iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044900

Ensembl Protein ID

ENSGGOP00000001842.2

UniProt Accession

G3QHL2; G3QHL2_GORGO

Protein Name

Uncharacterized protein

Gene Name

ARHGEF37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001871.2	ENSGGOT00000001883.2	ENSGGOP00000001842.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.70e-11	42.4	605	664

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++v++ y++ a ++ e +l++G  v+++  ++++ + +W     e +g+rG +P+ F ++++
   Q: 605  NQVIAVYPFVARSSHEVSLQAGQPVTILeaQDKKGNPEWSLV--EVNGQRGYVPSGFLARAR 664
           789*************************9889999****977..9************99875 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAKHGADEPS SRSGSPDGEG RASEDRSLLH QRLAVRELID TEVSYLHMLQ LCASDIRSRL 60
QQLPQGDLDV LFSNIDDIIK VNSRFLHDLQ ETASKEEEQV QLVGNIFLEF QEELEQVYKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGGGCGGC CGACCTCCGT GCGTGAGCGC CGGCAGGCAC CTTGCGCGCG CGGGTGAGTC 60
CGCTGGGCGT TTGGGGCCTG GTCAAGCAGG ATGGGGCTGG AGAGGGGTGC AGGAAACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

ggo:101148889

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	29.20	3.00e-66	247.00
IUUC-Apl-003698	Anas platyrhynchos	32.40	4.00e-81	295.00
IUUC-Aca-005005	Anolis carolinensis	29.75	6.00e-67	249.00
IUUC-Ame-011907	Astyanax mexicanus	39.59	1.00e-127	450.00
IUUC-Bta-012848	Bos taurus	86.22	0.00e+00	1121.00
IUUC-Cel-018396	Caenorhabditis elegans	24.03	7.00e-22	100.00
IUUC-Cfa-021281	Canis familiaris	85.19	0.00e+00	1100.00
IUUC-Cpo-022440	Cavia porcellus	30.00	5.00e-66	246.00
IUUC-Csa-023043	Chlorocebus sabaeus	96.44	0.00e+00	1282.00
IUUC-Dre-028496	Danio rerio	39.29	5.00e-125	441.00
IUUC-Dno-029750	Dasypus novemcinctus	29.88	8.00e-66	246.00
IUUC-Ete-032921	Echinops telfairi	63.79	2.00e-73	268.00
IUUC-Eca-033433	Equus caballus	30.65	4.00e-67	250.00
IUUC-Eeu-034929	Erinaceus europaeus	31.60	3.00e-38	154.00
IUUC-Fca-035859	Felis catus	29.32	2.00e-66	248.00
IUUC-Fal-036653	Ficedula albicollis	29.03	4.00e-61	230.00
IUUC-Gmo-038948	Gadus morhua	28.25	2.00e-66	247.00
IUUC-Gga-040279	Gallus gallus	29.32	2.00e-65	244.00
IUUC-Gac-041641	Gasterosteus aculeatus	29.98	1.00e-70	262.00
IUUC-Hsa-045684	Homo sapiens	98.37	0.00e+00	1333.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	29.04	7.00e-61	229.00
IUUC-Lch-050096	Latimeria chalumnae	46.10	6.00e-168	584.00
IUUC-Loc-051937	Lepisosteus oculatus	42.27	1.00e-133	470.00
IUUC-Mcc-054950	Macaca mulatta	96.00	0.00e+00	1276.00
IUUC-Meu-056383	Macropus eugenii	69.45	3.00e-173	602.00
IUUC-Mga-059868	Meleagris gallopavo	29.02	4.00e-62	234.00
IUUC-Mmr-060767	Microcebus murinus	30.36	4.00e-64	240.00
IUUC-Mdo-062021	Monodelphis domestica	68.06	0.00e+00	880.00
IUUC-Mmu-064186	Mus musculus	79.29	0.00e+00	1028.00
IUUC-Mpu-065913	Mustela putorius furo	29.66	7.00e-67	249.00
IUUC-Mlu-067340	Myotis lucifugus	30.36	4.00e-65	244.00
IUUC-Opr-070694	Ochotona princeps	28.38	4.00e-59	223.00
IUUC-Ont-071844	Oreochromis niloticus	28.62	3.00e-69	258.00
IUUC-Ocu-074406	Oryctolagus cuniculus	30.02	2.00e-64	241.00
IUUC-Ola-087343	Oryzias latipes	30.76	2.00e-88	319.00
IUUC-Oga-088847	Otolemur garnettii	30.05	2.00e-64	241.00
IUUC-Oar-089817	Ovis aries	30.14	8.00e-66	246.00
IUUC-Ptr-090508	Pan troglodytes	98.81	0.00e+00	1302.00
IUUC-Pan-092517	Papio anubis	96.15	0.00e+00	1250.00
IUUC-Pma-094663	Petromyzon marinus	29.24	2.00e-52	201.00
IUUC-Pfo-096703	Poecilia formosa	39.44	1.00e-122	433.00
IUUC-Pab-098542	Pongo abelii	98.37	0.00e+00	1293.00
IUUC-Pva-102490	Pteropus vampyrus	28.38	1.00e-62	235.00
IUUC-Rno-105455	Rattus norvegicus	81.07	0.00e+00	1060.00
IUUC-Sha-106562	Sarcophilus harrisii	69.50	0.00e+00	867.00
IUUC-Ssc-115250	Sus scrofa	30.31	7.00e-66	246.00
IUUC-Tru-118279	Takifugu rubripes	30.36	2.00e-76	281.00
IUUC-Tni-120459	Tetraodon nigroviridis	32.67	3.00e-93	335.00
IUUC-Ttr-128242	Tursiops truncatus	82.37	0.00e+00	1079.00
IUUC-Vpa-130643	Vicugna pacos	27.87	2.00e-55	211.00
IUUC-Xtr-131979	Xenopus tropicalis	29.09	9.00e-65	242.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence