iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000020696.18	ENSMUST00000021036.12	ENSMUSP00000021036.6
ENSMUSG00000020696.18	ENSMUST00000103218.2	ENSMUSP00000099507.2
ENSMUSG00000020696.18	ENSMUST00000093975.11	ENSMUSP00000091510.5
ENSMUSG00000020696.18	ENSMUST00000071152.13	ENSMUSP00000071150.7

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	miRNAMap	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	89.53	0.00e+00	650.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Protein Sequence
(Fasta)

MISSEHGSSD LSRSFFGQPT VCCGSVLRQA KADFIMWASC CNWFCLDGQP EEAPPPQGAR 60
TQAYSNPGYS SFPSPTGSEP SCKACGVHFA STTRKQTCLD CKKNFCMTCS SQEGNGPRLC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCCCACG CCGAGCCGCG GGGGACTGGG TTAGTGGGGG TGGACTTCCT GGGGCCGCCC 60
GTGAGGATGT GGTTCGGGCA CCCGGGCGCC CCTCAGGCGT GGAGTTGCGG CGGCCGCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	86.38	1.00e-176	612.00
IUUC-Apl-004124	Anas platyrhynchos	66.03	3.00e-122	431.00
IUUC-Ame-011616	Astyanax mexicanus	58.86	4.00e-103	367.00
IUUC-Bta-012374	Bos taurus	84.18	0.00e+00	625.00
IUUC-Cja-019780	Callithrix jacchus	86.81	0.00e+00	632.00
IUUC-Cfa-021252	Canis familiaris	89.07	3.00e-179	620.00
IUUC-Cpo-022047	Cavia porcellus	88.80	0.00e+00	640.00
IUUC-Csa-023161	Chlorocebus sabaeus	88.43	0.00e+00	667.00
IUUC-Cho-024316	Choloepus hoffmanni	86.47	3.00e-145	507.00
IUUC-Cne-026858	Cryptococcus neoformans	25.75	3.00e-07	49.70
IUUC-Dre-028596	Danio rerio	56.20	8.00e-109	386.00
IUUC-Dno-029333	Dasypus novemcinctus	89.53	0.00e+00	633.00
IUUC-Ete-033163	Echinops telfairi	79.61	1.00e-158	551.00
IUUC-Eca-033994	Equus caballus	89.34	0.00e+00	645.00
IUUC-Eeu-035162	Erinaceus europaeus	82.00	1.00e-119	422.00
IUUC-Fca-036418	Felis catus	87.98	0.00e+00	673.00
IUUC-Fal-037427	Ficedula albicollis	64.85	3.00e-129	455.00
IUUC-Gga-041053	Gallus gallus	68.32	9.00e-132	462.00
IUUC-Ggo-045436	Gorilla gorilla	89.53	0.00e+00	676.00
IUUC-Hsa-045798	Homo sapiens	89.53	0.00e+00	676.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	86.22	0.00e+00	651.00
IUUC-Lch-050639	Latimeria chalumnae	61.71	2.00e-125	442.00
IUUC-Laf-053355	Loxodonta africana	87.26	6.00e-177	613.00
IUUC-Mcc-055222	Macaca mulatta	88.15	3.00e-180	624.00
IUUC-Meu-056692	Macropus eugenii	77.69	9.00e-156	542.00
IUUC-Mga-059298	Meleagris gallopavo	67.12	2.00e-131	462.00
IUUC-Mmr-061792	Microcebus murinus	85.40	4.00e-176	610.00
IUUC-Mdo-062986	Monodelphis domestica	76.38	5.00e-171	593.00
IUUC-Mpu-066273	Mustela putorius furo	87.98	0.00e+00	667.00
IUUC-Mlu-066953	Myotis lucifugus	87.70	0.00e+00	654.00
IUUC-Nle-070075	Nomascus leucogenys	89.07	0.00e+00	682.00
IUUC-Opr-070838	Ochotona princeps	85.67	1.00e-175	608.00
IUUC-Ont-071967	Oreochromis niloticus	52.89	2.00e-92	332.00
IUUC-Ocu-074807	Oryctolagus cuniculus	86.89	0.00e+00	655.00
IUUC-Obr-076159	Oryza brachyantha	41.07	5.00e-08	50.40
IUUC-Ola-086903	Oryzias latipes	47.69	3.00e-91	328.00
IUUC-Oga-088536	Otolemur garnettii	86.50	6.00e-173	600.00
IUUC-Oar-089838	Ovis aries	84.47	6.00e-175	606.00
IUUC-Ptr-090962	Pan troglodytes	89.81	0.00e+00	677.00
IUUC-Pan-092853	Papio anubis	87.88	0.00e+00	664.00
IUUC-Psi-093164	Pelodiscus sinensis	70.14	4.00e-125	441.00
IUUC-Pma-094104	Petromyzon marinus	45.03	6.00e-56	211.00
IUUC-Pab-098304	Pongo abelii	88.80	0.00e+00	676.00
IUUC-Pca-100316	Procavia capensis	86.78	2.00e-172	598.00
IUUC-Ppe-101490	Prunus persica	36.59	2.00e-09	57.00
IUUC-Pva-102612	Pteropus vampyrus	74.38	9.00e-150	523.00
IUUC-Rno-105449	Rattus norvegicus	97.80	0.00e+00	705.00
IUUC-Sha-107578	Sarcophilus harrisii	79.45	1.00e-153	535.00
IUUC-Sar-113638	Sorex araneus	83.47	4.00e-168	583.00
IUUC-Ssc-116401	Sus scrofa	87.77	0.00e+00	665.00
IUUC-Tru-118765	Takifugu rubripes	49.05	1.00e-81	296.00
IUUC-Tsy-118850	Tarsius syrichta	85.15	3.00e-143	500.00
IUUC-Tbe-128086	Tupaia belangeri	80.99	1.00e-171	595.00
IUUC-Ttr-128249	Tursiops truncatus	79.62	5.00e-90	324.00
IUUC-Vpa-130816	Vicugna pacos	87.21	6.00e-41	160.00
IUUC-Xtr-132262	Xenopus tropicalis	41.41	3.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence