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Tag Content
UUCD2 ID IUUC-Aml-001836
UUCD1 version UUC-AiM-01095
Ensembl Protein ID ENSAMEP00000006366.1
UniProt Accession D2HZX6; D2HZX6_AILME
Genbank Protein ID EFB29174.1
Protein Name Putative uncharacterized protein
Genbank Nucleotide ID ACTA01170072
Gene Name USP28; PANDA_018399
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000006005.1 ENSAMET00000006627.1 ENSAMEP00000006366.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.00e-58 197.7 143 633
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L+++pe+r+l+l+     +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 143  VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSyslpqNVLENCPSH-TEKRNIVFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 229
           6******************************96555445555543.3678889******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            + +qqD++Ef++ lld le++++                     + +++ +k+++++++lF g++ ++ + +        +e+f +++
   Q: 230  PEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVNNPRNKSENPMVQLFYGTFLTEGVREGKPFC--NNETFGQYP 298
           799********************22..................23457899****************99998665555..5899***** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e  +e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 299  LQVNGYR-----NLDECLEGAMVEGDIE----LLPSD--HSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 376
           *******.....99****7766666665....55544..456778899***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++ +                                                                                    
   Q: 377  RYMYKskelirskrecirklkeeikvlqqkleryvkygsgparfplpdmlkyviefastkpasesstsqsnacvtlplssahcpvsdla 465
           **999888888888888888888888888888888888888888888888888888888877777666666666666666666666666 PP
   S: 268  ......peekqke............................................................................ 274
                 +     e                                                                            
   Q: 466  skestsK-----Esssqdvegtfsspedslpkskamnkplpssrssmempaqpaprtvtdeemnfvktclqrwrseieqdiqdlkncia 549
           6555540.....15555666777777777777777777888888888888888888888888889999999999999999999999999 PP
   S: 275  ................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                           ++ Y+L+av+vH+G+++ GHY+ayv+n+ ++ Wl+++D +Vte+++ee ++++       +aY+l+Y 
   Q: 550  sttqaieqmyrdpllrQVPYRLHAVLVHEGQANAGHYWAYVYNQPRQvWLKYNDISVTESSWEELERDSYgglrnVSAYCLMYI 633
           9999999************************************99999*******************8879************6 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
SCQMLLNQLR EITGIQDPSF LHEALKASNG DITQAVSLLT EERVKEPSQD TTATEPSEVE 60
GSAASKEVLA KVIDLTHDNK DDLQAAIALS LLESPKIQAD GRDLNRMHEA ASAENKRSKR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001836|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCTGCCAAA TGCTGTTAAA CCAACTAAGA GAAATCACAG GCATTCAGGA CCCTTCCTTT 60
CTTCATGAAG CTCTGAAGGT TAGTTTCAAG GCTGCTGTTA GTCAACAGGC TTTAAAACAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001836|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-004010 Anas platyrhynchos 69.74 0.00e+00 1475.00
IUUC-Aca-004741 Anolis carolinensis 58.84 0.00e+00 839.00
IUUC-Afu-008871 Aspergillus fumigatus 23.08 3.00e-12 67.80
IUUC-Ang-009577 Aspergillus niger 36.36 2.00e-11 65.50
IUUC-Ate-010275 Aspergillus terreus 35.19 2.00e-11 64.70
IUUC-Bta-013377 Bos taurus 93.79 0.00e+00 1941.00
IUUC-Cja-019977 Callithrix jacchus 94.17 0.00e+00 1978.00
IUUC-Cfa-020378 Canis familiaris 96.53 0.00e+00 1431.00
IUUC-Cpo-021817 Cavia porcellus 90.98 0.00e+00 1928.00
IUUC-Csa-023446 Chlorocebus sabaeus 92.72 0.00e+00 1364.00
IUUC-Cho-024717 Choloepus hoffmanni 84.33 0.00e+00 1233.00
IUUC-Cme-027167 Cyanidioschyzon merolae 32.49 7.00e-16 79.70
IUUC-Dre-028105 Danio rerio 57.08 0.00e+00 719.00
IUUC-Dno-029559 Dasypus novemcinctus 90.68 0.00e+00 1509.00
IUUC-Dor-030955 Dipodomys ordii 90.50 0.00e+00 1923.00
IUUC-Ete-032828 Echinops telfairi 82.51 0.00e+00 1172.00
IUUC-Eca-034300 Equus caballus 94.44 0.00e+00 1951.00
IUUC-Eeu-034458 Erinaceus europaeus 89.35 0.00e+00 1726.00
IUUC-Fca-035753 Felis catus 96.61 0.00e+00 2067.00
IUUC-Fal-037062 Ficedula albicollis 64.46 0.00e+00 886.00
IUUC-Gmo-039593 Gadus morhua 52.19 0.00e+00 1036.00
IUUC-Gga-040878 Gallus gallus 65.21 0.00e+00 1329.00
IUUC-Gac-041867 Gasterosteus aculeatus 54.55 0.00e+00 1118.00
IUUC-Ggo-045384 Gorilla gorilla 94.36 0.00e+00 1988.00
IUUC-Hsa-046277 Homo sapiens 94.54 0.00e+00 1995.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 86.57 0.00e+00 1150.00
IUUC-Lch-049692 Latimeria chalumnae 66.98 0.00e+00 1400.00
IUUC-Laf-053808 Loxodonta africana 86.95 0.00e+00 1814.00
IUUC-Mcc-055473 Macaca mulatta 92.72 0.00e+00 1365.00
IUUC-Meu-056416 Macropus eugenii 74.93 0.00e+00 1526.00
IUUC-Mga-060011 Meleagris gallopavo 67.44 0.00e+00 1412.00
IUUC-Mmr-060720 Microcebus murinus 91.34 0.00e+00 1887.00
IUUC-Mdo-061955 Monodelphis domestica 85.07 0.00e+00 1287.00
IUUC-Mmu-063870 Mus musculus 87.22 0.00e+00 1854.00
IUUC-Mpu-066454 Mustela putorius furo 96.13 0.00e+00 1387.00
IUUC-Mlu-067487 Myotis lucifugus 88.35 0.00e+00 1870.00
IUUC-Nle-070044 Nomascus leucogenys 94.36 0.00e+00 1989.00
IUUC-Opr-070888 Ochotona princeps 97.11 2.00e-160 560.00
IUUC-Ont-072386 Oreochromis niloticus 55.46 0.00e+00 741.00
IUUC-Ocu-074523 Oryctolagus cuniculus 91.35 0.00e+00 1925.00
IUUC-Ola-086393 Oryzias latipes 54.60 0.00e+00 1115.00
IUUC-Oga-088618 Otolemur garnettii 92.66 0.00e+00 1952.00
IUUC-Oar-089848 Ovis aries 84.86 0.00e+00 1830.00
IUUC-Ptr-091630 Pan troglodytes 93.97 0.00e+00 1519.00
IUUC-Psi-093422 Pelodiscus sinensis 65.04 0.00e+00 1395.00
IUUC-Pma-094250 Petromyzon marinus 51.89 1.00e-72 266.00
IUUC-Pfo-096466 Poecilia formosa 56.86 0.00e+00 755.00
IUUC-Pab-098337 Pongo abelii 94.54 0.00e+00 1990.00
IUUC-Pca-100901 Procavia capensis 77.80 0.00e+00 1576.00
IUUC-Pva-102226 Pteropus vampyrus 88.91 0.00e+00 1751.00
IUUC-Rno-105735 Rattus norvegicus 84.09 0.00e+00 1858.00
IUUC-Sha-107489 Sarcophilus harrisii 87.80 0.00e+00 1872.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 34.57 3.00e-09 58.20
IUUC-Ssc-115463 Sus scrofa 69.85 0.00e+00 1009.00
IUUC-Tgu-116609 Taeniopygia guttata 68.48 0.00e+00 1405.00
IUUC-Tru-117807 Takifugu rubripes 54.58 0.00e+00 1096.00
IUUC-Tsy-118971 Tarsius syrichta 87.52 0.00e+00 1234.00
IUUC-Tni-119983 Tetraodon nigroviridis 54.94 0.00e+00 1123.00
IUUC-Ttr-128887 Tursiops truncatus 88.52 0.00e+00 1821.00
IUUC-Vpa-130614 Vicugna pacos 93.53 0.00e+00 1519.00
IUUC-Xtr-132436 Xenopus tropicalis 62.85 0.00e+00 1288.00
Created Date 25-Jun-2017

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