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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046761
Ensembl Protein ID ENSP00000347997.2
UniProt Accession Q9H347; Q9NRE0; UBQL3_HUMAN
Genbank Protein ID AAG41675.1; AAF67143.1; AAH36743.1
Protein Name Ubiquilin-3
Genbank Nucleotide ID AF137396; AF230481; BC036743
Gene Name UBQLN3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000175520.8 ENST00000311659.4 ENSP00000347997.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitemiRTarBasemicroRNA
TRANSFACTargetScanRepTarmiRcode
RAID2
Protein-protein Interaction
IID
Protein 3D Structure
PDBMMDB
Disease-associated Information
OMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UBA UBA 10831842
ULD/UDP/UBQ/UBQ_Other UBQ_Other 10831842
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UBA 1.10e-08 36.6 617 652
ULD/UDP/UBQ/UBQ_Other 2.20e-18 67.5 22 95
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UBA
   S: 4    edkleqlveMGF.dreealqaLraannnleaAveyL 38
           + +leql++MGF +re++lqaL a++++++aAve L
   Q: 617  QVQLEQLRSMGFlNREANLQALIATGGDVDAAVEKL 652
           679******************************987 PP
   

   ULD/UDP/UBQ/UBQ_Other
   S: 1    vqvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekksg 75
           ++vtvk+++++e +++v  ++t+++LKe+i+++++ +p+q  Li++GkiL+d+++La++g++dg t+hl+ k+ +
   Q: 22   IKVTVKTPKDKE-DFSVTDTCTIQQLKEEISQRFKAHPDQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKRQH 95
           6899*****985.78899****************************************************99876 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAKGGEALPQ GSPAPVQDPH LIKVTVKTPK DKEDFSVTDT CTIQQLKEEI SQRFKAHPDQ 60
LVLIFAGKIL KDPDSLAQCG VRDGLTVHLV IKRQHRAMGN ECPAASVPTQ GPSPGSLPQP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046761|UBD,UBA;ULD,UBQ_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGGACCTGA TAGTGCGGGT TCTGGCCCAG AAGGCCTCAG GGGTGGCTGT GTAGCAAGAT 60
GAGGGAGGTT TGGAGCCCTG CATAAAGAGA AGGACGGGAC CACAGCTGAC TGGTATGTAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046761|UBD,UBA;ULD,UBQ_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2
Pfam

PF00627--UBA
PF00240--ubiquitin
SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ
KEGG hsa:50613
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001302 Ailuropoda melanoleuca 77.56 0.00e+00 862.00
IUUC-Bgr-012188 Blumeria graminis 26.50 1.00e-10 61.20
IUUC-Bta-012941 Bos taurus 79.29 0.00e+00 739.00
IUUC-Cja-019387 Callithrix jacchus 88.11 0.00e+00 979.00
IUUC-Cfa-020572 Canis familiaris 79.24 0.00e+00 883.00
IUUC-Cpo-021846 Cavia porcellus 78.14 8.00e-121 427.00
IUUC-Csa-024187 Chlorocebus sabaeus 95.11 0.00e+00 1025.00
IUUC-Cho-024936 Choloepus hoffmanni 80.00 0.00e+00 899.00
IUUC-Dno-029226 Dasypus novemcinctus 79.69 0.00e+00 923.00
IUUC-Dse-031421 Dothistroma septosporum 29.18 2.00e-13 70.50
IUUC-Ete-032824 Echinops telfairi 69.51 0.00e+00 734.00
IUUC-Eca-033383 Equus caballus 75.22 0.00e+00 634.00
IUUC-Fca-035855 Felis catus 78.63 0.00e+00 843.00
IUUC-Ggo-045636 Gorilla gorilla 97.86 0.00e+00 1088.00
IUUC-Itr-049069 Ictidomys tridecemlineatus 81.98 0.00e+00 840.00
IUUC-Laf-054412 Loxodonta africana 84.81 2.00e-145 509.00
IUUC-Mcc-055310 Macaca mulatta 95.42 0.00e+00 1029.00
IUUC-Mmr-060687 Microcebus murinus 83.33 0.00e+00 874.00
IUUC-Mdo-062941 Monodelphis domestica 68.56 2.00e-122 432.00
IUUC-Mmu-063953 Mus musculus 73.40 0.00e+00 803.00
IUUC-Mpu-066645 Mustela putorius furo 87.25 5.00e-126 444.00
IUUC-Nle-069745 Nomascus leucogenys 96.18 0.00e+00 1019.00
IUUC-Ocu-073979 Oryctolagus cuniculus 79.27 0.00e+00 868.00
IUUC-Oga-088802 Otolemur garnettii 82.90 0.00e+00 898.00
IUUC-Oar-089721 Ovis aries 77.39 0.00e+00 785.00
IUUC-Ptr-091188 Pan troglodytes 87.94 0.00e+00 951.00
IUUC-Pma-094577 Petromyzon marinus 70.37 1.00e-28 117.00
IUUC-Pab-098116 Pongo abelii 97.40 0.00e+00 1079.00
IUUC-Pca-100194 Procavia capensis 71.45 6.00e-171 593.00
IUUC-Pva-102958 Pteropus vampyrus 80.25 0.00e+00 649.00
IUUC-Pte-104090 Pyrenophora teres 27.65 2.00e-08 53.90
IUUC-Pyt-104472 Pyrenophora triticirepentis 26.85 2.00e-09 57.00
IUUC-Rno-105161 Rattus norvegicus 74.96 0.00e+00 871.00
IUUC-Sha-107327 Sarcophilus harrisii 60.09 0.00e+00 647.00
IUUC-Sar-113022 Sorex araneus 74.39 0.00e+00 857.00
IUUC-Ssc-115333 Sus scrofa 74.05 2.00e-127 449.00
IUUC-Tsy-119637 Tarsius syrichta 76.23 0.00e+00 681.00
IUUC-Tbe-128150 Tupaia belangeri 76.14 4.00e-176 611.00
IUUC-Ttr-128507 Tursiops truncatus 75.42 0.00e+00 834.00
IUUC-Vpa-130797 Vicugna pacos 68.35 0.00e+00 754.00
Created Date 25-Jun-2017

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