iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117884

Ensembl Protein ID

ENSTRUP00000030785.1

UniProt Accession

H2U1H4; H2U1H4_TAKRU

Protein Name

Uncharacterized protein

Gene Name

vav3b; LOC101076765

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000012168.1	ENSTRUT00000030902.1	ENSTRUP00000030785.1
ENSTRUG00000012168.1	ENSTRUT00000030903.1	ENSTRUP00000030786.1
ENSTRUG00000012168.1	ENSTRUT00000030904.1	ENSTRUP00000030787.1
ENSTRUG00000012168.1	ENSTRUT00000030905.1	ENSTRUP00000030788.1
ENSTRUG00000012168.1	ENSTRUT00000030906.1	ENSTRUP00000030789.1
ENSTRUG00000012168.1	ENSTRUT00000030907.1	ENSTRUP00000030790.1
ENSTRUG00000012168.1	ENSTRUT00000030908.1	ENSTRUP00000030791.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.60e-16	59.0	798	850

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +  + yd+ + ++ eL+l kGd+++v   ++   gW+kg  e  g+ G fP+ +ve+
   Q: 798  VAVARYDFASRDTQELSLLKGDIIRVY--TKLPDGWWKG--EVDGRVGWFPSTYVEE 850
           56789*********************8..99999*****..9************985 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MEYWRQCAMW LISCNVLPKN HRVVADRAQV FDLAQTLRDG VLLCQLLNNL RPHTINLKEI 60
NLRPQMSQFL CLKNIRTFLT SCNVAFAMKK IDLFDAFDLF DVRDFGKVMD TLSRLSHTVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGTACT GGAGGCAGTG CGCGATGTGG CTGATCAGCT GCAACGTGCT GCCGAAGAAC 60
CACCGCGTCG TGGCGGACAG GGCGCAGGTG TTCGACCTGG CGCAGACCCT GCGGGACGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00621--RhoGEF
PF00017--SH2
PF07653--SH3_2

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	66.67	0.00e+00	1108.00
IUUC-Ago-007868	Ashbya gossypii	44.07	9.00e-08	51.60
IUUC-Ame-011279	Astyanax mexicanus	63.00	0.00e+00	1040.00
IUUC-Bta-012722	Bos taurus	66.04	0.00e+00	1100.00
IUUC-Cja-018941	Callithrix jacchus	66.15	0.00e+00	1098.00
IUUC-Cin-025115	Ciona intestinalis	36.43	2.00e-140	493.00
IUUC-Csv-025995	Ciona savignyi	35.21	3.00e-140	492.00
IUUC-Dre-028199	Danio rerio	67.39	0.00e+00	1157.00
IUUC-Dno-029474	Dasypus novemcinctus	65.69	0.00e+00	1106.00
IUUC-Fca-036572	Felis catus	66.11	0.00e+00	1075.00
IUUC-Gmo-038569	Gadus morhua	71.92	0.00e+00	1244.00
IUUC-Gga-040884	Gallus gallus	65.26	0.00e+00	1119.00
IUUC-Gac-042533	Gasterosteus aculeatus	80.21	0.00e+00	1424.00
IUUC-Hsa-046099	Homo sapiens	64.06	0.00e+00	1098.00
IUUC-Laf-054564	Loxodonta africana	65.93	0.00e+00	1113.00
IUUC-Mcc-054622	Macaca mulatta	63.83	0.00e+00	1096.00
IUUC-Meu-056680	Macropus eugenii	60.07	0.00e+00	1012.00
IUUC-Mga-060013	Meleagris gallopavo	64.67	0.00e+00	1085.00
IUUC-Mmr-061251	Microcebus murinus	62.67	0.00e+00	1112.00
IUUC-Mdo-061875	Monodelphis domestica	65.34	0.00e+00	1109.00
IUUC-Mmu-063735	Mus musculus	66.39	0.00e+00	1154.00
IUUC-Mpu-065856	Mustela putorius furo	66.16	0.00e+00	1116.00
IUUC-Mlu-068108	Myotis lucifugus	63.38	0.00e+00	1061.00
IUUC-Opr-070372	Ochotona princeps	56.66	0.00e+00	699.00
IUUC-Ont-072249	Oreochromis niloticus	77.94	0.00e+00	1415.00
IUUC-Ocu-074194	Oryctolagus cuniculus	65.81	0.00e+00	1117.00
IUUC-Oar-089272	Ovis aries	66.04	0.00e+00	1131.00
IUUC-Ptr-090652	Pan troglodytes	64.25	0.00e+00	1096.00
IUUC-Pfo-096153	Poecilia formosa	81.10	0.00e+00	1415.00
IUUC-Pab-098698	Pongo abelii	64.05	0.00e+00	1095.00
IUUC-Pva-102262	Pteropus vampyrus	65.20	0.00e+00	1059.00
IUUC-Rno-105421	Rattus norvegicus	67.21	0.00e+00	1154.00
IUUC-Sha-107325	Sarcophilus harrisii	65.22	0.00e+00	1117.00
IUUC-Sar-113456	Sorex araneus	62.54	0.00e+00	1051.00
IUUC-Tgu-116595	Taeniopygia guttata	64.31	0.00e+00	1062.00
IUUC-Tni-120835	Tetraodon nigroviridis	84.83	0.00e+00	1476.00
IUUC-Tbe-127995	Tupaia belangeri	63.34	4.00e-131	462.00
IUUC-Ttr-128281	Tursiops truncatus	66.04	0.00e+00	1100.00
IUUC-Xtr-132427	Xenopus tropicalis	59.02	0.00e+00	1028.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence