iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-041188

UUCD1 version

UUC-GaG-00875

Ensembl Protein ID

ENSGALP00000051754.2

UniProt Accession

A0A1D5PG34; A0A1D5PG34_CHICK

Genbank Protein ID

ENSGALP00000051754

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000209

Gene Name

USP8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000005894.6	ENSGALT00000078257.2	ENSGALP00000051754.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-109	366.7	775	1105

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n p l+e++++  ++ ++n++n  ++kge+++++  ++++lw+++ k++sp++++ +++k++ +f g
   Q: 775  TGLRNLGNTCYMNSILQCLCNAPHLAEYFNKnLYQDDINRSNFLGHKGEVAEEFGVIMKALWTGQYKYISPKDFKITIGKINDQFAG 861
           7****************************9989****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+qqD+qE+l fl+d+l+e+l+k +n ++ +ee++d  +l+d      a++k+k+ n+s+i+ lFqgq+ks+++cl+c+++s ++e 
   Q: 862  YSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENND--HLDDLkaaelAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEA 946
           *********************885555444444444..4444445566*************************************** PP
   S: 169  fldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvef 255
           f++lslp+ + +++   +lq+cL+ f+kee+l+++n++yc++ck ++++ kk++++klP+vL +hLkRfs++ + ++ +k++++v+f
   Q: 947  FMYLSLPLASTSKC---TLQECLRLFSKEEKLTDNNRFYCSHCKTRRDSLKKIEIWKLPPVLLVHLKRFSYDGR-WK-QKLQTSVDF 1028
           *************9...******************************************************996.55.6******** PP
   S: 256  ple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           ple Ldls++++ p+++    k+Y+L++v +H+G+l++GHY+ay+kn +++ W++fdD++V+e++ ++v++   s aY+lfY+
   Q: 1029 PLEtLDLSQYVIGPKNN---LKRYNLFSVSNHYGGLDGGHYTAYCKNASKQrWFKFDDHEVSEISASSVKS---SAAYILFYT 1105
           *************9988...69*************************88778*******************...********8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPAVASVPKE LYLCTSLKDL NQKTEIKHEK TNSTKSYVQS ALKIFKAAEE CRLDRDEEKA 60
YILYMKYVAV YNFIKKRPDF KQQQDYFHSI LGPTNLKKAI EEAERLSDSL KLRYEEAEVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGCTG TGGCATCTGT ACCTAAGGAG CTGTATCTGT GTACTTCATT GAAAGATCTC 60
AACCAGAAGA CAGAAATAAA GCATGAAAAG ACCAATAGTA CAAAGAGGTA TCTATTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00581--Rhodanese
PF00443--UCH
PF08969--USP8_dimer

SMART

SM00450--RHOD

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	83.13	0.00e+00	938.00
IUUC-Apl-003226	Anas platyrhynchos	85.97	0.00e+00	999.00
IUUC-Aca-004936	Anolis carolinensis	68.77	0.00e+00	1317.00
IUUC-Ago-007959	Ashbya gossypii	35.62	1.00e-55	211.00
IUUC-Acl-008102	Aspergillus clavatus	31.32	1.00e-52	201.00
IUUC-Afl-008604	Aspergillus flavus	31.45	7.00e-51	195.00
IUUC-Afu-009001	Aspergillus fumigatus	31.32	6.00e-52	199.00
IUUC-Ani-009291	Aspergillus nidulans	30.49	8.00e-52	199.00
IUUC-Ang-009844	Aspergillus niger	31.94	4.00e-51	196.00
IUUC-Aor-010098	Aspergillus oryzae	31.45	3.00e-50	193.00
IUUC-Ate-010585	Aspergillus terreus	29.48	3.00e-51	197.00
IUUC-Ame-010960	Astyanax mexicanus	78.33	2.00e-86	310.00
IUUC-Bta-013008	Bos taurus	82.16	0.00e+00	905.00
IUUC-Bol-015281	Brassica oleracea	38.51	4.00e-48	185.00
IUUC-Bra-017228	Brassica rapa	39.40	6.00e-50	191.00
IUUC-Cel-018482	Caenorhabditis elegans	34.69	5.00e-54	205.00
IUUC-Cja-019173	Callithrix jacchus	83.30	0.00e+00	944.00
IUUC-Cfa-021243	Canis familiaris	82.96	0.00e+00	934.00
IUUC-Cpo-021522	Cavia porcellus	71.50	0.00e+00	1435.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	44.35	3.00e-82	298.00
IUUC-Csa-023616	Chlorocebus sabaeus	82.96	0.00e+00	934.00
IUUC-Cho-024381	Choloepus hoffmanni	71.05	0.00e+00	752.00
IUUC-Cin-025287	Ciona intestinalis	50.38	3.00e-99	356.00
IUUC-Csv-026253	Ciona savignyi	49.62	5.00e-89	322.00
IUUC-Cne-026821	Cryptococcus neoformans	40.72	8.00e-76	279.00
IUUC-Dre-028440	Danio rerio	67.24	0.00e+00	734.00
IUUC-Dno-029039	Dasypus novemcinctus	72.35	0.00e+00	1502.00
IUUC-Dor-031043	Dipodomys ordii	91.38	7.00e-128	451.00
IUUC-Dse-031463	Dothistroma septosporum	27.78	3.00e-41	163.00
IUUC-Dme-032089	Drosophila melanogaster	45.91	4.00e-85	309.00
IUUC-Ete-033040	Echinops telfairi	66.54	0.00e+00	1280.00
IUUC-Eca-033449	Equus caballus	82.61	0.00e+00	947.00
IUUC-Eeu-034693	Erinaceus europaeus	91.38	1.00e-123	437.00
IUUC-Fca-035794	Felis catus	90.95	0.00e+00	860.00
IUUC-Fal-037322	Ficedula albicollis	85.70	0.00e+00	1766.00
IUUC-Gmo-038584	Gadus morhua	63.64	0.00e+00	675.00
IUUC-Gac-041850	Gasterosteus aculeatus	74.95	0.00e+00	738.00
IUUC-Ggo-045565	Gorilla gorilla	83.13	0.00e+00	941.00
IUUC-Hsa-046438	Homo sapiens	83.13	0.00e+00	940.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	72.60	0.00e+00	1449.00
IUUC-Kpa-049321	Komagataella pastoris	33.51	8.00e-50	191.00
IUUC-Lch-050485	Latimeria chalumnae	85.28	0.00e+00	851.00
IUUC-Loc-052769	Lepisosteus oculatus	74.66	0.00e+00	780.00
IUUC-Lma-053021	Leptosphaeria maculans	31.99	8.00e-55	209.00
IUUC-Laf-053432	Loxodonta africana	76.58	0.00e+00	893.00
IUUC-Mcc-055823	Macaca mulatta	82.96	0.00e+00	940.00
IUUC-Meu-056099	Macropus eugenii	94.42	5.00e-160	558.00
IUUC-Mla-059089	Melampsora laricipopulina	41.10	1.00e-72	268.00
IUUC-Mga-059739	Meleagris gallopavo	96.80	0.00e+00	1079.00
IUUC-Mvi-060559	Microbotryum violaceum	41.59	3.00e-79	290.00
IUUC-Mmr-061158	Microcebus murinus	82.06	0.00e+00	920.00
IUUC-Mdo-061801	Monodelphis domestica	85.14	0.00e+00	936.00
IUUC-Mmu-063665	Mus musculus	69.27	0.00e+00	1404.00
IUUC-Mpu-066738	Mustela putorius furo	83.30	0.00e+00	937.00
IUUC-Mlu-067307	Myotis lucifugus	81.28	0.00e+00	940.00
IUUC-Nfi-068410	Neosartorya fischeri	31.39	3.00e-52	200.00
IUUC-Nle-069314	Nomascus leucogenys	82.96	0.00e+00	939.00
IUUC-Opr-070378	Ochotona princeps	61.24	0.00e+00	898.00
IUUC-Ont-071545	Oreochromis niloticus	76.83	0.00e+00	764.00
IUUC-Oan-073537	Ornithorhynchus anatinus	71.11	0.00e+00	1425.00
IUUC-Ocu-074193	Oryctolagus cuniculus	72.40	0.00e+00	1469.00
IUUC-Ola-086622	Oryzias latipes	75.97	0.00e+00	741.00
IUUC-Oga-088271	Otolemur garnettii	81.36	0.00e+00	926.00
IUUC-Oar-090431	Ovis aries	82.16	0.00e+00	910.00
IUUC-Ptr-091339	Pan troglodytes	73.17	0.00e+00	1534.00
IUUC-Pan-091783	Papio anubis	65.76	2.00e-175	608.00
IUUC-Psi-093187	Pelodiscus sinensis	71.22	3.00e-176	612.00
IUUC-Pma-094626	Petromyzon marinus	57.55	3.00e-142	498.00
IUUC-Pno-094986	Phaeosphaeria nodorum	30.51	7.00e-40	159.00
IUUC-Pfo-096463	Poecilia formosa	76.22	0.00e+00	761.00
IUUC-Pab-097645	Pongo abelii	83.30	0.00e+00	942.00
IUUC-Pva-103222	Pteropus vampyrus	88.74	0.00e+00	704.00
IUUC-Pgr-103408	Puccinia graminis	36.59	3.00e-55	210.00
IUUC-Ptt-103699	Puccinia triticina	46.50	1.00e-67	251.00
IUUC-Pte-104348	Pyrenophora teres	29.13	3.00e-42	166.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	30.75	3.00e-53	203.00
IUUC-Rno-105510	Rattus norvegicus	68.95	0.00e+00	1426.00
IUUC-Sce-106166	Saccharomyces cerevisiae	35.54	1.00e-51	197.00
IUUC-Sha-106879	Sarcophilus harrisii	84.84	0.00e+00	939.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	35.04	2.00e-50	193.00
IUUC-Sar-113019	Sorex araneus	68.51	0.00e+00	1381.00
IUUC-Sre-115031	Sporisorium reilianum	36.98	5.00e-70	259.00
IUUC-Ssc-116334	Sus scrofa	72.02	0.00e+00	1453.00
IUUC-Tgu-117062	Taeniopygia guttata	89.90	0.00e+00	1029.00
IUUC-Tru-117908	Takifugu rubripes	76.43	0.00e+00	752.00
IUUC-Tsy-118867	Tarsius syrichta	75.30	0.00e+00	825.00
IUUC-Tni-120206	Tetraodon nigroviridis	75.00	0.00e+00	734.00
IUUC-Tme-127144	Tuber melanosporum	40.00	1.00e-79	291.00
IUUC-Tbe-127877	Tupaia belangeri	91.50	5.00e-78	285.00
IUUC-Ttr-128580	Tursiops truncatus	82.09	0.00e+00	920.00
IUUC-Uma-129340	Ustilago maydis	37.85	2.00e-73	271.00
IUUC-Vpa-130541	Vicugna pacos	80.59	0.00e+00	902.00
IUUC-Xtr-132161	Xenopus tropicalis	76.95	0.00e+00	794.00
IUUC-Xma-134271	Xiphophorus maculatus	75.41	0.00e+00	754.00
IUUC-Yli-134561	Yarrowia lipolytica	36.44	2.00e-61	231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence