iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033582

Ensembl Protein ID

ENSECAP00000021616.1

UniProt Accession

F6X5V7; F6X5V7_HORSE

Protein Name

Uncharacterized protein

Gene Name

TNIP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024134.1	ENSECAT00000025955.1	ENSECAP00000021616.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	2.10e-22	79.0	252	308

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           ++++le+v++L+qQ+ +Yk+DF +ERadREr+++++ eL+e+v++lq+q s+++ds+
   Q: 252  RDAALERVQMLEQQILAYKDDFTSERADRERAQSRIHELEEKVASLQHQASWRQDSR 308
           6899***************************************************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

DQLAGRLALL PRLRVRPAAL EGDAAPSLVD ALLEQVARFL EQLRQQEGGA AEAALRQEIE 60
RLSEQLEEKE RETQQLMSQP EHEREKEVAL LRRSVAEKER ARAASDVLCR SLADETHQLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGTACGGA CCAGCTTGCC GGCCGACTCG CCCTCTTGCC GCGCCTCCGC GTCCGCCCGG 60
CCGCGCTCGA GGGGGACGCG GCCCCGTCGC TCGTGGACGC GCTGCTGGAG CAGGTGGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR022008--EABR
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF12180--EABR

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0023035--P:CD40 signaling pathway
GO:0071222--P:cellular response to lipopolysaccharide
GO:0007249--P:I-kappaB kinase/NF-kappaB signaling
GO:0070498--P:interleukin-1-mediated signaling pathway
GO:2000352--P:negative regulation of endothelial cell apoptotic process
GO:0050871--P:positive regulation of B cell activation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043032--P:positive regulation of macrophage activation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0050821--P:protein stabilization
GO:0034134--P:toll-like receptor 2 signaling pathway
GO:0034138--P:toll-like receptor 3 signaling pathway
GO:0034162--P:toll-like receptor 9 signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001697	Ailuropoda melanoleuca	77.88	8.00e-140	489.00
IUUC-Apl-003896	Anas platyrhynchos	47.38	3.00e-92	332.00
IUUC-Ame-011223	Astyanax mexicanus	34.96	3.00e-45	176.00
IUUC-Bta-012996	Bos taurus	82.44	5.00e-145	506.00
IUUC-Cja-019376	Callithrix jacchus	73.05	3.00e-130	458.00
IUUC-Cfa-021027	Canis familiaris	73.99	6.00e-150	523.00
IUUC-Cpo-021372	Cavia porcellus	68.12	1.00e-106	379.00
IUUC-Csa-023221	Chlorocebus sabaeus	80.49	2.00e-148	518.00
IUUC-Dre-028604	Danio rerio	37.18	4.00e-50	191.00
IUUC-Dno-029976	Dasypus novemcinctus	68.69	2.00e-53	201.00
IUUC-Dor-030364	Dipodomys ordii	58.05	1.00e-57	216.00
IUUC-Eeu-034751	Erinaceus europaeus	69.04	1.00e-62	232.00
IUUC-Fca-036086	Felis catus	80.17	2.00e-136	478.00
IUUC-Fal-036828	Ficedula albicollis	49.88	2.00e-96	346.00
IUUC-Gmo-038838	Gadus morhua	37.98	1.00e-43	170.00
IUUC-Gga-041179	Gallus gallus	50.12	2.00e-91	329.00
IUUC-Gac-042266	Gasterosteus aculeatus	36.86	1.00e-42	167.00
IUUC-Ggo-044971	Gorilla gorilla	81.57	1.00e-148	519.00
IUUC-Hsa-045772	Homo sapiens	81.30	2.00e-145	508.00
IUUC-Itr-048993	Ictidomys tridecemlineatus	74.78	3.00e-120	424.00
IUUC-Lch-049851	Latimeria chalumnae	39.08	7.00e-63	234.00
IUUC-Loc-052551	Lepisosteus oculatus	37.93	8.00e-56	211.00
IUUC-Laf-053650	Loxodonta africana	56.31	7.00e-81	293.00
IUUC-Mcc-054744	Macaca mulatta	80.75	3.00e-151	528.00
IUUC-Meu-056799	Macropus eugenii	56.46	6.00e-35	140.00
IUUC-Mga-060124	Meleagris gallopavo	50.40	2.00e-88	319.00
IUUC-Mmr-061466	Microcebus murinus	78.71	5.00e-131	460.00
IUUC-Mdo-062389	Monodelphis domestica	58.21	7.00e-111	394.00
IUUC-Mmu-064000	Mus musculus	70.91	9.00e-135	473.00
IUUC-Mpu-066109	Mustela putorius furo	80.79	9.00e-158	549.00
IUUC-Mlu-067666	Myotis lucifugus	68.46	1.00e-78	285.00
IUUC-Nle-069689	Nomascus leucogenys	80.13	4.00e-135	473.00
IUUC-Opr-070774	Ochotona princeps	58.28	1.00e-68	252.00
IUUC-Ont-072439	Oreochromis niloticus	40.00	1.00e-60	226.00
IUUC-Oan-072817	Ornithorhynchus anatinus	53.11	1.00e-56	212.00
IUUC-Ocu-074621	Oryctolagus cuniculus	65.89	1.00e-83	303.00
IUUC-Ola-087305	Oryzias latipes	37.56	5.00e-51	195.00
IUUC-Oga-087920	Otolemur garnettii	70.92	2.00e-122	432.00
IUUC-Oar-090351	Ovis aries	69.79	1.00e-20	90.90
IUUC-Ptr-090879	Pan troglodytes	74.06	4.00e-98	350.00
IUUC-Pan-092022	Papio anubis	80.76	5.00e-149	520.00
IUUC-Psi-093302	Pelodiscus sinensis	48.61	6.00e-94	337.00
IUUC-Pno-095083	Phaeosphaeria nodorum	25.19	3.00e-03	38.10
IUUC-Pfo-097250	Poecilia formosa	38.25	5.00e-48	185.00
IUUC-Pab-097929	Pongo abelii	81.31	6.00e-140	489.00
IUUC-Pca-100271	Procavia capensis	70.59	1.00e-43	169.00
IUUC-Pva-102234	Pteropus vampyrus	71.31	2.00e-120	425.00
IUUC-Rno-105850	Rattus norvegicus	74.61	4.00e-152	530.00
IUUC-Sha-107375	Sarcophilus harrisii	54.36	3.00e-101	362.00
IUUC-Ssc-116269	Sus scrofa	82.62	6.00e-163	566.00
IUUC-Tgu-116960	Taeniopygia guttata	52.44	9.00e-95	340.00
IUUC-Tru-118002	Takifugu rubripes	36.89	8.00e-48	184.00
IUUC-Tni-120023	Tetraodon nigroviridis	37.97	5.00e-49	188.00
IUUC-Tbe-127592	Tupaia belangeri	72.66	1.00e-137	482.00
IUUC-Ttr-128362	Tursiops truncatus	74.70	2.00e-123	435.00
IUUC-Vpa-130399	Vicugna pacos	78.87	4.00e-134	470.00
IUUC-Xtr-132677	Xenopus tropicalis	44.15	3.00e-76	279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence