iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037333

Ensembl Protein ID

ENSFALP00000005787.1

UniProt Accession

U3JSN3; U3JSN3_FICAL

Genbank Protein ID

ENSFALP00000005787

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011072

Gene Name

UBR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005559.1	ENSFALT00000005814.1	ENSFALP00000005787.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.30e-38	130.7	173	249
E3 activity/RING/RING	1.80e-07	31.3	1051	1155
E3 activity/N-recognin/UBR-box	4.00e-29	100.6	43	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy+vLfNDE+Hsy++viyslq+Al +e+ ea++++t+idkeGRravkaG ya+c+eak+ei+++se+++q pL+Vev
   Q: 173  YYCVLFNDEHHSYDHVIYSLQRALGCELGEAQLHTTAIDKEGRRAVKAGHYAACQEAKEEIKRHSENVSQRPLHVEV 249
           9**************************************************************************97 PP

E3 activity/RING/RING

   S: 1    CaiCledf...............kd..............................gplvlpCgHvfhadClqkw............. 29
           C++C+e+                ++                              g+++++CgHv+ha C+qk+             
   Q: 1051 CILCQEEQevklesaamvlsacvQKstaltqnrsrilelsgdtldplfmhpdlpcGTHTGSCGHVMHAACWQKYfeamqlnfrqrlh 1137
           78885555333333333333333003333333333333333333333333333337999***************************9 PP
   S: 30   .pglknssskefrCPlCr 46
             +  +++++e +CPlC+
   Q: 1138 vEQIFDLENGEYLCPLCK 1155
           99999999*********7 PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCg+vfk get+y+Cr+C+vd+t+vlC +Cf++++Hk+H+yk++ s+gggfCdCGdteAw+ g+ C k+ 
   Q: 43   QLCGKVFKGGETTYSCRDCAVDPTCVLCIDCFQNSIHKNHRYKMHSSTGGGFCDCGDTEAWKAGPVCTKHA 113
           68*****************************************************************9985 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MDPLVEKQEE MVQAAILYPL ECYLFGEDPD VFLEKLQQSG TSQLCGKVFK GGETTYSCRD 60
CAVDPTCVLC IDCFQNSIHK NHRYKMHSST GGGFCDCGDT EAWKAGPVCT KHAPGASSSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTGCGATG AAAGATTCGA CTTCCAAGCT ACATTTTTAC AGTGCTTGGC AAAACATGTG 60
CCCAATATTT ATTCAGCTGA AATGGACCCC TTGGTGGAGA AACAAGAAGA AATGGTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000502--C:proteasome complex
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0032007--P:negative regulation of TOR signaling
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fab:101819886

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001354	Ailuropoda melanoleuca	77.58	0.00e+00	2704.00
IUUC-Apl-004160	Anas platyrhynchos	93.96	0.00e+00	3231.00
IUUC-Aca-004982	Anolis carolinensis	78.30	0.00e+00	2742.00
IUUC-Acl-008055	Aspergillus clavatus	25.71	2.00e-35	145.00
IUUC-Afl-008479	Aspergillus flavus	23.42	3.00e-44	174.00
IUUC-Ani-009334	Aspergillus nidulans	23.34	4.00e-47	184.00
IUUC-Aor-010124	Aspergillus oryzae	23.46	7.00e-44	173.00
IUUC-Ate-010550	Aspergillus terreus	23.82	2.00e-45	179.00
IUUC-Ame-011231	Astyanax mexicanus	59.33	0.00e+00	1953.00
IUUC-Bgr-011999	Blumeria graminis	23.98	4.00e-52	201.00
IUUC-Bta-012347	Bos taurus	77.35	0.00e+00	2699.00
IUUC-Bci-013834	Botrytis cinerea	23.79	6.00e-52	200.00
IUUC-Cja-018911	Callithrix jacchus	74.90	0.00e+00	2600.00
IUUC-Cfa-020991	Canis familiaris	78.46	0.00e+00	2730.00
IUUC-Cpo-021448	Cavia porcellus	76.49	0.00e+00	2675.00
IUUC-Cre-022930	Chlamydomonas reinhardtii	46.15	4.30e-02	29.60
IUUC-Csa-024255	Chlorocebus sabaeus	77.92	0.00e+00	2224.00
IUUC-Cho-024550	Choloepus hoffmanni	60.50	0.00e+00	1955.00
IUUC-Cne-026823	Cryptococcus neoformans	24.00	3.00e-39	157.00
IUUC-Dno-029427	Dasypus novemcinctus	77.04	0.00e+00	2628.00
IUUC-Dor-031073	Dipodomys ordii	68.64	0.00e+00	1221.00
IUUC-Ete-032318	Echinops telfairi	64.27	0.00e+00	1011.00
IUUC-Eca-033348	Equus caballus	78.23	0.00e+00	2603.00
IUUC-Eeu-034664	Erinaceus europaeus	71.09	0.00e+00	2440.00
IUUC-Fox-037984	Fusarium oxysporum	25.58	1.00e-41	166.00
IUUC-Gmo-039363	Gadus morhua	56.82	0.00e+00	1689.00
IUUC-Ggr-040070	Gaeumannomyces graminis	25.77	2.00e-43	172.00
IUUC-Gga-040486	Gallus gallus	94.16	0.00e+00	3175.00
IUUC-Gac-041985	Gasterosteus aculeatus	58.45	0.00e+00	1782.00
IUUC-Gma-043622	Glycine max	24.73	8.00e-29	123.00
IUUC-Ggo-044704	Gorilla gorilla	72.07	0.00e+00	2097.00
IUUC-Hsa-046753	Homo sapiens	78.29	0.00e+00	2729.00
IUUC-Itr-048410	Ictidomys tridecemlineatus	78.04	0.00e+00	2708.00
IUUC-Lch-049904	Latimeria chalumnae	64.14	0.00e+00	2171.00
IUUC-Lpe-051516	Leersia perrieri	26.14	2.00e-31	132.00
IUUC-Loc-052624	Lepisosteus oculatus	62.50	0.00e+00	2067.00
IUUC-Lma-053059	Leptosphaeria maculans	24.38	5.00e-51	197.00
IUUC-Laf-053857	Loxodonta africana	75.77	0.00e+00	2651.00
IUUC-Mcc-054873	Macaca mulatta	78.23	0.00e+00	2690.00
IUUC-Meu-056858	Macropus eugenii	63.27	0.00e+00	994.00
IUUC-Mor-057051	Magnaporthe oryzae	26.08	7.00e-42	167.00
IUUC-Mga-059917	Meleagris gallopavo	94.42	0.00e+00	3284.00
IUUC-Mmr-061128	Microcebus murinus	74.53	0.00e+00	2527.00
IUUC-Mdo-062306	Monodelphis domestica	78.74	0.00e+00	2736.00
IUUC-Mmu-063389	Mus musculus	77.34	0.00e+00	2701.00
IUUC-Mpu-065983	Mustela putorius furo	78.11	0.00e+00	2742.00
IUUC-Mlu-068013	Myotis lucifugus	76.14	0.00e+00	2649.00
IUUC-Nle-070031	Nomascus leucogenys	78.29	0.00e+00	2735.00
IUUC-Opr-070551	Ochotona princeps	58.61	0.00e+00	1065.00
IUUC-Ont-072035	Oreochromis niloticus	59.32	0.00e+00	2009.00
IUUC-Ocu-074930	Oryctolagus cuniculus	75.00	0.00e+00	2572.00
IUUC-Oba-075295	Oryza barthii	40.62	3.00e-15	78.60
IUUC-Obr-076117	Oryza brachyantha	25.55	7.00e-31	130.00
IUUC-Ogl-077571	Oryza glaberrima	25.22	2.00e-30	128.00
IUUC-Ogu-078497	Oryza glumaepatula	40.62	3.00e-15	78.60
IUUC-Oin-079343	Oryza indica	40.62	3.00e-15	78.60
IUUC-Oni-083099	Oryza nivara	40.62	3.00e-15	78.60
IUUC-Opu-083202	Oryza punctata	26.07	7.00e-31	130.00
IUUC-Oru-084471	Oryza rufipogon	40.62	3.00e-15	78.60
IUUC-Osa-085336	Oryza sativa	25.44	4.00e-30	126.00
IUUC-Ola-086683	Oryzias latipes	59.07	0.00e+00	1957.00
IUUC-Oga-088017	Otolemur garnettii	75.29	0.00e+00	2598.00
IUUC-Oar-089557	Ovis aries	76.94	0.00e+00	2688.00
IUUC-Ptr-091366	Pan troglodytes	77.46	0.00e+00	2705.00
IUUC-Pan-092184	Papio anubis	78.29	0.00e+00	2691.00
IUUC-Psi-093720	Pelodiscus sinensis	85.97	0.00e+00	2882.00
IUUC-Pma-094152	Petromyzon marinus	40.70	3.00e-153	535.00
IUUC-Pno-094877	Phaeosphaeria nodorum	23.77	2.00e-41	165.00
IUUC-Pfo-097124	Poecilia formosa	59.34	0.00e+00	1977.00
IUUC-Pab-098586	Pongo abelii	78.17	0.00e+00	2723.00
IUUC-Pop-099184	Populus trichocarpa	35.71	3.00e-12	66.20
IUUC-Pca-100673	Procavia capensis	71.43	0.00e+00	1402.00
IUUC-Pva-102724	Pteropus vampyrus	72.77	0.00e+00	2476.00
IUUC-Pte-104174	Pyrenophora teres	24.87	2.00e-50	195.00
IUUC-Pyt-104431	Pyrenophora triticirepentis	24.52	4.00e-50	194.00
IUUC-Rno-105474	Rattus norvegicus	74.36	0.00e+00	1962.00
IUUC-Sha-106993	Sarcophilus harrisii	78.76	0.00e+00	2750.00
IUUC-Sar-113447	Sorex araneus	76.10	0.00e+00	1803.00
IUUC-Sre-115045	Sporisorium reilianum	25.45	3.00e-47	184.00
IUUC-Ssc-115768	Sus scrofa	75.06	0.00e+00	2481.00
IUUC-Tgu-116949	Taeniopygia guttata	88.30	0.00e+00	2989.00
IUUC-Tru-117782	Takifugu rubripes	58.17	0.00e+00	1959.00
IUUC-Tsy-119177	Tarsius syrichta	69.25	0.00e+00	1872.00
IUUC-Tni-120884	Tetraodon nigroviridis	54.33	0.00e+00	1770.00
IUUC-Tre-122137	Trichoderma reesei	25.48	6.00e-60	227.00
IUUC-Tvi-122272	Trichoderma virens	24.11	1.00e-54	209.00
IUUC-Tae-125358	Triticum aestivum	25.73	7.00e-29	123.00
IUUC-Tme-127156	Tuber melanosporum	23.89	1.00e-50	196.00
IUUC-Tbe-128088	Tupaia belangeri	67.57	0.00e+00	1048.00
IUUC-Ttr-129062	Tursiops truncatus	73.08	0.00e+00	2506.00
IUUC-Uma-129344	Ustilago maydis	26.36	3.00e-50	194.00
IUUC-Vda-129778	Verticillium dahliae	27.27	6.00e-48	187.00
IUUC-Vpa-130578	Vicugna pacos	71.13	0.00e+00	2406.00
IUUC-Xtr-132244	Xenopus tropicalis	62.31	0.00e+00	2120.00
IUUC-Xma-134112	Xiphophorus maculatus	59.34	0.00e+00	1986.00
IUUC-Yli-134662	Yarrowia lipolytica	23.88	1.00e-31	133.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence