iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054037

Ensembl Protein ID

ENSLAFP00000027528.1

UniProt Accession

G3UI70; G3UI70_LOXAF

Protein Name

Uncharacterized protein

Gene Name

DNMBP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000030951.1	ENSLAFT00000036809.1	ENSLAFP00000024001.1
ENSLAFG00000030951.1	ENSLAFT00000037040.1	ENSLAFP00000027528.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-47	159.8	248	298

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++ly ++a + +eL ++ Gd+++++   + + gWl+g   l+g+ G+fP  Fv+
   Q: 248  GIALYRFQALEPNELDFEVGDKIRIL--GTLEDGWLEG--SLKGRTGIFPYRFVK 298
           689***********************..88899*****..9*************8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MEPGSVVRAI FDFCPSVSEE LPLFVGDIIE VLAVIDEFWL LGKKEDVTGQ FPSSFVEIVT 60
IPSLKEGERL FVCICEFTSQ ELNSLPLHRG DLVILDGSPT AGWLQGRSCW GARGFFPSSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCTG GCTCAGTGGT TCGTGCTATC TTTGACTTCT GTCCAAGTGT ATCTGAAGAA 60
CTGCCCCTCT TTGTGGGAGA TATTATCGAG GTGCTGGCAG TGATCGACGA ATTTTGGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	80.15	0.00e+00	2293.00
IUUC-Apl-003934	Anas platyrhynchos	75.28	0.00e+00	1017.00
IUUC-Aca-005005	Anolis carolinensis	67.78	0.00e+00	1090.00
IUUC-Ame-011361	Astyanax mexicanus	57.75	0.00e+00	954.00
IUUC-Bta-013210	Bos taurus	80.80	0.00e+00	2324.00
IUUC-Cel-018396	Caenorhabditis elegans	24.04	2.00e-25	112.00
IUUC-Cja-019104	Callithrix jacchus	80.65	0.00e+00	2309.00
IUUC-Cfa-020960	Canis familiaris	80.68	0.00e+00	2299.00
IUUC-Cpo-022440	Cavia porcellus	77.36	0.00e+00	2251.00
IUUC-Csa-023391	Chlorocebus sabaeus	82.59	0.00e+00	2419.00
IUUC-Cho-024795	Choloepus hoffmanni	75.80	0.00e+00	2061.00
IUUC-Cin-025137	Ciona intestinalis	33.16	7.00e-31	126.00
IUUC-Dre-027932	Danio rerio	62.62	0.00e+00	847.00
IUUC-Dno-029750	Dasypus novemcinctus	82.95	0.00e+00	2464.00
IUUC-Dor-031109	Dipodomys ordii	76.13	0.00e+00	2073.00
IUUC-Ete-032660	Echinops telfairi	77.29	0.00e+00	1887.00
IUUC-Eca-033433	Equus caballus	81.33	0.00e+00	2259.00
IUUC-Eeu-034929	Erinaceus europaeus	76.21	0.00e+00	1384.00
IUUC-Fca-035859	Felis catus	82.02	0.00e+00	2370.00
IUUC-Fal-036653	Ficedula albicollis	69.51	0.00e+00	1112.00
IUUC-Gmo-038948	Gadus morhua	62.17	0.00e+00	776.00
IUUC-Gga-040279	Gallus gallus	67.84	0.00e+00	1091.00
IUUC-Gac-041641	Gasterosteus aculeatus	56.96	0.00e+00	931.00
IUUC-Ggo-045005	Gorilla gorilla	96.15	5.00e-58	216.00
IUUC-Hsa-046063	Homo sapiens	82.96	0.00e+00	2425.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	80.91	0.00e+00	2391.00
IUUC-Lch-049865	Latimeria chalumnae	47.64	0.00e+00	1105.00
IUUC-Lpe-050758	Leersia perrieri	31.40	3.30e-02	33.50
IUUC-Loc-051754	Lepisosteus oculatus	54.11	0.00e+00	1070.00
IUUC-Mcc-055002	Macaca mulatta	83.08	0.00e+00	2433.00
IUUC-Meu-056420	Macropus eugenii	65.03	0.00e+00	1368.00
IUUC-Mga-059868	Meleagris gallopavo	68.24	0.00e+00	1104.00
IUUC-Mmr-060767	Microcebus murinus	81.27	0.00e+00	2382.00
IUUC-Mdo-061939	Monodelphis domestica	68.24	0.00e+00	1915.00
IUUC-Mmu-063980	Mus musculus	71.71	0.00e+00	2042.00
IUUC-Mpu-065913	Mustela putorius furo	80.34	0.00e+00	2352.00
IUUC-Mlu-067340	Myotis lucifugus	80.78	0.00e+00	2274.00
IUUC-Nle-069343	Nomascus leucogenys	82.59	0.00e+00	2382.00
IUUC-Opr-070694	Ochotona princeps	74.81	0.00e+00	2149.00
IUUC-Ont-071844	Oreochromis niloticus	57.85	0.00e+00	911.00
IUUC-Oan-073605	Ornithorhynchus anatinus	44.23	4.00e-36	145.00
IUUC-Ocu-074406	Oryctolagus cuniculus	77.44	0.00e+00	2237.00
IUUC-Ola-087343	Oryzias latipes	57.65	0.00e+00	676.00
IUUC-Oga-088847	Otolemur garnettii	81.21	0.00e+00	2325.00
IUUC-Oar-089817	Ovis aries	79.17	0.00e+00	2273.00
IUUC-Ptr-090508	Pan troglodytes	28.97	1.00e-63	238.00
IUUC-Pan-092104	Papio anubis	82.90	0.00e+00	2430.00
IUUC-Psi-094045	Pelodiscus sinensis	66.55	1.00e-93	337.00
IUUC-Pma-094663	Petromyzon marinus	40.99	2.00e-145	510.00
IUUC-Pfo-096714	Poecilia formosa	52.58	0.00e+00	894.00
IUUC-Pab-097918	Pongo abelii	82.77	0.00e+00	2419.00
IUUC-Pca-101096	Procavia capensis	85.02	0.00e+00	1442.00
IUUC-Pva-102490	Pteropus vampyrus	82.65	0.00e+00	2439.00
IUUC-Rno-105908	Rattus norvegicus	72.11	0.00e+00	2024.00
IUUC-Sha-107509	Sarcophilus harrisii	67.84	0.00e+00	1788.00
IUUC-Ssc-115250	Sus scrofa	79.38	0.00e+00	2212.00
IUUC-Tru-118279	Takifugu rubripes	51.41	0.00e+00	958.00
IUUC-Tni-120459	Tetraodon nigroviridis	60.78	0.00e+00	731.00
IUUC-Tbe-127753	Tupaia belangeri	67.14	0.00e+00	1006.00
IUUC-Ttr-129096	Tursiops truncatus	81.92	0.00e+00	1690.00
IUUC-Vpa-130643	Vicugna pacos	80.95	0.00e+00	1986.00
IUUC-Xtr-131979	Xenopus tropicalis	54.71	0.00e+00	1552.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence