iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036418

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02006336

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000000250.3	ENSFCAT00000000250.3	ENSFCAP00000000229.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.46	0.00e+00	694.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

FSPSSLAPDF IMWATCCNWF CLDGQPEEVP PPQGARTQAY SNPGYSSFPS PTGSEPSCKA 60
CGAHFANMAR KQTCLDCKKN FCLSCSSQVG NGPRLCLLCQ RFRATAFRRE ELMKMKVKDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCCCCTT CCTCCCTCGC ACCAGATTTT ATCATGTGGG CAACCTGCTG CAACTGGTTC 60
TGCCTGGATG GACAGCCTGA GGAGGTCCCC CCGCCCCAGG GAGCCAGGAC GCAGGCCTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	90.91	0.00e+00	657.00
IUUC-Apl-004124	Anas platyrhynchos	66.03	3.00e-123	434.00
IUUC-Aly-005548	Arabidopsis lyrata	43.75	8.00e-09	55.80
IUUC-Ame-011616	Astyanax mexicanus	59.18	4.00e-105	374.00
IUUC-Bta-012374	Bos taurus	87.23	0.00e+00	646.00
IUUC-Cja-019780	Callithrix jacchus	89.01	0.00e+00	653.00
IUUC-Cfa-021252	Canis familiaris	92.62	0.00e+00	654.00
IUUC-Cpo-022047	Cavia porcellus	87.40	0.00e+00	648.00
IUUC-Csa-023161	Chlorocebus sabaeus	90.91	0.00e+00	692.00
IUUC-Cho-024316	Choloepus hoffmanni	88.12	2.00e-152	531.00
IUUC-Dre-028596	Danio rerio	55.37	8.00e-109	386.00
IUUC-Dno-029333	Dasypus novemcinctus	91.74	0.00e+00	664.00
IUUC-Ete-033163	Echinops telfairi	84.30	4.00e-166	577.00
IUUC-Eca-033994	Equus caballus	91.53	0.00e+00	675.00
IUUC-Eeu-035162	Erinaceus europaeus	83.00	1.00e-125	442.00
IUUC-Fal-037427	Ficedula albicollis	67.03	8.00e-135	473.00
IUUC-Gga-041053	Gallus gallus	68.04	2.00e-131	462.00
IUUC-Ggo-045436	Gorilla gorilla	91.46	0.00e+00	694.00
IUUC-Hsa-045798	Homo sapiens	91.46	0.00e+00	694.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	89.30	0.00e+00	646.00
IUUC-Lch-050639	Latimeria chalumnae	61.98	4.00e-125	441.00
IUUC-Laf-053355	Loxodonta africana	86.99	3.00e-179	620.00
IUUC-Mcc-055222	Macaca mulatta	90.91	0.00e+00	645.00
IUUC-Meu-056692	Macropus eugenii	77.69	3.00e-158	550.00
IUUC-Mga-059298	Meleagris gallopavo	67.12	7.00e-131	460.00
IUUC-Mmr-061792	Microcebus murinus	90.08	0.00e+00	644.00
IUUC-Mdo-062986	Monodelphis domestica	79.84	7.00e-169	586.00
IUUC-Mmu-063356	Mus musculus	87.98	0.00e+00	646.00
IUUC-Mpu-066273	Mustela putorius furo	93.32	0.00e+00	722.00
IUUC-Mlu-066953	Myotis lucifugus	91.26	0.00e+00	683.00
IUUC-Nle-070075	Nomascus leucogenys	90.98	0.00e+00	701.00
IUUC-Opr-070838	Ochotona princeps	89.26	0.00e+00	641.00
IUUC-Ont-071967	Oreochromis niloticus	50.69	9.00e-92	330.00
IUUC-Ocu-074807	Oryctolagus cuniculus	90.44	0.00e+00	681.00
IUUC-Ola-086903	Oryzias latipes	49.22	9.00e-90	323.00
IUUC-Oga-088536	Otolemur garnettii	88.98	2.00e-176	611.00
IUUC-Oar-089838	Ovis aries	87.43	0.00e+00	630.00
IUUC-Ptr-090962	Pan troglodytes	91.18	0.00e+00	694.00
IUUC-Pan-092853	Papio anubis	90.36	0.00e+00	688.00
IUUC-Psi-093164	Pelodiscus sinensis	65.75	2.00e-126	445.00
IUUC-Pma-094104	Petromyzon marinus	43.51	4.00e-56	211.00
IUUC-Pno-094968	Phaeosphaeria nodorum	38.78	7.00e-09	57.40
IUUC-Pab-098304	Pongo abelii	91.26	0.00e+00	699.00
IUUC-Pca-100316	Procavia capensis	90.08	0.00e+00	629.00
IUUC-Pva-102612	Pteropus vampyrus	77.96	8.00e-160	556.00
IUUC-Rno-105449	Rattus norvegicus	87.88	0.00e+00	631.00
IUUC-Sha-107578	Sarcophilus harrisii	79.73	1.00e-156	545.00
IUUC-Sar-113638	Sorex araneus	86.78	3.00e-176	610.00
IUUC-Ssc-116401	Sus scrofa	90.71	0.00e+00	692.00
IUUC-Tru-118765	Takifugu rubripes	48.64	2.00e-80	292.00
IUUC-Tsy-118850	Tarsius syrichta	87.46	1.00e-151	528.00
IUUC-Tbe-128086	Tupaia belangeri	82.37	7.00e-176	609.00
IUUC-Ttr-128249	Tursiops truncatus	82.46	5.00e-97	347.00
IUUC-Vpa-130816	Vicugna pacos	87.21	6.00e-41	160.00
IUUC-Xtr-132262	Xenopus tropicalis	42.31	8.00e-68	250.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence