iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119953

UUCD1 version

UUC-TeN-00451

Ensembl Protein ID

ENSTNIP00000001884.1

UniProt Accession

H3C0W8; H3C0W8_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000016052.1	ENSTNIT00000019369.1	ENSTNIP00000019141.1
ENSTNIG00000016052.1	ENSTNIT00000003388.1	ENSTNIP00000001884.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-57	188.2	142	178
UBD/Beta-Prp	3.00e-68	230.4	59	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +Ht++v+c +f +d +l++s++dD ti++WD+++ ++
   Q: 142  QHTNWVRCARFsPDeRLIASCGDDRTIRLWDTSSKHC 178
           5***********999****************988776 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           h++ it v+fsp+++l+at+s+d+t+++w+ + +   + ++ h+a+v++v fs +g  lvt+s+D+ +kvw++s ++ ++++++h++ v
   Q: 59   HQDAITGVQFSPSGNLVATSSKDRTVRLWKPSIKGESKVIKAHTAAVRSVAFSYEGHKLVTASDDKSVKVWSVSRRCFLYSFNQHTNWV 147
           7889*****************************9999999************************************************* PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           ++ +fsp+   ++s ++drtir+wd++++ c++ +l+   g+ ++v+++ +g +++s++ D+ +++Wdl+t++l+++ +  h+  v+s 
   Q: 148  RCARFSPDERLIASCGDDRTIRLWDTSSKHCIN-CLTDYGGSATSVNFDFSGTCIASSGSDGSLKIWDLRTNRLIQHYQV-HKAEVNSF 234
           *********************************.*********************************************8.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlqlhnssvi 268
           s++ + +++++gs d+tvk+ dl +g+ ++tl+gh+ +v  v+fs+++++++sg++Dg+  +W  + +++  l++lq+h  +++
   Q: 235  SYHLSNNFMITGSSDSTVKILDLLEGRLIYTLHGHKGPVFTVAFSRDGDLFASGGADGQMLMWrtNFDTKPDLSVLQQHSRRSS 318
           *****************************************************************999**99*****9986655 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MASVLEDPTL ERHFTGHKKA VTCADFSPNH TQLASGSVDK TLMIWNLASK ARSFCFIGHQ 60
DAITGVQFSP SGNLVATSSK DRTVRLWKPS IKGESKVIKA HTAAVRSVAF SYEGHKLVTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTCGG TTTTGGTAAG TAGACTTATC TACTGAGTAG CTTCTGAGTC GCTACCGAGG 60
AAAGGTGTGT TTTTCCGTAT ACCGACACTT GGAGCAAACA AGGCGACTTT GCTAGCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0060271--P:cilium assembly
GO:0060287--P:epithelial cilium movement involved in determination of left/right asymmetry
GO:0007507--P:heart development
GO:0007634--P:optokinetic behavior
GO:0003014--P:renal system process
GO:0010842--P:retina layer formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002219	Ailuropoda melanoleuca	48.10	4.00e-121	427.00
IUUC-Apl-004219	Anas platyrhynchos	50.45	5.00e-127	447.00
IUUC-Ame-011000	Astyanax mexicanus	57.79	1.00e-170	592.00
IUUC-Bta-012706	Bos taurus	48.47	2.00e-133	468.00
IUUC-Cfa-021274	Canis familiaris	48.31	7.00e-131	460.00
IUUC-Dre-028703	Danio rerio	63.03	1.00e-178	619.00
IUUC-Dme-032182	Drosophila melanogaster	45.87	2.00e-81	295.00
IUUC-Eeu-034611	Erinaceus europaeus	45.50	5.00e-96	344.00
IUUC-Gga-040847	Gallus gallus	50.52	2.00e-133	468.00
IUUC-Gac-041486	Gasterosteus aculeatus	50.20	1.00e-128	452.00
IUUC-Itr-048943	Ictidomys tridecemlineatus	49.44	1.00e-122	432.00
IUUC-Lch-050067	Latimeria chalumnae	55.65	1.00e-154	539.00
IUUC-Loc-052409	Lepisosteus oculatus	59.13	6.00e-165	573.00
IUUC-Mcc-054772	Macaca mulatta	48.16	3.00e-133	468.00
IUUC-Meu-056496	Macropus eugenii	48.21	1.00e-97	349.00
IUUC-Mga-059276	Meleagris gallopavo	48.63	7.00e-133	467.00
IUUC-Mmr-061525	Microcebus murinus	48.64	8.00e-133	466.00
IUUC-Mmu-063834	Mus musculus	48.55	2.00e-129	455.00
IUUC-Mpu-066453	Mustela putorius furo	48.78	1.00e-133	469.00
IUUC-Mlu-067909	Myotis lucifugus	48.46	1.00e-120	426.00
IUUC-Ont-072587	Oreochromis niloticus	74.32	2.00e-170	591.00
IUUC-Oan-073726	Ornithorhynchus anatinus	49.89	4.00e-123	434.00
IUUC-Ocu-074639	Oryctolagus cuniculus	48.79	1.00e-133	469.00
IUUC-Ola-086913	Oryzias latipes	62.82	2.00e-172	598.00
IUUC-Oga-088061	Otolemur garnettii	57.68	7.00e-122	429.00
IUUC-Oar-090228	Ovis aries	47.32	2.00e-132	465.00
IUUC-Pan-092228	Papio anubis	48.57	8.00e-133	466.00
IUUC-Psi-093309	Pelodiscus sinensis	51.26	2.00e-131	462.00
IUUC-Pfo-096162	Poecilia formosa	67.11	8.00e-148	516.00
IUUC-Pva-102712	Pteropus vampyrus	50.00	2.00e-134	472.00
IUUC-Rno-105260	Rattus norvegicus	48.46	1.00e-129	456.00
IUUC-Ssc-115794	Sus scrofa	55.92	8.00e-122	429.00
IUUC-Tgu-116770	Taeniopygia guttata	47.31	5.00e-121	427.00
IUUC-Tru-117968	Takifugu rubripes	75.21	0.00e+00	705.00
IUUC-Ttr-129267	Tursiops truncatus	49.08	1.00e-133	469.00
IUUC-Vpa-130823	Vicugna pacos	50.29	3.00e-99	355.00
IUUC-Xtr-131768	Xenopus tropicalis	51.88	4.00e-144	504.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence