iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093478

Ensembl Protein ID

ENSPSIP00000017220.1

UniProt Accession

K7GAA9; K7GAA9_PELSI

Genbank Protein ID

ENSPSIP00000017220

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01039465

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000015230.1	ENSPSIT00000017298.1	ENSPSIP00000017220.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.10e-21	74.2	45	111
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.40e-11	42.7	144	175

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v + +e +ah++vLaa+S++F a+f++++ esk  +++eikdv+ + ++ l++++Yt +++ +
   Q: 45   CDVVIVAEAVEMEAHRVVLAACSPYFCAMFTGDMTESK-AKKIEIKDVDGQTLSKLIDYIYTAEIEVT 111
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nclgi++fAd ++c++L ++a+ ++++hF+
   Q: 144  PTNCLGIRAFADVHTCTELLQQANAYAEQHFP 175
           78*****************************6 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

TKQRSQSPDE VEAKEKDERT VTVNPSHMGK AFKVMNELRS KRLLCDVVIV AEAVEMEAHR 60
VVLAACSPYF CAMFTGDMTE SKAKKIEIKD VDGQTLSKLI DYIYTAEIEV TEENVQVLLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGAAGACAT GCTGTGGTGG TTGATCTTCA GGCATTTGAT TTAGCGGGTC TAATAAAGAC 60
CTGCTAAATT AAAAGCTGAG CATGCTCCTG TTAATGCTGG TACTCCTGCA CTTCGCAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	91.32	0.00e+00	1071.00
IUUC-Apl-003965	Anas platyrhynchos	92.53	0.00e+00	1056.00
IUUC-Aca-004912	Anolis carolinensis	92.43	0.00e+00	1043.00
IUUC-Ame-010670	Astyanax mexicanus	76.83	0.00e+00	891.00
IUUC-Bta-013354	Bos taurus	91.67	0.00e+00	1072.00
IUUC-Bol-016582	Brassica oleracea	29.55	3.00e-13	70.50
IUUC-Bra-017771	Brassica rapa	30.28	1.00e-13	71.60
IUUC-Cel-018136	Caenorhabditis elegans	41.86	1.00e-126	446.00
IUUC-Cja-019183	Callithrix jacchus	88.15	0.00e+00	948.00
IUUC-Cfa-020465	Canis familiaris	91.16	0.00e+00	1068.00
IUUC-Cpo-022115	Cavia porcellus	91.46	0.00e+00	1075.00
IUUC-Csa-024219	Chlorocebus sabaeus	91.81	0.00e+00	1077.00
IUUC-Csv-026032	Ciona savignyi	58.25	0.00e+00	665.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	28.90	3.00e-21	95.50
IUUC-Dre-028524	Danio rerio	73.18	0.00e+00	902.00
IUUC-Dno-029075	Dasypus novemcinctus	93.51	0.00e+00	1064.00
IUUC-Dor-030156	Dipodomys ordii	75.78	0.00e+00	863.00
IUUC-Ete-033064	Echinops telfairi	76.47	0.00e+00	778.00
IUUC-Eca-033887	Equus caballus	93.23	0.00e+00	1071.00
IUUC-Eeu-035244	Erinaceus europaeus	72.13	0.00e+00	828.00
IUUC-Fca-035375	Felis catus	90.97	0.00e+00	1065.00
IUUC-Fal-037119	Ficedula albicollis	93.45	0.00e+00	1018.00
IUUC-Fso-038219	Fusarium solani	38.71	2.00e-09	53.10
IUUC-Gga-041094	Gallus gallus	93.94	0.00e+00	1051.00
IUUC-Gac-042585	Gasterosteus aculeatus	74.00	0.00e+00	865.00
IUUC-Ggo-045485	Gorilla gorilla	91.33	0.00e+00	1067.00
IUUC-Hsa-046717	Homo sapiens	91.67	0.00e+00	1076.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	91.81	0.00e+00	1073.00
IUUC-Lch-050246	Latimeria chalumnae	86.12	0.00e+00	967.00
IUUC-Laf-053700	Loxodonta africana	92.43	0.00e+00	1068.00
IUUC-Mcc-054732	Macaca mulatta	94.00	0.00e+00	955.00
IUUC-Mga-059994	Meleagris gallopavo	92.42	0.00e+00	956.00
IUUC-Mdo-062923	Monodelphis domestica	92.33	0.00e+00	1081.00
IUUC-Mmu-063842	Mus musculus	91.49	0.00e+00	1070.00
IUUC-Mpu-066380	Mustela putorius furo	91.29	0.00e+00	1073.00
IUUC-Mlu-067922	Myotis lucifugus	91.67	0.00e+00	1073.00
IUUC-Nle-069761	Nomascus leucogenys	91.49	0.00e+00	1075.00
IUUC-Opr-070287	Ochotona princeps	83.97	0.00e+00	960.00
IUUC-Ont-071654	Oreochromis niloticus	76.31	0.00e+00	907.00
IUUC-Ocu-074957	Oryctolagus cuniculus	91.32	0.00e+00	1063.00
IUUC-Ola-086853	Oryzias latipes	76.98	0.00e+00	859.00
IUUC-Oga-088559	Otolemur garnettii	90.81	0.00e+00	1066.00
IUUC-Oar-089925	Ovis aries	91.84	0.00e+00	1073.00
IUUC-Ptr-091487	Pan troglodytes	91.67	0.00e+00	1076.00
IUUC-Pan-091705	Papio anubis	91.81	0.00e+00	1077.00
IUUC-Pfo-097450	Poecilia formosa	78.52	0.00e+00	850.00
IUUC-Pab-097618	Pongo abelii	91.49	0.00e+00	1074.00
IUUC-Sha-106935	Sarcophilus harrisii	92.93	0.00e+00	691.00
IUUC-Ssc-115599	Sus scrofa	92.16	0.00e+00	1080.00
IUUC-Tgu-117001	Taeniopygia guttata	93.29	0.00e+00	1051.00
IUUC-Tru-118078	Takifugu rubripes	76.33	0.00e+00	902.00
IUUC-Tsy-119161	Tarsius syrichta	78.94	0.00e+00	818.00
IUUC-Tni-120888	Tetraodon nigroviridis	73.33	0.00e+00	839.00
IUUC-Tbe-127285	Tupaia belangeri	80.87	0.00e+00	650.00
IUUC-Ttr-128884	Tursiops truncatus	78.44	7.00e-145	507.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence