iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033573

UUCD1 version

UUC-EqC-00467

Ensembl Protein ID

ENSECAP00000019025.1

UniProt Accession

F6XJ99; F6XJ99_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021249.1	ENSECAT00000022993.1	ENSECAP00000019025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.40e-06	27.7	29	89
E3 activity/RING/PHD	3.10e-09	37.0	793	838

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadCl...qkw........pglknssskefrCPlCr 46
           Ca+C++++    + +p++lpC H f++ Cl   ++          +   ++ + +rCP+Cr
   Q: 29   CAVCQQSLqsrrEAEPKLLPCLHSFCLRCLpepERQlsvpipggSNGDIQQVGVIRCPVCR 89
           ******999888556***************88844468888666555556667779****8 PP

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C+vC++gg+    l++CekC ++fH +C+ ++   ++p+ + wiC+ Cr+
   Q: 793  DWCAVCQNGGD----LLCCEKCPKVFHLTCHVPT-LLSFPSGD-WICTFCRD 838
           79*********....*******************.*******7.******85 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

PGPAAASAPA PGPSAGPPPG PPASLLDTCA VCQQSLQSRR EAEPKLLPCL HSFCLRCLPE 60
PERQLSVPIP GGSNGDIQQV GVIRCPVCRQ ECRQIDLVDN YFVKDTSEAP SSSDEKSEQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCGACGA CGGGGGGGGT GGCCGCGGCC TCCTCGGGCT CGGCCCCGGG CTGCCTCAGC 60
CCCTGCGGGC CTCAGTGGGC CCTGGAGTTC CGGGGGGGGC GGTATCGACG CCGGGCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR019786--Zinc_finger_PHD-type_CS
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0030514--P:negative regulation of BMP signaling pathway
GO:0016567--P:protein ubiquitination
GO:0017015--P:regulation of transforming growth factor beta receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002364	Ailuropoda melanoleuca	96.93	0.00e+00	1729.00
IUUC-Apl-003894	Anas platyrhynchos	91.48	0.00e+00	1579.00
IUUC-Aca-004658	Anolis carolinensis	89.64	0.00e+00	1543.00
IUUC-Ame-011619	Astyanax mexicanus	60.38	0.00e+00	1045.00
IUUC-Bta-013341	Bos taurus	95.84	0.00e+00	1682.00
IUUC-Cja-018733	Callithrix jacchus	97.52	0.00e+00	1745.00
IUUC-Cfa-020725	Canis familiaris	97.69	0.00e+00	1700.00
IUUC-Cpo-021833	Cavia porcellus	96.53	0.00e+00	1711.00
IUUC-Csa-023040	Chlorocebus sabaeus	97.62	0.00e+00	1687.00
IUUC-Cho-024934	Choloepus hoffmanni	94.86	0.00e+00	1605.00
IUUC-Cin-025200	Ciona intestinalis	32.48	1.00e-44	175.00
IUUC-Csv-026278	Ciona savignyi	52.70	6.00e-19	87.40
IUUC-Dre-027797	Danio rerio	72.93	4.00e-172	598.00
IUUC-Dno-028955	Dasypus novemcinctus	97.52	0.00e+00	1790.00
IUUC-Dme-032143	Drosophila melanogaster	31.64	9.00e-45	176.00
IUUC-Ete-032728	Echinops telfairi	95.33	0.00e+00	912.00
IUUC-Eeu-035138	Erinaceus europaeus	85.04	0.00e+00	823.00
IUUC-Fca-035776	Felis catus	97.69	0.00e+00	1614.00
IUUC-Fal-037583	Ficedula albicollis	89.94	0.00e+00	1605.00
IUUC-Gmo-039353	Gadus morhua	61.56	0.00e+00	659.00
IUUC-Gga-040874	Gallus gallus	92.18	0.00e+00	1687.00
IUUC-Gac-041689	Gasterosteus aculeatus	55.79	0.00e+00	1102.00
IUUC-Ggo-045151	Gorilla gorilla	96.27	0.00e+00	1303.00
IUUC-Hsa-046169	Homo sapiens	97.62	0.00e+00	1687.00
IUUC-Itr-048377	Ictidomys tridecemlineatus	97.28	0.00e+00	739.00
IUUC-Lch-050411	Latimeria chalumnae	80.76	0.00e+00	1357.00
IUUC-Loc-051992	Lepisosteus oculatus	72.03	0.00e+00	1279.00
IUUC-Laf-054552	Loxodonta africana	97.28	0.00e+00	1632.00
IUUC-Mcc-055744	Macaca mulatta	97.52	0.00e+00	1684.00
IUUC-Meu-056647	Macropus eugenii	98.30	0.00e+00	702.00
IUUC-Mga-059589	Meleagris gallopavo	91.41	0.00e+00	954.00
IUUC-Mmr-060727	Microcebus murinus	98.01	0.00e+00	1726.00
IUUC-Mdo-063029	Monodelphis domestica	94.65	0.00e+00	1724.00
IUUC-Mmu-064033	Mus musculus	96.23	0.00e+00	1748.00
IUUC-Mpu-066679	Mustela putorius furo	97.42	0.00e+00	1721.00
IUUC-Mlu-067286	Myotis lucifugus	96.33	0.00e+00	1619.00
IUUC-Nle-069156	Nomascus leucogenys	97.32	0.00e+00	1680.00
IUUC-Opr-070309	Ochotona princeps	86.95	0.00e+00	1274.00
IUUC-Ont-071586	Oreochromis niloticus	54.39	0.00e+00	1049.00
IUUC-Oan-073205	Ornithorhynchus anatinus	93.49	0.00e+00	1435.00
IUUC-Ocu-074667	Oryctolagus cuniculus	94.51	0.00e+00	1600.00
IUUC-Ola-086481	Oryzias latipes	67.23	4.00e-165	575.00
IUUC-Oga-089101	Otolemur garnettii	96.93	0.00e+00	1712.00
IUUC-Oar-090167	Ovis aries	97.03	0.00e+00	1725.00
IUUC-Ptr-090901	Pan troglodytes	97.72	0.00e+00	1690.00
IUUC-Pan-092448	Papio anubis	95.44	0.00e+00	1687.00
IUUC-Psi-093657	Pelodiscus sinensis	91.78	0.00e+00	1459.00
IUUC-Pma-094506	Petromyzon marinus	65.91	1.00e-50	191.00
IUUC-Pfo-097104	Poecilia formosa	69.40	2.00e-160	559.00
IUUC-Pab-097704	Pongo abelii	97.62	0.00e+00	1724.00
IUUC-Pca-101001	Procavia capensis	87.62	0.00e+00	645.00
IUUC-Pva-102733	Pteropus vampyrus	93.67	0.00e+00	1560.00
IUUC-Rno-105512	Rattus norvegicus	96.93	0.00e+00	1738.00
IUUC-Sha-107423	Sarcophilus harrisii	93.74	0.00e+00	1605.00
IUUC-Sar-113181	Sorex araneus	86.36	1.00e-142	501.00
IUUC-Ssc-116330	Sus scrofa	92.04	0.00e+00	1500.00
IUUC-Tgu-117388	Taeniopygia guttata	74.87	0.00e+00	1244.00
IUUC-Tru-118728	Takifugu rubripes	56.90	0.00e+00	971.00
IUUC-Tsy-119053	Tarsius syrichta	97.78	0.00e+00	1043.00
IUUC-Tni-120279	Tetraodon nigroviridis	46.00	5.00e-161	561.00
IUUC-Tbe-127573	Tupaia belangeri	87.59	0.00e+00	818.00
IUUC-Ttr-128594	Tursiops truncatus	97.03	0.00e+00	1725.00
IUUC-Vpa-130619	Vicugna pacos	91.67	0.00e+00	1093.00
IUUC-Xtr-132837	Xenopus tropicalis	84.46	0.00e+00	1491.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence