iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013454

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

E3 ubiquitin-protein ligase RNF128

Genbank Nucleotide ID

DAAA02071287

Gene Name

RNF128

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000022920.4	ENSBTAT00000031148.4	ENSBTAP00000031108.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-06	27.4	280	321

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e +   d +++l C+Hvfh++C+  w         + +CP C+
   Q: 280  CAVCIELYkpNDLVRILTCNHVFHKTCVDPW------LLEHRTCPMCK 321
           *****9985545499****************......9999******6 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MGQLPGAGVF CRGGCGFSRL LAWCFLLVLS PQTPGSRGAE AVWTAYLNVS WRVPHTGVNR 60
TVWELSEEGV YGQDSPLEPV AGVLVPPDGP GALNACNPHT NFTVPTVPGD WGSSVQVSWL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCGCGGAG AGGAGTGGAG CCACAAAGGG CTTCCTCTGC GGCAACATCT CCGGCGACGC 60
TACGTGCCCG CCGGCTCTGA CCCAGCCCGC CGCGCGCGCC AGTCTCGTCC CGTCCTCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0005770--C:late endosome
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042036--P:negative regulation of cytokine biosynthetic process
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000714	Aegilops tauschii	39.18	5.00e-13	67.40
IUUC-Aml-001674	Ailuropoda melanoleuca	96.29	0.00e+00	838.00
IUUC-Apl-003776	Anas platyrhynchos	66.56	2.00e-107	381.00
IUUC-Aca-004318	Anolis carolinensis	69.05	2.00e-119	422.00
IUUC-Ani-009454	Aspergillus nidulans	54.17	2.00e-10	60.10
IUUC-Ame-011286	Astyanax mexicanus	45.00	3.00e-84	305.00
IUUC-Bci-013726	Botrytis cinerea	54.00	9.00e-13	68.20
IUUC-Cja-019864	Callithrix jacchus	95.13	0.00e+00	818.00
IUUC-Cfa-020185	Canis familiaris	95.13	0.00e+00	826.00
IUUC-Cpo-022417	Cavia porcellus	52.96	3.00e-86	311.00
IUUC-Csa-023224	Chlorocebus sabaeus	94.20	0.00e+00	785.00
IUUC-Cho-024710	Choloepus hoffmanni	80.12	9.00e-150	522.00
IUUC-Cne-026951	Cryptococcus neoformans	34.69	8.00e-11	61.60
IUUC-Dre-028249	Danio rerio	52.34	2.00e-88	319.00
IUUC-Dno-029216	Dasypus novemcinctus	95.20	4.00e-137	480.00
IUUC-Dor-030487	Dipodomys ordii	81.64	0.00e+00	656.00
IUUC-Dse-031357	Dothistroma septosporum	45.21	1.00e-12	67.80
IUUC-Ete-032376	Echinops telfairi	94.95	8.00e-137	479.00
IUUC-Eca-034264	Equus caballus	96.06	0.00e+00	837.00
IUUC-Eeu-034606	Erinaceus europaeus	92.55	3.00e-131	461.00
IUUC-Fca-036503	Felis catus	95.82	0.00e+00	833.00
IUUC-Fal-036671	Ficedula albicollis	59.84	4.00e-111	394.00
IUUC-Gmo-039483	Gadus morhua	49.02	1.00e-79	289.00
IUUC-Gga-040248	Gallus gallus	61.99	3.00e-133	468.00
IUUC-Ggo-045319	Gorilla gorilla	53.77	6.00e-92	330.00
IUUC-Hsa-046745	Homo sapiens	94.20	0.00e+00	814.00
IUUC-Itr-048362	Ictidomys tridecemlineatus	94.66	0.00e+00	818.00
IUUC-Kpa-049143	Komagataella pastoris	50.98	3.00e-11	63.50
IUUC-Lch-050549	Latimeria chalumnae	57.46	8.00e-122	430.00
IUUC-Loc-051929	Lepisosteus oculatus	55.81	7.00e-96	343.00
IUUC-Laf-054197	Loxodonta africana	93.97	0.00e+00	789.00
IUUC-Mcc-055146	Macaca mulatta	94.66	0.00e+00	790.00
IUUC-Meu-056649	Macropus eugenii	75.18	5.00e-163	566.00
IUUC-Mga-059520	Meleagris gallopavo	62.11	6.00e-134	470.00
IUUC-Mmr-061502	Microcebus murinus	93.97	0.00e+00	783.00
IUUC-Mdo-062875	Monodelphis domestica	63.46	3.00e-124	438.00
IUUC-Mmu-064235	Mus musculus	93.97	0.00e+00	812.00
IUUC-Mpu-066452	Mustela putorius furo	92.42	1.00e-174	605.00
IUUC-Mlu-067189	Myotis lucifugus	94.66	0.00e+00	805.00
IUUC-Ncr-068771	Neurospora crassa	44.05	3.00e-14	73.20
IUUC-Nle-070026	Nomascus leucogenys	94.90	0.00e+00	793.00
IUUC-Opr-070435	Ochotona princeps	71.05	2.00e-95	341.00
IUUC-Oan-073238	Ornithorhynchus anatinus	75.86	1.00e-116	412.00
IUUC-Ocu-074960	Oryctolagus cuniculus	94.90	0.00e+00	778.00
IUUC-Ola-086348	Oryzias latipes	46.21	6.00e-77	280.00
IUUC-Oga-088543	Otolemur garnettii	92.58	0.00e+00	799.00
IUUC-Oar-089599	Ovis aries	99.07	0.00e+00	860.00
IUUC-Ptr-091576	Pan troglodytes	91.22	3.00e-167	580.00
IUUC-Pan-091690	Papio anubis	94.44	0.00e+00	786.00
IUUC-Psi-093642	Pelodiscus sinensis	77.44	7.00e-106	376.00
IUUC-Pfo-096270	Poecilia formosa	46.49	3.00e-77	281.00
IUUC-Pab-097965	Pongo abelii	94.20	0.00e+00	785.00
IUUC-Pva-102991	Pteropus vampyrus	84.75	4.00e-177	613.00
IUUC-Rno-105667	Rattus norvegicus	93.97	0.00e+00	813.00
IUUC-Sha-107293	Sarcophilus harrisii	76.86	1.00e-155	542.00
IUUC-Ssl-108451	Sclerotinia sclerotiorum	54.00	1.00e-12	67.80
IUUC-Sar-113682	Sorex araneus	93.61	1.00e-141	495.00
IUUC-Ssc-115583	Sus scrofa	96.06	0.00e+00	831.00
IUUC-Tgu-117406	Taeniopygia guttata	58.43	7.00e-82	296.00
IUUC-Tru-118147	Takifugu rubripes	43.86	1.00e-72	266.00
IUUC-Tsy-118918	Tarsius syrichta	92.58	0.00e+00	753.00
IUUC-Tni-120865	Tetraodon nigroviridis	45.40	1.00e-68	253.00
IUUC-Tbe-127498	Tupaia belangeri	53.23	1.00e-105	376.00
IUUC-Ttr-128640	Tursiops truncatus	96.29	0.00e+00	808.00
IUUC-Vpa-130536	Vicugna pacos	88.32	0.00e+00	732.00
IUUC-Xma-133114	Xiphophorus maculatus	47.99	7.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence