
IUUC-Meu-056488	Macropus eugenii	64.29	0.00e+00	949.00
IUUC-Mga-059270	Meleagris gallopavo	67.81	0.00e+00	1253.00
IUUC-Mmr-060593	Microcebus murinus	72.08	0.00e+00	1092.00
IUUC-Mdo-062227	Monodelphis domestica	78.03	0.00e+00	1093.00
IUUC-Mmu-064002	Mus musculus	75.64	0.00e+00	1176.00
IUUC-Mac-065247	Musa acuminata	30.43	2.00e-22	100.00
IUUC-Mpu-066197	Mustela putorius furo	71.44	0.00e+00	1140.00
IUUC-Mlu-067255	Myotis lucifugus	72.83	0.00e+00	1072.00
IUUC-Nle-069977	Nomascus leucogenys	63.31	0.00e+00	1164.00
IUUC-Opr-070327	Ochotona princeps	70.65	0.00e+00	945.00
IUUC-Ont-072307	Oreochromis niloticus	71.21	0.00e+00	1388.00
IUUC-Oan-073100	Ornithorhynchus anatinus	76.20	0.00e+00	1100.00
IUUC-Ocu-074892	Oryctolagus cuniculus	73.16	0.00e+00	996.00
IUUC-Ola-087389	Oryzias latipes	68.68	0.00e+00	1337.00
IUUC-Oga-088145	Otolemur garnettii	69.02	0.00e+00	1239.00
IUUC-Oar-090432	Ovis aries	76.04	0.00e+00	1061.00
IUUC-Ptr-090800	Pan troglodytes	68.59	0.00e+00	1332.00
IUUC-Psi-093078	Pelodiscus sinensis	69.68	0.00e+00	1274.00
IUUC-Pma-094420	Petromyzon marinus	78.12	0.00e+00	868.00
IUUC-Pfo-096979	Poecilia formosa	75.57	0.00e+00	1145.00
IUUC-Pca-100874	Procavia capensis	93.42	0.00e+00	719.00
IUUC-Pva-102415	Pteropus vampyrus	74.17	0.00e+00	1132.00
IUUC-Rno-105682	Rattus norvegicus	67.93	0.00e+00	1325.00
IUUC-Sha-106711	Sarcophilus harrisii	72.52	0.00e+00	1098.00
IUUC-Ssc-115472	Sus scrofa	75.63	0.00e+00	1142.00
IUUC-Tgu-117037	Taeniopygia guttata	68.22	0.00e+00	1321.00
IUUC-Tru-118324	Takifugu rubripes	72.92	0.00e+00	1204.00
IUUC-Tsy-119216	Tarsius syrichta	89.67	0.00e+00	1043.00
IUUC-Tni-119950	Tetraodon nigroviridis	64.78	0.00e+00	1214.00
IUUC-Ttr-128209	Tursiops truncatus	73.01	0.00e+00	1167.00
IUUC-Xtr-132477	Xenopus tropicalis	68.91	0.00e+00	966.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence