iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-044456

Ensembl Protein ID

ENSGGOP00000008780.2

UniProt Accession

G3R0T4; G3R0T4_GORGO

Protein Name

Uncharacterized protein

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000008982.2	ENSGGOT00000009019.2	ENSGGOP00000008780.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.90e-11	42.7	199	225

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
            +W+C+ CTf+N+P +++CemC+r R+
   Q: 199  VGWQCPGCTFINKPTRPGCEMCCRARP 225
           68************************8 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

PNEPSVRTEE MALSLTRAVA GGDEQVAMKC AIWLAEQRVP LSVQLKPEVS PTQDISLCST 60
FSLLDSKAIV LWFLIFGSLG GSHLVFLTFH AFGFPNMLED PQWLMSLEGG LEASKEVAPE 120

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Nucleotide Sequence
(Fasta)

CCAAATGAGC CTAGTGTGAG GAGGAGTGGG GAATATTAGA GAACCCCTCC CGGAGAAAGG 60
GACTTTTAGT CTGGGTGCTG AAGGATATGT AGGAGTTCAC CAGGAAGACA GAGAAAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF01485--IBR

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	62.69	7.00e-150	523.00
IUUC-Apl-003627	Anas platyrhynchos	60.81	8.00e-19	84.30
IUUC-Aca-004507	Anolis carolinensis	47.73	4.00e-98	351.00
IUUC-Ame-011008	Astyanax mexicanus	41.78	3.00e-95	342.00
IUUC-Bta-013247	Bos taurus	64.81	2.00e-164	572.00
IUUC-Cja-018880	Callithrix jacchus	67.69	1.00e-171	596.00
IUUC-Cfa-020477	Canis familiaris	64.42	3.00e-164	571.00
IUUC-Cpo-021558	Cavia porcellus	62.81	8.00e-158	550.00
IUUC-Csa-024129	Chlorocebus sabaeus	67.69	7.00e-159	553.00
IUUC-Cin-025630	Ciona intestinalis	36.36	1.00e-54	207.00
IUUC-Csv-026069	Ciona savignyi	46.64	4.00e-53	201.00
IUUC-Dre-027591	Danio rerio	41.57	2.00e-89	323.00
IUUC-Dno-029015	Dasypus novemcinctus	64.04	5.00e-162	563.00
IUUC-Dor-030313	Dipodomys ordii	55.86	7.00e-128	450.00
IUUC-Ete-032908	Echinops telfairi	52.84	3.00e-126	445.00
IUUC-Eca-034295	Equus caballus	49.42	1.00e-116	413.00
IUUC-Eeu-034454	Erinaceus europaeus	50.66	2.00e-54	206.00
IUUC-Fca-036380	Felis catus	65.00	2.00e-165	575.00
IUUC-Fal-037440	Ficedula albicollis	57.81	5.00e-17	78.60
IUUC-Gmo-038561	Gadus morhua	50.15	7.00e-78	284.00
IUUC-Gac-041319	Gasterosteus aculeatus	39.11	4.00e-87	315.00
IUUC-Hsa-045738	Homo sapiens	68.65	8.00e-159	553.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	63.97	5.00e-161	560.00
IUUC-Lch-050269	Latimeria chalumnae	42.86	1.00e-65	244.00
IUUC-Loc-052776	Lepisosteus oculatus	52.01	2.00e-83	303.00
IUUC-Laf-054269	Loxodonta africana	63.97	5.00e-161	560.00
IUUC-Mcc-055669	Macaca mulatta	68.27	8.00e-163	566.00
IUUC-Mmr-061562	Microcebus murinus	63.22	1.00e-129	456.00
IUUC-Mdo-062263	Monodelphis domestica	55.34	1.00e-142	499.00
IUUC-Mmu-064325	Mus musculus	62.81	1.00e-154	539.00
IUUC-Mpu-066385	Mustela putorius furo	64.62	7.00e-164	570.00
IUUC-Mlu-067000	Myotis lucifugus	63.65	8.00e-160	556.00
IUUC-Nle-069812	Nomascus leucogenys	67.88	4.00e-162	564.00
IUUC-Opr-070575	Ochotona princeps	93.41	2.00e-85	309.00
IUUC-Ont-072405	Oreochromis niloticus	39.02	5.00e-85	308.00
IUUC-Ocu-074358	Oryctolagus cuniculus	52.71	9.00e-124	436.00
IUUC-Ola-086403	Oryzias latipes	40.08	1.00e-89	323.00
IUUC-Oga-087986	Otolemur garnettii	64.42	2.00e-149	522.00
IUUC-Oar-089600	Ovis aries	62.50	9.00e-163	566.00
IUUC-Ptr-091224	Pan troglodytes	68.46	2.00e-158	552.00
IUUC-Pan-092739	Papio anubis	68.46	8.00e-164	570.00
IUUC-Pma-094407	Petromyzon marinus	48.14	5.00e-77	281.00
IUUC-Pfo-097161	Poecilia formosa	38.11	1.00e-81	297.00
IUUC-Pab-098627	Pongo abelii	68.65	8.00e-159	553.00
IUUC-Pca-100641	Procavia capensis	61.40	1.00e-148	519.00
IUUC-Pva-102670	Pteropus vampyrus	62.69	1.00e-154	539.00
IUUC-Rno-105504	Rattus norvegicus	62.04	9.00e-153	533.00
IUUC-Sha-107342	Sarcophilus harrisii	55.34	5.00e-148	517.00
IUUC-Sar-113425	Sorex araneus	60.35	3.00e-70	258.00
IUUC-Ssc-115904	Sus scrofa	86.91	6.00e-90	322.00
IUUC-Tru-118096	Takifugu rubripes	40.11	3.00e-91	328.00
IUUC-Tni-119873	Tetraodon nigroviridis	36.52	2.00e-84	306.00
IUUC-Tbe-127578	Tupaia belangeri	63.13	6.00e-121	427.00
IUUC-Ttr-129107	Tursiops truncatus	64.42	8.00e-148	516.00
IUUC-Vpa-130353	Vicugna pacos	66.54	1.00e-76	279.00
IUUC-Xtr-132168	Xenopus tropicalis	32.69	2.00e-43	170.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence