iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052448

Ensembl Protein ID

ENSLOCP00000003562.1

UniProt Accession

W5M5A4; W5M5A4_LEPOC

Genbank Protein ID

ENSLOCP00000003562

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01018220

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000003011.1	ENSLOCT00000003569.1	ENSLOCP00000003562.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.00e-41	140.5	632	767

Active Site

Position(s)	Description	Evidence
808	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 136  gldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeei 224
           g +lt++   ++l++ + +eL++gG ++ Vt e+++e+++lv ++rl+e  +eq++a+++G+ +v+p+ +l+l+t++ele  +cG++ei
   Q: 632  GQELTYT---TLLSDGRMVELVSGGGSTAVTFEDRREFIRLVQKARLEE-NREQIAAMQAGLVKVVPQAVLDLLTWQELEKKVCGDPEI 716
           3444443...458888999*****************************9.9************************************** PP
   S: 225  dvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPl 276
           +ve+lk+ t+y++ ++++++ +q++we+l +f++e+r++fL+FvTg+srlP+
   Q: 717  TVEALKRLTRYED-LEQSDERVQYLWEALTNFTNEDRSRFLRFVTGRSRLPA 767
           ***********76.*************************************7 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

AVAAEDMSPG ENSHVLLGRI RFLVECIDCF RNSKPLPASL CFVPKEVCYK ICKDSSSGAN 60
APAGASSCSS SAGKSLVSVW ESPSQAPQSK KLFKFNIEPK KGTCIRTTGE EYCNSYGLWV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTAGCGG CTGAAGACAT GTCACCGGGC GAAAACTCCC ACGTCCTCCT GGGAAGGATC 60
CGCTTCCTAG TCGAGTGCAT CGACTGTTTC CGAAACAGCA AGCCGCTGCC GGCCAGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	61.58	0.00e+00	1043.00
IUUC-Apl-003715	Anas platyrhynchos	70.11	0.00e+00	1055.00
IUUC-Aca-004377	Anolis carolinensis	65.59	0.00e+00	1131.00
IUUC-Ame-011918	Astyanax mexicanus	67.25	0.00e+00	1125.00
IUUC-Bta-012736	Bos taurus	62.16	0.00e+00	1055.00
IUUC-Cja-019926	Callithrix jacchus	62.27	0.00e+00	1055.00
IUUC-Cfa-020753	Canis familiaris	66.90	0.00e+00	778.00
IUUC-Cpo-021415	Cavia porcellus	62.04	0.00e+00	1050.00
IUUC-Csa-023096	Chlorocebus sabaeus	62.04	0.00e+00	1050.00
IUUC-Dre-028746	Danio rerio	73.87	0.00e+00	1201.00
IUUC-Dno-029293	Dasypus novemcinctus	65.54	0.00e+00	696.00
IUUC-Dor-031113	Dipodomys ordii	67.43	0.00e+00	827.00
IUUC-Ete-032601	Echinops telfairi	60.47	0.00e+00	893.00
IUUC-Eca-034198	Equus caballus	60.59	0.00e+00	1040.00
IUUC-Eeu-034708	Erinaceus europaeus	63.86	1.00e-159	557.00
IUUC-Fca-035478	Felis catus	62.38	0.00e+00	1047.00
IUUC-Fal-037366	Ficedula albicollis	65.55	0.00e+00	1112.00
IUUC-Gmo-039020	Gadus morhua	72.23	0.00e+00	941.00
IUUC-Gga-040332	Gallus gallus	67.56	0.00e+00	1162.00
IUUC-Gac-042336	Gasterosteus aculeatus	72.47	0.00e+00	1244.00
IUUC-Ggo-045382	Gorilla gorilla	62.04	0.00e+00	1051.00
IUUC-Hsa-046562	Homo sapiens	62.04	0.00e+00	1051.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	62.04	0.00e+00	1050.00
IUUC-Lch-049606	Latimeria chalumnae	63.38	1.00e-157	549.00
IUUC-Laf-054507	Loxodonta africana	61.85	0.00e+00	1073.00
IUUC-Mcc-055690	Macaca mulatta	62.04	0.00e+00	1050.00
IUUC-Meu-055970	Macropus eugenii	62.79	0.00e+00	1055.00
IUUC-Mga-059654	Meleagris gallopavo	70.20	0.00e+00	1040.00
IUUC-Mmr-061069	Microcebus murinus	62.16	0.00e+00	1054.00
IUUC-Mdo-062547	Monodelphis domestica	64.55	3.00e-151	528.00
IUUC-Mmu-063096	Mus musculus	62.16	0.00e+00	1056.00
IUUC-Mpu-065846	Mustela putorius furo	61.70	0.00e+00	1049.00
IUUC-Mlu-067992	Myotis lucifugus	65.76	0.00e+00	1020.00
IUUC-Nle-069565	Nomascus leucogenys	62.22	0.00e+00	994.00
IUUC-Opr-070853	Ochotona princeps	77.12	2.00e-151	529.00
IUUC-Ont-071628	Oreochromis niloticus	73.22	0.00e+00	1215.00
IUUC-Ocu-074094	Oryctolagus cuniculus	62.39	0.00e+00	1055.00
IUUC-Ola-087384	Oryzias latipes	72.19	0.00e+00	1236.00
IUUC-Oga-088224	Otolemur garnettii	61.93	0.00e+00	1052.00
IUUC-Oar-090043	Ovis aries	60.65	0.00e+00	991.00
IUUC-Ptr-090852	Pan troglodytes	61.81	0.00e+00	1043.00
IUUC-Pan-092787	Papio anubis	62.04	0.00e+00	1052.00
IUUC-Psi-092986	Pelodiscus sinensis	60.37	0.00e+00	790.00
IUUC-Pma-094416	Petromyzon marinus	36.02	3.00e-141	496.00
IUUC-Pfo-096720	Poecilia formosa	73.40	0.00e+00	1262.00
IUUC-Pab-098325	Pongo abelii	66.50	0.00e+00	779.00
IUUC-Pca-100885	Procavia capensis	66.37	8.00e-175	607.00
IUUC-Pva-102829	Pteropus vampyrus	57.27	0.00e+00	630.00
IUUC-Rno-104882	Rattus norvegicus	62.50	0.00e+00	1058.00
IUUC-Sha-106811	Sarcophilus harrisii	80.19	6.00e-104	370.00
IUUC-Sar-113020	Sorex araneus	52.59	5.00e-112	398.00
IUUC-Ssc-115436	Sus scrofa	72.26	6.00e-119	420.00
IUUC-Tgu-117042	Taeniopygia guttata	68.10	0.00e+00	1162.00
IUUC-Tru-118419	Takifugu rubripes	69.62	0.00e+00	1142.00
IUUC-Tsy-118829	Tarsius syrichta	73.40	0.00e+00	763.00
IUUC-Tni-120410	Tetraodon nigroviridis	63.79	0.00e+00	994.00
IUUC-Tbe-128113	Tupaia belangeri	62.50	3.00e-132	465.00
IUUC-Ttr-128167	Tursiops truncatus	59.17	0.00e+00	979.00
IUUC-Xtr-132910	Xenopus tropicalis	57.00	0.00e+00	944.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence