iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000004080.2	ENSMMUT00000005789.2	ENSMMUP00000005451.2
ENSMMUG00000004080.2	ENSMMUT00000065316.1	ENSMMUP00000048663.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-39	133.8	220	258
UBD/Beta-Prp	3.20e-52	178.7	85	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 220  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 258
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  ++ l+t++     
   Q: 85   TRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRv 173
           56899****************************************************************************99877666 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + +n ++++s D+t+ lWd++tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t+
   Q: 174  srELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 260
           779*************99.7778999********************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +gh++ ++ v+f+pn+  + +gs+D + r++dlr ++ l ++++ n
   Q: 261  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 306
           ***************************************9999854 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MLGPLPGSLH PPGLGPAARS CLPQPPSRGP QPPPTPPHGP GAMSELEQLR QEAEQLRNQI 60
RVRACPATWA SLTGLDPVGR IQMRTRRTLR GHLAKIYAMH WGTDSRLLVS ASQDGKLIIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGGGTC CTCTGCCGGG ATGCAGAAGG GTGGGGAATT CTCCTTCAAT GGCCGGCTCC 60
CACTGCACCT GCACCTCTGG TGAAGTTTTC CCCAGGCCCC CCAAGCAGAG TCCAGTGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR023302--Pept_S9A_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001395	Ailuropoda melanoleuca	99.02	9.00e-180	622.00
IUUC-Bta-013430	Bos taurus	100.00	0.00e+00	630.00
IUUC-Bol-015759	Brassica oleracea	48.49	2.00e-81	298.00
IUUC-Cja-019794	Callithrix jacchus	100.00	0.00e+00	630.00
IUUC-Cpo-021865	Cavia porcellus	96.77	0.00e+00	642.00
IUUC-Csa-023572	Chlorocebus sabaeus	100.00	0.00e+00	630.00
IUUC-Dno-029001	Dasypus novemcinctus	95.50	0.00e+00	650.00
IUUC-Dor-030322	Dipodomys ordii	88.20	4.00e-156	543.00
IUUC-Eca-034149	Equus caballus	100.00	0.00e+00	630.00
IUUC-Fca-036537	Felis catus	100.00	0.00e+00	630.00
IUUC-Ggo-044543	Gorilla gorilla	100.00	0.00e+00	630.00
IUUC-Hsa-046432	Homo sapiens	100.00	0.00e+00	630.00
IUUC-Itr-048049	Ictidomys tridecemlineatus	96.40	0.00e+00	649.00
IUUC-Laf-053865	Loxodonta africana	96.77	0.00e+00	642.00
IUUC-Meu-056902	Macropus eugenii	99.34	0.00e+00	627.00
IUUC-Mmr-061015	Microcebus murinus	100.00	0.00e+00	630.00
IUUC-Mdo-062734	Monodelphis domestica	99.34	0.00e+00	627.00
IUUC-Mmu-063737	Mus musculus	95.76	0.00e+00	643.00
IUUC-Mpu-066784	Mustela putorius furo	100.00	0.00e+00	630.00
IUUC-Mlu-067912	Myotis lucifugus	99.67	0.00e+00	628.00
IUUC-Opr-070866	Ochotona princeps	100.00	0.00e+00	630.00
IUUC-Ocu-074344	Oryctolagus cuniculus	100.00	0.00e+00	630.00
IUUC-Oga-089046	Otolemur garnettii	100.00	0.00e+00	630.00
IUUC-Ptr-091444	Pan troglodytes	100.00	0.00e+00	630.00
IUUC-Pan-092045	Papio anubis	100.00	0.00e+00	630.00
IUUC-Pma-094748	Petromyzon marinus	90.87	1.00e-138	485.00
IUUC-Pab-097601	Pongo abelii	99.34	0.00e+00	627.00
IUUC-Pca-100940	Procavia capensis	100.00	0.00e+00	630.00
IUUC-Pva-102229	Pteropus vampyrus	97.16	0.00e+00	630.00
IUUC-Rno-106104	Rattus norvegicus	100.00	0.00e+00	630.00
IUUC-Sha-107632	Sarcophilus harrisii	99.34	0.00e+00	627.00
IUUC-Ssc-115595	Sus scrofa	100.00	0.00e+00	630.00
IUUC-Tbe-128132	Tupaia belangeri	99.22	6.00e-148	516.00
IUUC-Ttr-128403	Tursiops truncatus	100.00	0.00e+00	630.00
IUUC-Vda-129855	Verticillium dahliae	70.16	1.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence