iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107502

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01232399

Gene Name

USP11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000007468.1	ENSSHAT00000008691.1	ENSSHAP00000008620.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.90e-113	376.9	220	873

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ ++ln  np ++kge+++++++l+++ w++++++v pr+++++++++a++f gy+
   Q: 220  CGLTNLGNTCFMNSALQCLSNVPPLTEYFLHnHYLKELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSVVPRMFKTKVGHFASQFLGYQ 308
           7******************************9999****************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++   ++e  dea++++k++n+s+i+d+F+g +ks+++c+ec++vs++++pf++ls+
   Q: 309  QHDSQELLSFLLDGLHEDLNRVKKKEYVELRDAAgrpDQEVADEAWRNHKRRNDSVIVDTFHGLFKSTLVCPECGKVSVTFDPFCYLSV 397
           ***************************99988762114556666********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++e+ +e                                                                              
   Q: 398  PLPVSKERGMEvffvsmdprrkpeqhrlvvpkagkvldlcvalakhtgvspdrmmvadvfshrfykiyqleeslscildrddifvyevs 486
           ******99999****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 487  ggagggegtgedvvlpvylrertpardysdsyyglmlfghpllvsvprdrlswdalyhillhrlsryvtrpesddeeddddddddddee 575
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 576  edddeddddeeeeednseddeeeeeeddeedlykrpsrlsegeedeeeerggstldvrpstegsgatsgvqvglhtvnsngtsdrrgfa 664
           ***************************************************************************************** PP
   S: 186  ..........................................................slqdcLesftkeeelegenkyycekckkkqe 216
                                                                      lq+c+e ft+ e+le+en +yc++ck++q 
   Q: 665  edangvsfncerekeggaqpyiaidwepdmkkryyneveaegyvkhdcmgyvlrkapvRLQECIELFTTVETLEEENPWYCPTCKRHQL 753
           ***************************************************************************************** PP
   S: 217  aekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvknek 303
           a+kkl+l+ lPe Li+hLkRfs+++   srek+++ vefp++ Ld s+f ++p ++ +  ++kY+Liav +H+G+l+ GHY+++++n++
   Q: 754  ATKKLDLWALPEALIIHLKRFSYTK--FSREKLDTLVEFPIRdLDFSEFIIKPRTEADPtPCKYDLIAVSNHYGGLRDGHYTTFARNKD 840
           *********************8866..89*******************9999877654349**************************65 PP
   S: 304  gk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
            + W +fdDs+V++v+e+++++   + aYvlfY+r+
   Q: 841  SGqWHYFDDSSVSPVSESQIES---KAAYVLFYQRQ 873
           545*******************...*********96 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

FLVEQHWYQQ WEAYVRGGDQ DSSAFPGPVN NAELFEDQET WRLKERLVEG EDYVLLPAMA 60
WHLLVNWYGL EPGQPPIERK VVELPSTHKV EVYLVELLLC QHNDMEISRP AQFSRADPVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCAGGCTC TGACCCCTCC CCCTCCCGCT CTGCTCGCCT CCCGCCCCTC CCCCAGGTTC 60
CTGGTGGAAC AACACTGGTA CCAGCAGTGG GAGGCCTATG TCCGAGGTGG AGACCAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	80.07	0.00e+00	895.00
IUUC-Aca-004532	Anolis carolinensis	75.40	0.00e+00	881.00
IUUC-Ago-007911	Ashbya gossypii	39.14	3.00e-63	237.00
IUUC-Afl-008507	Aspergillus flavus	34.93	5.00e-55	209.00
IUUC-Ani-009479	Aspergillus nidulans	42.60	1.00e-51	198.00
IUUC-Ang-009562	Aspergillus niger	44.40	1.00e-54	209.00
IUUC-Aor-009949	Aspergillus oryzae	35.19	4.00e-54	206.00
IUUC-Ate-010323	Aspergillus terreus	36.46	1.00e-54	209.00
IUUC-Ame-011858	Astyanax mexicanus	62.70	0.00e+00	714.00
IUUC-Bta-013284	Bos taurus	81.62	0.00e+00	925.00
IUUC-Cja-019746	Callithrix jacchus	76.12	0.00e+00	876.00
IUUC-Cfa-020134	Canis familiaris	81.15	0.00e+00	919.00
IUUC-Cpo-022535	Cavia porcellus	72.89	0.00e+00	835.00
IUUC-Csa-023828	Chlorocebus sabaeus	76.48	0.00e+00	879.00
IUUC-Dre-027398	Danio rerio	65.65	0.00e+00	758.00
IUUC-Dor-030384	Dipodomys ordii	73.61	0.00e+00	830.00
IUUC-Ete-033029	Echinops telfairi	86.56	3.00e-129	456.00
IUUC-Eca-033271	Equus caballus	80.97	0.00e+00	897.00
IUUC-Fca-036012	Felis catus	79.17	0.00e+00	899.00
IUUC-Fso-038291	Fusarium solani	44.44	8.00e-65	243.00
IUUC-Hsa-046551	Homo sapiens	76.66	0.00e+00	880.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	75.58	0.00e+00	877.00
IUUC-Kpa-049332	Komagataella pastoris	31.72	2.00e-65	244.00
IUUC-Laf-054561	Loxodonta africana	77.92	0.00e+00	889.00
IUUC-Mcc-054881	Macaca mulatta	76.12	0.00e+00	876.00
IUUC-Meu-056749	Macropus eugenii	94.73	0.00e+00	1048.00
IUUC-Mla-058848	Melampsora laricipopulina	41.16	3.00e-69	257.00
IUUC-Mvi-060324	Microbotryum violaceum	31.47	1.00e-75	278.00
IUUC-Mmr-061400	Microcebus murinus	78.28	0.00e+00	892.00
IUUC-Mdo-062470	Monodelphis domestica	93.56	0.00e+00	927.00
IUUC-Mmu-063241	Mus musculus	73.97	0.00e+00	850.00
IUUC-Mpu-066507	Mustela putorius furo	80.79	0.00e+00	915.00
IUUC-Mlu-066961	Myotis lucifugus	76.12	0.00e+00	857.00
IUUC-Nle-069284	Nomascus leucogenys	76.66	0.00e+00	882.00
IUUC-Oan-073387	Ornithorhynchus anatinus	82.23	0.00e+00	905.00
IUUC-Ocu-074066	Oryctolagus cuniculus	75.40	0.00e+00	863.00
IUUC-Oga-088424	Otolemur garnettii	78.10	0.00e+00	895.00
IUUC-Oar-089732	Ovis aries	81.51	0.00e+00	926.00
IUUC-Pan-092292	Papio anubis	76.30	0.00e+00	879.00
IUUC-Pfo-096414	Poecilia formosa	67.62	0.00e+00	776.00
IUUC-Pab-098779	Pongo abelii	66.73	0.00e+00	714.00
IUUC-Pca-100851	Procavia capensis	76.30	0.00e+00	758.00
IUUC-Pva-103244	Pteropus vampyrus	78.82	0.00e+00	891.00
IUUC-Ptt-103847	Puccinia triticina	36.86	8.00e-63	236.00
IUUC-Rno-105100	Rattus norvegicus	73.97	0.00e+00	852.00
IUUC-Sce-106170	Saccharomyces cerevisiae	38.19	5.00e-61	229.00
IUUC-Spo-108291	Schizosaccharomyces pombe	33.16	4.00e-77	282.00
IUUC-Ssc-116345	Sus scrofa	82.23	0.00e+00	932.00
IUUC-Tru-117788	Takifugu rubripes	66.03	0.00e+00	759.00
IUUC-Tsy-119414	Tarsius syrichta	70.66	0.00e+00	790.00
IUUC-Tni-120799	Tetraodon nigroviridis	64.49	0.00e+00	751.00
IUUC-Tre-121888	Trichoderma reesei	44.60	3.00e-63	238.00
IUUC-Tvi-122422	Trichoderma virens	43.01	2.00e-58	221.00
IUUC-Tbe-128081	Tupaia belangeri	76.95	0.00e+00	856.00
IUUC-Ttr-128502	Tursiops truncatus	76.66	0.00e+00	844.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence