iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bgr-011981

Ensembl Protein ID

CCU77239

UniProt Accession

N1JCF5; N1JCF5_BLUG1

Genbank Protein ID

CCU77239.1

Protein Name

E3 ubiquitin-protein ligase HECTD2

Genbank Nucleotide ID

CAUH01003460

Gene Name

BGHDH14_bgh03193

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BGHDH14_bgh03193	CCU77239	CCU77239

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.20e-77	257.1	863	1206

Active Site

Position(s)	Description	Evidence
1175	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           ++kk+l+++f+gEeg+d+gG+ +e++ ll+++++np+ g+f+y+e+ +++ + np+s+    e  + F ++G++lg+a++++ +ld+ l+++ +++ll 
   Q: 863  EIKKSLRITFKGEEGIDAGGLRKEWFLLLVRDVFNPEHGMFTYDED-SRMCYFNPHSF----ETSDQFFLVGVILGLAIYNSTILDVALPQFAFRKLLA 956
           6899*************************************99885.566688**999....6889999****************************98 PP
   S: 103  k................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkeg 185
                             +sl+dl++  p l++ l +++e+ + d+e + +   f ++ + +g++  + L+p+Gen  Vtn+N++e+v+l+v y l + 
   Q: 957  AspppapgaathtkpsmTYSLDDLAQYRPALANGLRQLLEY-DGDVEST-FLRDFVAEFDRYGQVVRVPLCPDGENRTVTNANRREFVELYVRYLLDTA 1053
           877766666666666556999********************.6788887.8899999****************************************** PP
   S: 186  ikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky...kggyte.dspaiqwFwevleefsseerkafLqFvTgssrlPlgGf 279
           +++q+e f++Gf +v+  + lslF++ee+elli G+ e +d+ +l++ ++      ++++ d+p+++wFwe++e+ + ++++++L FvTgs+r+P+ G 
   Q: 1054 VTRQFEPFKRGFFTVCGGNALSLFRPEEIELLIRGSdEPLDITSLRAVCECenwGTHINPgDEPVLDWFWETFESSKPNDQRKLLSFVTGSDRIPAMGA 1152
           ************************************999*********955444445554278899********************************* PP
   S: 280  aelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            +l  +l +  +  +++r+P + TCfn+L LP+Yssk+ l+++L  A+ e++gF+l
   Q: 1153 TNLIIKLSCAGD--DENRFPVARTCFNQLSLPRYSSKQRLESMLWRAVVESEGFGL 1206
           ****88777766..77**************************************98 PP

Organism

Blumeria graminis

Protein Sequence
(Fasta)

MPQWSSRLLS SSPRFEQAGQ KVVIGNSTPN SQIQQAAIES RPAESLAIPG LPNANTNNNI 60
SVSSLTSASS SHVRSISNPF PSFFSGKKKR FVETTTNVGA TGIESTDQDT EPPTTNRNSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTCAAT GGTCCAGCCG TTTATTGTCA TCCAGCCCAC GCTTTGAGCA GGCTGGTCAA 60
AAGGTCGTCA TTGGGAACTC CACGCCTAAT TCTCAAATAC AACAGGCGGC TATTGAGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	32.24	6.00e-95	339.00
IUUC-Atr-003144	Amborella trichopoda	39.44	8.00e-81	292.00
IUUC-Apl-003589	Anas platyrhynchos	40.22	2.00e-88	318.00
IUUC-Aca-004350	Anolis carolinensis	39.78	3.00e-91	327.00
IUUC-Ago-007908	Ashbya gossypii	31.23	9.00e-94	336.00
IUUC-Acl-008288	Aspergillus clavatus	53.54	0.00e+00	903.00
IUUC-Afl-008402	Aspergillus flavus	56.52	0.00e+00	764.00
IUUC-Afu-008762	Aspergillus fumigatus	47.38	0.00e+00	1013.00
IUUC-Ani-009176	Aspergillus nidulans	59.52	0.00e+00	743.00
IUUC-Ang-009791	Aspergillus niger	47.52	0.00e+00	912.00
IUUC-Aor-009921	Aspergillus oryzae	62.05	0.00e+00	739.00
IUUC-Ate-010295	Aspergillus terreus	47.24	0.00e+00	949.00
IUUC-Ame-011166	Astyanax mexicanus	39.10	3.00e-82	297.00
IUUC-Bta-012945	Bos taurus	40.39	5.00e-94	337.00
IUUC-Bci-013697	Botrytis cinerea	54.95	0.00e+00	1095.00
IUUC-Cel-018150	Caenorhabditis elegans	29.85	2.00e-49	189.00
IUUC-Cja-019263	Callithrix jacchus	39.74	9.00e-93	332.00
IUUC-Cfa-020486	Canis familiaris	32.29	2.00e-95	341.00
IUUC-Cpo-021755	Cavia porcellus	32.14	8.00e-95	339.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	39.41	1.00e-57	214.00
IUUC-Csa-023378	Chlorocebus sabaeus	39.34	1.00e-79	289.00
IUUC-Cho-025059	Choloepus hoffmanni	32.23	4.00e-72	264.00
IUUC-Cin-025643	Ciona intestinalis	28.75	2.00e-65	242.00
IUUC-Csv-026282	Ciona savignyi	35.33	4.00e-59	221.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	47.68	0.00e+00	964.00
IUUC-Cme-027151	Cyanidioschyzon merolae	36.05	8.00e-77	280.00
IUUC-Dre-028551	Danio rerio	39.69	3.00e-89	320.00
IUUC-Dno-029497	Dasypus novemcinctus	40.44	4.00e-94	337.00
IUUC-Dor-030158	Dipodomys ordii	33.47	5.00e-71	260.00
IUUC-Dse-031239	Dothistroma septosporum	49.57	0.00e+00	877.00
IUUC-Dme-032103	Drosophila melanogaster	34.07	1.00e-68	253.00
IUUC-Ete-032902	Echinops telfairi	31.91	5.00e-84	303.00
IUUC-Eca-033678	Equus caballus	32.14	2.00e-95	341.00
IUUC-Eeu-035109	Erinaceus europaeus	32.61	8.00e-72	263.00
IUUC-Fca-035590	Felis catus	32.57	5.00e-97	346.00
IUUC-Fal-036747	Ficedula albicollis	39.81	3.00e-80	291.00
IUUC-Fox-037941	Fusarium oxysporum	48.13	0.00e+00	1013.00
IUUC-Fso-038388	Fusarium solani	48.74	0.00e+00	1032.00
IUUC-Gmo-039553	Gadus morhua	40.18	8.00e-79	286.00
IUUC-Ggr-040110	Gaeumannomyces graminis	46.39	0.00e+00	944.00
IUUC-Gga-040406	Gallus gallus	39.78	7.00e-91	326.00
IUUC-Gac-042141	Gasterosteus aculeatus	39.12	2.00e-86	311.00
IUUC-Ggo-045504	Gorilla gorilla	39.30	3.00e-92	330.00
IUUC-Hsa-045786	Homo sapiens	39.30	3.00e-92	331.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	38.86	2.00e-77	281.00
IUUC-Kpa-049152	Komagataella pastoris	30.49	6.00e-82	296.00
IUUC-Lch-050197	Latimeria chalumnae	39.57	2.00e-83	302.00
IUUC-Loc-052173	Lepisosteus oculatus	31.14	2.00e-93	335.00
IUUC-Laf-054017	Loxodonta africana	40.39	6.00e-94	336.00
IUUC-Mcc-055713	Macaca mulatta	39.74	1.00e-92	332.00
IUUC-Meu-056061	Macropus eugenii	33.28	4.00e-79	287.00
IUUC-Mor-057045	Magnaporthe oryzae	46.15	0.00e+00	967.00
IUUC-Mla-059187	Melampsora laricipopulina	43.17	3.00e-96	343.00
IUUC-Mga-059884	Meleagris gallopavo	40.14	2.00e-86	311.00
IUUC-Mmr-061344	Microcebus murinus	30.81	7.00e-96	343.00
IUUC-Mdo-062653	Monodelphis domestica	40.39	8.00e-93	333.00
IUUC-Mmu-063775	Mus musculus	40.09	1.00e-93	335.00
IUUC-Mpu-066069	Mustela putorius furo	32.38	9.00e-96	342.00
IUUC-Mlu-067925	Myotis lucifugus	40.61	6.00e-95	339.00
IUUC-Nfi-068439	Neosartorya fischeri	53.89	0.00e+00	921.00
IUUC-Ncr-068903	Neurospora crassa	47.51	0.00e+00	932.00
IUUC-Nle-070046	Nomascus leucogenys	31.68	2.00e-93	335.00
IUUC-Opr-070570	Ochotona princeps	30.12	9.00e-61	226.00
IUUC-Ont-072126	Oreochromis niloticus	33.06	2.00e-88	318.00
IUUC-Oan-072933	Ornithorhynchus anatinus	39.87	9.00e-92	329.00
IUUC-Ocu-073800	Oryctolagus cuniculus	40.39	5.00e-94	336.00
IUUC-Ola-086988	Oryzias latipes	33.50	3.00e-87	314.00
IUUC-Oga-088117	Otolemur garnettii	40.17	2.00e-92	331.00
IUUC-Oar-089371	Ovis aries	40.39	8.00e-94	336.00
IUUC-Ptr-090551	Pan troglodytes	39.30	2.00e-92	331.00
IUUC-Pan-092067	Papio anubis	39.74	1.00e-92	332.00
IUUC-Psi-092963	Pelodiscus sinensis	39.12	1.00e-89	322.00
IUUC-Pma-094643	Petromyzon marinus	37.53	1.00e-80	292.00
IUUC-Ppa-095354	Physcomitrella patens	39.82	3.00e-91	328.00
IUUC-Pfo-096562	Poecilia formosa	31.66	7.00e-87	313.00
IUUC-Pab-098680	Pongo abelii	39.52	1.00e-92	332.00
IUUC-Pca-100869	Procavia capensis	33.44	4.00e-80	291.00
IUUC-Pva-103040	Pteropus vampyrus	41.33	5.00e-69	254.00
IUUC-Pgr-103315	Puccinia graminis	43.42	9.00e-104	369.00
IUUC-Ptt-103736	Puccinia triticina	43.04	1.00e-102	365.00
IUUC-Rno-105270	Rattus norvegicus	40.39	2.00e-94	338.00
IUUC-Sce-106306	Saccharomyces cerevisiae	33.28	1.00e-79	289.00
IUUC-Sha-106819	Sarcophilus harrisii	32.62	3.00e-96	344.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	37.80	3.00e-60	224.00
IUUC-Spo-108271	Schizosaccharomyces pombe	35.29	1.00e-106	379.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	54.01	0.00e+00	1124.00
IUUC-Smo-108858	Selaginella moellendorffii	40.97	1.00e-84	305.00
IUUC-Sar-113293	Sorex araneus	39.34	5.00e-79	287.00
IUUC-Ssc-115441	Sus scrofa	40.09	6.00e-93	333.00
IUUC-Tgu-117166	Taeniopygia guttata	37.62	1.00e-87	315.00
IUUC-Tru-118368	Takifugu rubripes	38.86	6.00e-82	296.00
IUUC-Tsy-118898	Tarsius syrichta	34.72	1.00e-69	256.00
IUUC-Tni-120143	Tetraodon nigroviridis	39.10	6.00e-82	296.00
IUUC-Tre-122108	Trichoderma reesei	48.38	0.00e+00	956.00
IUUC-Tvi-122644	Trichoderma virens	47.69	0.00e+00	955.00
IUUC-Tme-127004	Tuber melanosporum	50.62	0.00e+00	797.00
IUUC-Tbe-127640	Tupaia belangeri	36.83	4.00e-65	241.00
IUUC-Ttr-128352	Tursiops truncatus	37.77	1.00e-85	309.00
IUUC-Vda-129969	Verticillium dahliae	47.89	0.00e+00	987.00
IUUC-Vpa-130448	Vicugna pacos	34.11	3.00e-72	265.00
IUUC-Xtr-132881	Xenopus tropicalis	37.97	2.00e-84	305.00
IUUC-Xma-133122	Xiphophorus maculatus	38.39	1.00e-80	292.00
IUUC-Yli-134470	Yarrowia lipolytica	34.98	6.00e-101	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence