iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115314

Ensembl Protein ID

ENSSSCP00000010375.2

UniProt Accession

F1RIX9; F1RIX9_PIG

Genbank Protein ID

ENSSSCP00000010375

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU062559

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000009716.2	ENSSSCT00000010652.2	ENSSSCP00000010375.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.60e-08	33.2	12	53
UBD/SH3	6.00e-44	148.1	440	492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
             + y+y++ + deL+l+kG++ lv  + +   gW++g++  + + G+fP n+v+
   Q: 440  YVAVYPYTPRKRDELELRKGEMFLVF-ERC-QDGWVQGTSMHTSRIGVFPGNYVA 492
           6789*********************9.555.569*******************96 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
EQLPSNILLV RLLDGIKQRP WKPGPAGGSG TSCPNAARAQ GSAGANCSSK DIQGSQGAQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGAGT CCGCTCTGCT GGATCTTCTG GAGTGTCCCG TGTGTCTGGA GCGGCTCGAT 60
GCTTCCGCCA AGGTCTTGCC CTGCCAGCAC ACGTTTTGCA AACGCTGTTT GCTGGGCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	78.23	0.00e+00	1134.00
IUUC-Apl-003961	Anas platyrhynchos	72.86	0.00e+00	1041.00
IUUC-Aca-004386	Anolis carolinensis	69.67	0.00e+00	991.00
IUUC-Ame-010659	Astyanax mexicanus	64.94	0.00e+00	693.00
IUUC-Bta-012563	Bos taurus	72.90	9.00e-128	450.00
IUUC-Cja-019730	Callithrix jacchus	76.85	0.00e+00	1098.00
IUUC-Cfa-020992	Canis familiaris	79.64	0.00e+00	1146.00
IUUC-Cpo-021304	Cavia porcellus	78.00	0.00e+00	1167.00
IUUC-Csa-023925	Chlorocebus sabaeus	77.25	0.00e+00	1116.00
IUUC-Cho-024630	Choloepus hoffmanni	68.82	0.00e+00	704.00
IUUC-Cin-025274	Ciona intestinalis	46.79	2.00e-72	265.00
IUUC-Csv-026136	Ciona savignyi	42.22	3.00e-74	271.00
IUUC-Dre-028290	Danio rerio	67.65	0.00e+00	723.00
IUUC-Dno-029083	Dasypus novemcinctus	83.36	0.00e+00	941.00
IUUC-Dor-030388	Dipodomys ordii	90.73	0.00e+00	651.00
IUUC-Dme-032207	Drosophila melanogaster	45.56	6.00e-64	238.00
IUUC-Ete-032809	Echinops telfairi	69.95	0.00e+00	704.00
IUUC-Eca-034185	Equus caballus	77.68	0.00e+00	899.00
IUUC-Eeu-034816	Erinaceus europaeus	68.98	0.00e+00	933.00
IUUC-Fca-036439	Felis catus	77.91	0.00e+00	1155.00
IUUC-Fal-037074	Ficedula albicollis	71.84	0.00e+00	1009.00
IUUC-Gmo-039443	Gadus morhua	60.00	9.00e-117	414.00
IUUC-Ggr-040119	Gaeumannomyces graminis	42.37	9.00e-12	66.20
IUUC-Gga-040749	Gallus gallus	78.25	0.00e+00	860.00
IUUC-Gac-041420	Gasterosteus aculeatus	73.50	2.00e-150	526.00
IUUC-Ggo-045215	Gorilla gorilla	78.00	0.00e+00	1131.00
IUUC-Hsa-046315	Homo sapiens	77.94	0.00e+00	1128.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	68.58	1.00e-100	359.00
IUUC-Lch-049453	Latimeria chalumnae	64.99	0.00e+00	799.00
IUUC-Loc-052248	Lepisosteus oculatus	39.08	2.00e-72	266.00
IUUC-Laf-053651	Loxodonta africana	78.53	0.00e+00	1107.00
IUUC-Mcc-054688	Macaca mulatta	77.75	0.00e+00	1132.00
IUUC-Meu-056291	Macropus eugenii	64.79	4.00e-175	608.00
IUUC-Mor-056932	Magnaporthe oryzae	40.32	5.00e-12	67.00
IUUC-Mga-059944	Meleagris gallopavo	70.89	0.00e+00	1013.00
IUUC-Mmr-061553	Microcebus murinus	77.63	0.00e+00	1100.00
IUUC-Mdo-062313	Monodelphis domestica	69.74	0.00e+00	988.00
IUUC-Mmu-063516	Mus musculus	77.44	0.00e+00	1139.00
IUUC-Mpu-066064	Mustela putorius furo	79.25	0.00e+00	1130.00
IUUC-Mlu-067312	Myotis lucifugus	76.66	0.00e+00	1103.00
IUUC-Nle-069035	Nomascus leucogenys	78.02	0.00e+00	1133.00
IUUC-Opr-070690	Ochotona princeps	69.82	3.00e-131	462.00
IUUC-Ont-071484	Oreochromis niloticus	65.35	0.00e+00	713.00
IUUC-Oan-073305	Ornithorhynchus anatinus	79.21	0.00e+00	890.00
IUUC-Ocu-074936	Oryctolagus cuniculus	77.68	0.00e+00	1156.00
IUUC-Ola-086675	Oryzias latipes	61.84	9.00e-177	613.00
IUUC-Oga-087933	Otolemur garnettii	72.88	0.00e+00	850.00
IUUC-Oar-090408	Ovis aries	80.38	2.00e-173	602.00
IUUC-Ptr-090865	Pan troglodytes	78.16	0.00e+00	1133.00
IUUC-Pan-092362	Papio anubis	77.25	0.00e+00	1116.00
IUUC-Psi-093876	Pelodiscus sinensis	71.36	0.00e+00	1018.00
IUUC-Pfo-097116	Poecilia formosa	67.42	0.00e+00	719.00
IUUC-Pab-098127	Pongo abelii	77.91	0.00e+00	1131.00
IUUC-Pca-100485	Procavia capensis	82.42	0.00e+00	932.00
IUUC-Pva-102661	Pteropus vampyrus	77.56	0.00e+00	1097.00
IUUC-Rno-105728	Rattus norvegicus	76.64	0.00e+00	1105.00
IUUC-Sha-106515	Sarcophilus harrisii	78.10	0.00e+00	808.00
IUUC-Sar-113161	Sorex araneus	71.17	0.00e+00	974.00
IUUC-Tgu-117012	Taeniopygia guttata	73.32	0.00e+00	886.00
IUUC-Tru-118467	Takifugu rubripes	64.37	4.00e-158	552.00
IUUC-Tsy-119566	Tarsius syrichta	84.82	3.00e-169	588.00
IUUC-Tni-120830	Tetraodon nigroviridis	56.96	5.00e-165	574.00
IUUC-Tbe-128070	Tupaia belangeri	91.33	0.00e+00	681.00
IUUC-Ttr-128161	Tursiops truncatus	94.90	1.00e-141	496.00
IUUC-Xtr-132628	Xenopus tropicalis	73.03	0.00e+00	835.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence