iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019780

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01049848

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000014721.1	ENSCJAT00000028657.1	ENSCJAP00000027105.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	95.33	0.00e+00	688.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MWATCCNWFC LDGQPEEVPP PQGARMQAYS NPGYSSFPSP TGSEPSCKSC GAHFANTARK 60
QTCLDCKKHF CMTCSSQVGN GPRLCLLCQR FRATAFQREE LMKMKVKDLR DYLSLHDIST 120

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Nucleotide Sequence
(Fasta)

CCCGGCCGGC GGCCGCAGCA GGTGAGGAGG CGGAGGCGGC AGCGCTGGGG ACCGTGGGGC 60
GCCCGGCCTG GGGAATGACG GGAAGGGGGG CGCTCGGGTG CCGCCAGGCT GTGGTCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cjc:100895959

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	89.56	0.00e+00	634.00
IUUC-Apl-004124	Anas platyrhynchos	64.75	1.00e-121	429.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	1.00e-08	55.50
IUUC-Ame-011616	Astyanax mexicanus	57.92	8.00e-106	376.00
IUUC-Bta-012374	Bos taurus	84.89	5.00e-176	610.00
IUUC-Cfa-021252	Canis familiaris	90.66	0.00e+00	635.00
IUUC-Cpo-022047	Cavia porcellus	89.84	0.00e+00	652.00
IUUC-Csa-023161	Chlorocebus sabaeus	95.33	0.00e+00	696.00
IUUC-Cho-024316	Choloepus hoffmanni	87.83	1.00e-150	525.00
IUUC-Dre-028596	Danio rerio	55.22	6.00e-107	380.00
IUUC-Dno-029333	Dasypus novemcinctus	90.11	0.00e+00	652.00
IUUC-Ete-033163	Echinops telfairi	83.24	2.00e-166	578.00
IUUC-Eca-033994	Equus caballus	90.38	0.00e+00	659.00
IUUC-Eeu-035162	Erinaceus europaeus	85.05	7.00e-129	452.00
IUUC-Fca-036418	Felis catus	89.01	0.00e+00	657.00
IUUC-Fal-037427	Ficedula albicollis	64.67	3.00e-127	448.00
IUUC-Gga-041053	Gallus gallus	66.21	6.00e-126	443.00
IUUC-Ggo-045436	Gorilla gorilla	95.33	0.00e+00	697.00
IUUC-Hsa-045798	Homo sapiens	95.33	0.00e+00	697.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	89.84	0.00e+00	635.00
IUUC-Lch-050639	Latimeria chalumnae	61.81	6.00e-122	430.00
IUUC-Laf-053355	Loxodonta africana	87.70	1.00e-178	619.00
IUUC-Mcc-055222	Macaca mulatta	95.88	0.00e+00	677.00
IUUC-Meu-056692	Macropus eugenii	76.92	6.00e-157	546.00
IUUC-Mga-059298	Meleagris gallopavo	66.21	1.00e-125	442.00
IUUC-Mmr-061792	Microcebus murinus	90.11	0.00e+00	635.00
IUUC-Mdo-062986	Monodelphis domestica	79.95	2.00e-162	565.00
IUUC-Mmu-063356	Mus musculus	86.81	3.00e-180	624.00
IUUC-Mpu-066273	Mustela putorius furo	90.11	0.00e+00	665.00
IUUC-Mlu-066953	Myotis lucifugus	89.29	0.00e+00	647.00
IUUC-Nle-070075	Nomascus leucogenys	95.05	0.00e+00	694.00
IUUC-Opr-070838	Ochotona princeps	87.36	2.00e-180	624.00
IUUC-Ont-071967	Oreochromis niloticus	74.13	6.00e-56	211.00
IUUC-Ocu-074807	Oryctolagus cuniculus	88.74	0.00e+00	648.00
IUUC-Obr-076159	Oryza brachyantha	41.07	4.00e-08	50.40
IUUC-Ola-086903	Oryzias latipes	66.89	5.00e-55	207.00
IUUC-Oga-088536	Otolemur garnettii	89.84	4.00e-179	620.00
IUUC-Oar-089838	Ovis aries	85.71	9.00e-177	612.00
IUUC-Ptr-090962	Pan troglodytes	95.05	0.00e+00	697.00
IUUC-Pan-092853	Papio anubis	94.78	0.00e+00	691.00
IUUC-Psi-093164	Pelodiscus sinensis	63.93	2.00e-123	435.00
IUUC-Pma-094104	Petromyzon marinus	45.25	3.00e-55	208.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	55.80
IUUC-Pab-098304	Pongo abelii	95.88	0.00e+00	698.00
IUUC-Pca-100316	Procavia capensis	88.19	6.00e-177	613.00
IUUC-Ppe-101490	Prunus persica	37.80	2.00e-09	57.00
IUUC-Pva-102612	Pteropus vampyrus	75.55	3.00e-151	527.00
IUUC-Rno-105449	Rattus norvegicus	87.64	4.00e-180	623.00
IUUC-Sha-107578	Sarcophilus harrisii	79.12	2.00e-154	538.00
IUUC-Sar-113638	Sorex araneus	85.44	3.00e-176	610.00
IUUC-Ssc-116401	Sus scrofa	87.91	0.00e+00	653.00
IUUC-Tru-118765	Takifugu rubripes	48.14	9.00e-80	290.00
IUUC-Tsy-118850	Tarsius syrichta	88.16	8.00e-150	522.00
IUUC-Tbe-128086	Tupaia belangeri	82.14	4.00e-169	587.00
IUUC-Ttr-128249	Tursiops truncatus	68.13	2.00e-137	481.00
IUUC-Vpa-130816	Vicugna pacos	84.88	1.00e-39	156.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence