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Tag Content
iUUCD ID IUUC-Gga-041107
Ensembl Protein ID ENSGALP00000023934.4
UniProt Accession P09324; YES_CHICK
Genbank Protein ID CAA31002.1; CAA31595.1; CAA49365.1
Protein Name Tyrosine-protein kinase Yes; p61-Yes
Genbank Nucleotide ID X12461; X13207; X69695
Gene Name YES1; YES
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000014860.5 ENSGALT00000023980.5 ENSGALP00000023934.4
ENSGALG00000014860.5 ENSGALT00000064616.1 ENSGALP00000050000.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.70e-15 56.4 94 149
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L++kkG+  ++i  ++++++W+++ + ++gk G +P+n+v+ ++
   Q: 94   FVALYDYEARTTDDLSFKKGERFQII--NNTEGDWWEARSIATGKTGYIPSNYVAPAD 149
           789***********************..8999**********************9875 PP
   
Organism Gallus gallus
Functional Description
(View)

Functional Description


     Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis.
 Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytokinesis.
Protein Sequence
(Fasta)
MGCIKSKEDK GPAMKYRTDN TPEPISSHVS HYGSDSSQAT QSPAIKGSAV NFNSHSMTPF 60
GGPSGMTPFG GASSSFSAVP SPYPSTLTGG VTVFVALYDY EARTTDDLSF KKGERFQIIN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-041107|UBD,SH3|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCCCCCCCTT CCCTCCCCGG GTCGCCGCGG CTCCGGGAGG AGCGGGGGGG GCCCCGCTTC 60
CTTCCCTCTC CCCCTCCTTC TCCCACCCGC GCCGCCGAGG ACGGGCAGGT GAGCACCCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-041107|UBD,SH3|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0418--Kinase
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0519--Myristate
KW-0547--Nucleotide-binding
KW-0564--Palmitate
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE
SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005884--C:actin filament
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005815--C:microtubule organizing center
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0036120--P:cellular response to platelet-derived growth factor stimulus
GO:0071300--P:cellular response to retinoic acid
GO:0071560--P:cellular response to transforming growth factor beta stimulus
GO:0048013--P:ephrin receptor signaling pathway
GO:0015758--P:glucose transport
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
KEGG gga:396238
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002374 Ailuropoda melanoleuca 92.25 0.00e+00 1021.00
IUUC-Apl-004032 Anas platyrhynchos 99.63 0.00e+00 1100.00
IUUC-Aca-004255 Anolis carolinensis 94.64 0.00e+00 1081.00
IUUC-Ame-010954 Astyanax mexicanus 88.12 0.00e+00 1006.00
IUUC-Bta-013503 Bos taurus 91.13 0.00e+00 991.00
IUUC-Cel-018682 Caenorhabditis elegans 58.17 3.00e-150 525.00
IUUC-Cja-019694 Callithrix jacchus 91.53 0.00e+00 1003.00
IUUC-Cfa-020402 Canis familiaris 92.05 0.00e+00 1019.00
IUUC-Cpo-022506 Cavia porcellus 92.42 0.00e+00 1021.00
IUUC-Csa-023713 Chlorocebus sabaeus 92.27 0.00e+00 1013.00
IUUC-Cin-025390 Ciona intestinalis 71.64 0.00e+00 667.00
IUUC-Csv-026029 Ciona savignyi 63.98 0.00e+00 645.00
IUUC-Dre-027978 Danio rerio 86.63 0.00e+00 972.00
IUUC-Dno-029897 Dasypus novemcinctus 90.76 0.00e+00 910.00
IUUC-Dor-030202 Dipodomys ordii 95.58 0.00e+00 914.00
IUUC-Eca-034157 Equus caballus 91.50 0.00e+00 1014.00
IUUC-Eeu-034950 Erinaceus europaeus 88.64 8.00e-174 602.00
IUUC-Fca-036233 Felis catus 92.05 0.00e+00 1057.00
IUUC-Fal-037461 Ficedula albicollis 98.52 0.00e+00 1117.00
IUUC-Gmo-038929 Gadus morhua 84.34 0.00e+00 922.00
IUUC-Gac-042321 Gasterosteus aculeatus 85.43 0.00e+00 956.00
IUUC-Hsa-047010 Homo sapiens 91.90 0.00e+00 1017.00
IUUC-Lch-050239 Latimeria chalumnae 91.87 0.00e+00 1043.00
IUUC-Loc-052314 Lepisosteus oculatus 90.46 0.00e+00 979.00
IUUC-Laf-053517 Loxodonta africana 92.05 0.00e+00 999.00
IUUC-Mcc-055626 Macaca mulatta 92.27 0.00e+00 1013.00
IUUC-Mga-059310 Meleagris gallopavo 100.00 0.00e+00 1103.00
IUUC-Mmr-061652 Microcebus murinus 91.87 0.00e+00 1016.00
IUUC-Mdo-062963 Monodelphis domestica 91.68 0.00e+00 1029.00
IUUC-Mmu-064128 Mus musculus 90.94 0.00e+00 1025.00
IUUC-Mpu-065906 Mustela putorius furo 92.42 0.00e+00 1024.00
IUUC-Mlu-067035 Myotis lucifugus 92.46 0.00e+00 1022.00
IUUC-Nle-069041 Nomascus leucogenys 87.85 0.00e+00 958.00
IUUC-Opr-070299 Ochotona princeps 82.99 0.00e+00 891.00
IUUC-Ont-072337 Oreochromis niloticus 87.39 0.00e+00 980.00
IUUC-Oan-072997 Ornithorhynchus anatinus 98.03 0.00e+00 940.00
IUUC-Ocu-074171 Oryctolagus cuniculus 92.24 0.00e+00 1024.00
IUUC-Oba-075994 Oryza barthii 34.98 2.00e-21 97.40
IUUC-Ola-086619 Oryzias latipes 84.39 0.00e+00 973.00
IUUC-Oga-087957 Otolemur garnettii 91.68 0.00e+00 1008.00
IUUC-Oar-089670 Ovis aries 90.02 0.00e+00 1009.00
IUUC-Ptr-091352 Pan troglodytes 91.90 0.00e+00 1017.00
IUUC-Pan-092202 Papio anubis 92.27 0.00e+00 1013.00
IUUC-Psi-093310 Pelodiscus sinensis 97.23 0.00e+00 1107.00
IUUC-Pma-094232 Petromyzon marinus 86.23 0.00e+00 864.00
IUUC-Pfo-096137 Poecilia formosa 84.09 0.00e+00 956.00
IUUC-Pab-098301 Pongo abelii 96.08 0.00e+00 946.00
IUUC-Pva-102592 Pteropus vampyrus 87.80 0.00e+00 962.00
IUUC-Rno-105544 Rattus norvegicus 90.94 0.00e+00 998.00
IUUC-Sar-113364 Sorex araneus 88.54 0.00e+00 949.00
IUUC-Tgu-117380 Taeniopygia guttata 98.52 0.00e+00 1117.00
IUUC-Tru-117784 Takifugu rubripes 85.37 0.00e+00 965.00
IUUC-Tni-120433 Tetraodon nigroviridis 84.99 0.00e+00 954.00
IUUC-Ttr-128893 Tursiops truncatus 91.68 0.00e+00 1014.00
IUUC-Vpa-130060 Vicugna pacos 92.24 0.00e+00 1014.00
IUUC-Xtr-132322 Xenopus tropicalis 93.16 0.00e+00 1049.00
Created Date 25-Jun-2017

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