iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088388

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03124022

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000012344.2	ENSOGAT00000012348.2	ENSOGAP00000011046.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.00e-40	133.8	11	43
E3 activity/RING/U-box	1.80e-25	88.8	404	475
UBD/Beta-Prp	3.20e-52	177.6	7	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+af    ll+++s D+t+++++l++++
   Q: 11   HGDDVNCCAFsV-SLLATCSLDKTVRLYSLSDFT 43
           9*********51.6***************98876 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+ef+CpI+ elM+dPv++++G++y+r+++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  MPDEFICPITRELMTDPVIASDGYSYEREAMESWISKKKRTSPMTNLVLPSLVLTPNRTLKMAINRWLETHQ 475
           79*******************************************************************997 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  + sllat s d+t++++++++ +    + l+ h+ +v  ++fsp+g il+++s+D+t  +w+ ++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SVSLLATCSLDKTVRLYSLSDFTElpHSPLKFHTYAVHYCCFSPSGHILASCSTDGTTVLWNTQNGQILAVM 92
           566666655.55889..9*******************9666667889****************************************** PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++ +++sG +d t+ +w+ ++ + ++ + s++dg+    +++pdgnl+v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCQFSPDSTYVASGAADGTLVLWNAQSHKLYR-CGSVKDGSLVACAFSPDGNLFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           9765267**********************************.**********************************8.6678888877. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           h+  +++ +f+s+           ++l+s+++d +vk+w ++
   Q: 179  HDLGITCCDFSSQPvldgeqslqfFRLASCGQDCQVKIWLVS 220
           *********99988999999*******************766 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SVSLLATCSL DKTVRLYSLS DFTELPHSPL KFHTYAVHYC 60
CFSPSGHILA SCSTDGTTVL WNTQNGQILA VMEQPSGSPV RVCQFSPDST YVASGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGGCTGT TTTACTTCCA ATAAAGAACA TGGTGAAACT AATTCACACG TTAGCTGATC 60
ATGGTGATGA TGTCAACTGC TGTGCCTTCT CCGTTTCCCT TTTGGCTACT TGCTCCTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	88.87	0.00e+00	893.00
IUUC-Apl-003529	Anas platyrhynchos	74.16	0.00e+00	751.00
IUUC-Aca-004257	Anolis carolinensis	68.99	0.00e+00	693.00
IUUC-Ame-011357	Astyanax mexicanus	51.67	2.00e-115	409.00
IUUC-Bta-013032	Bos taurus	85.53	0.00e+00	857.00
IUUC-Cja-018743	Callithrix jacchus	90.55	0.00e+00	901.00
IUUC-Cfa-021197	Canis familiaris	88.03	0.00e+00	889.00
IUUC-Cpo-022279	Cavia porcellus	87.39	0.00e+00	877.00
IUUC-Csa-023954	Chlorocebus sabaeus	90.97	0.00e+00	907.00
IUUC-Cho-025083	Choloepus hoffmanni	71.69	2.00e-153	535.00
IUUC-Cin-025786	Ciona intestinalis	35.69	7.00e-83	301.00
IUUC-Dre-028087	Danio rerio	55.76	2.00e-141	495.00
IUUC-Dno-028919	Dasypus novemcinctus	88.87	0.00e+00	891.00
IUUC-Dor-031112	Dipodomys ordii	85.71	0.00e+00	856.00
IUUC-Ete-032405	Echinops telfairi	86.88	0.00e+00	626.00
IUUC-Eca-033254	Equus caballus	88.03	0.00e+00	875.00
IUUC-Eeu-034545	Erinaceus europaeus	83.82	0.00e+00	807.00
IUUC-Fca-035482	Felis catus	89.71	0.00e+00	897.00
IUUC-Fal-036976	Ficedula albicollis	60.46	8.00e-161	560.00
IUUC-Gmo-039213	Gadus morhua	55.04	2.00e-136	478.00
IUUC-Gga-040561	Gallus gallus	72.33	0.00e+00	734.00
IUUC-Gac-041471	Gasterosteus aculeatus	58.19	4.00e-142	498.00
IUUC-Ggo-045503	Gorilla gorilla	90.97	0.00e+00	906.00
IUUC-Hsa-045910	Homo sapiens	90.97	0.00e+00	907.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	88.86	0.00e+00	695.00
IUUC-Loc-052307	Lepisosteus oculatus	59.60	2.00e-167	582.00
IUUC-Laf-053587	Loxodonta africana	88.45	0.00e+00	891.00
IUUC-Mcc-055679	Macaca mulatta	90.76	0.00e+00	906.00
IUUC-Meu-055962	Macropus eugenii	69.75	0.00e+00	645.00
IUUC-Mga-059652	Meleagris gallopavo	72.33	0.00e+00	737.00
IUUC-Mmr-060943	Microcebus murinus	90.17	0.00e+00	890.00
IUUC-Mdo-062592	Monodelphis domestica	79.75	0.00e+00	811.00
IUUC-Mmu-063577	Mus musculus	80.46	0.00e+00	801.00
IUUC-Mpu-066422	Mustela putorius furo	88.24	0.00e+00	882.00
IUUC-Mlu-067250	Myotis lucifugus	89.08	0.00e+00	885.00
IUUC-Nle-069517	Nomascus leucogenys	90.97	0.00e+00	908.00
IUUC-Opr-070776	Ochotona princeps	86.13	0.00e+00	851.00
IUUC-Ont-071821	Oreochromis niloticus	57.32	7.00e-151	526.00
IUUC-Oan-073706	Ornithorhynchus anatinus	80.21	0.00e+00	809.00
IUUC-Ocu-074766	Oryctolagus cuniculus	80.42	0.00e+00	779.00
IUUC-Ola-086531	Oryzias latipes	57.26	9.00e-148	516.00
IUUC-Oar-089748	Ovis aries	86.37	0.00e+00	860.00
IUUC-Ptr-090616	Pan troglodytes	90.70	0.00e+00	899.00
IUUC-Pan-091769	Papio anubis	90.12	0.00e+00	647.00
IUUC-Psi-093334	Pelodiscus sinensis	76.89	0.00e+00	725.00
IUUC-Pma-094383	Petromyzon marinus	48.92	2.00e-134	472.00
IUUC-Pfo-096832	Poecilia formosa	53.43	1.00e-140	492.00
IUUC-Pab-098139	Pongo abelii	89.20	0.00e+00	724.00
IUUC-Pca-100523	Procavia capensis	73.95	0.00e+00	718.00
IUUC-Pva-102286	Pteropus vampyrus	87.61	0.00e+00	852.00
IUUC-Rno-104831	Rattus norvegicus	81.93	0.00e+00	817.00
IUUC-Sha-107499	Sarcophilus harrisii	82.35	0.00e+00	833.00
IUUC-Sar-113389	Sorex araneus	84.24	0.00e+00	815.00
IUUC-Tgu-116769	Taeniopygia guttata	71.22	0.00e+00	714.00
IUUC-Tru-118774	Takifugu rubripes	53.50	2.00e-137	482.00
IUUC-Tsy-119595	Tarsius syrichta	78.40	0.00e+00	629.00
IUUC-Tni-119850	Tetraodon nigroviridis	57.47	2.00e-146	512.00
IUUC-Tbe-127938	Tupaia belangeri	78.36	1.00e-140	492.00
IUUC-Ttr-128193	Tursiops truncatus	87.26	0.00e+00	739.00
IUUC-Vpa-130275	Vicugna pacos	89.50	0.00e+00	894.00
IUUC-Xtr-131982	Xenopus tropicalis	62.11	1.00e-172	599.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence