iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093765

Ensembl Protein ID

ENSPSIP00000010170.1

UniProt Accession

K7FQ60; K7FQ60_PELSI

Genbank Protein ID

ENSPSIP00000010170

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01174074

Gene Name

GRB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000009206.1	ENSPSIT00000010222.1	ENSPSIP00000010170.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-36	124.6	157	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +  +vq+l+d+++q+++eL +++Gd+++v+  ++ d +W+kg    +g+ G+fP n+v+ ++
   Q: 157  QPTYVQALFDFDPQEEGELGFRRGDFIQVL--DNSDPNWWKG--ACHGQTGMFPRNYVTPVN 214
           5689**************************..9*********..8**************997 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MEAIAKYDFK ATADDELSFK RGDILKVLNE ECDQNWYKAE LNGKDGFIPK NYIEMKPHPW 60
FFGKIPRAKA EEVLGKQRHD GAFLIRESES APGDFSLSVK FGNDVQHFKV LRDGAGKYFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGGAAAG CGGAAGCGGC GGCCGGGTCT GGCTCGGGAG GAGGGAGAGG AGCAGGGCGC 60
GGCCCCTGCC ATCCGTCCGT GCCACACTTC CCCTGATGGT CGGTCTCTTC CTCCACCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0070436--C:Grb2-EGFR complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0012506--C:vesicle membrane
GO:0003723--F:RNA binding
GO:0048646--P:anatomical structure formation involved in morphogenesis
GO:0030154--P:cell differentiation
GO:0071479--P:cellular response to ionizing radiation
GO:0008286--P:insulin receptor signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0009967--P:positive regulation of signal transduction
GO:0031623--P:receptor internalization
GO:0043408--P:regulation of MAPK cascade
GO:0042770--P:signal transduction in response to DNA damage

KEGG

pss:102463609

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001345	Ailuropoda melanoleuca	96.35	2.00e-111	394.00
IUUC-Apl-003322	Anas platyrhynchos	99.48	2.00e-113	400.00
IUUC-Aca-005193	Anolis carolinensis	99.08	1.00e-128	451.00
IUUC-Ago-007965	Ashbya gossypii	50.00	5.00e-13	67.80
IUUC-Ame-010929	Astyanax mexicanus	92.17	3.00e-121	427.00
IUUC-Bta-012932	Bos taurus	97.24	9.00e-127	445.00
IUUC-Cel-018665	Caenorhabditis elegans	58.06	1.00e-71	262.00
IUUC-Cja-019225	Callithrix jacchus	97.24	9.00e-127	445.00
IUUC-Cfa-020887	Canis familiaris	97.24	9.00e-127	445.00
IUUC-Cpo-022488	Cavia porcellus	97.24	9.00e-127	445.00
IUUC-Csa-023326	Chlorocebus sabaeus	97.24	9.00e-127	445.00
IUUC-Cho-024953	Choloepus hoffmanni	79.26	3.00e-95	340.00
IUUC-Cin-025144	Ciona intestinalis	63.21	6.00e-74	269.00
IUUC-Csv-026210	Ciona savignyi	60.66	1.00e-71	261.00
IUUC-Dre-028403	Danio rerio	95.39	7.00e-125	439.00
IUUC-Dno-029187	Dasypus novemcinctus	95.85	1.00e-125	441.00
IUUC-Dor-030763	Dipodomys ordii	97.24	9.00e-127	445.00
IUUC-Dme-031741	Drosophila melanogaster	65.09	5.00e-78	283.00
IUUC-Ete-032354	Echinops telfairi	68.52	9.00e-81	292.00
IUUC-Eca-033222	Equus caballus	97.24	9.00e-127	445.00
IUUC-Eeu-034513	Erinaceus europaeus	70.97	2.00e-85	307.00
IUUC-Fca-036294	Felis catus	97.24	9.00e-127	445.00
IUUC-Fal-037130	Ficedula albicollis	98.62	3.00e-127	446.00
IUUC-Gmo-039546	Gadus morhua	94.47	2.00e-123	434.00
IUUC-Gga-041139	Gallus gallus	99.54	8.00e-129	452.00
IUUC-Gac-041968	Gasterosteus aculeatus	95.39	2.00e-124	437.00
IUUC-Ggo-044562	Gorilla gorilla	97.24	9.00e-127	445.00
IUUC-Hsa-046730	Homo sapiens	97.24	9.00e-127	445.00
IUUC-Itr-049025	Ictidomys tridecemlineatus	97.24	9.00e-127	445.00
IUUC-Lch-050230	Latimeria chalumnae	95.52	1.00e-73	269.00
IUUC-Loc-052723	Lepisosteus oculatus	95.85	3.00e-125	440.00
IUUC-Laf-053774	Loxodonta africana	95.85	1.00e-125	441.00
IUUC-Mcc-054603	Macaca mulatta	97.24	9.00e-127	445.00
IUUC-Meu-056173	Macropus eugenii	81.57	1.00e-100	358.00
IUUC-Mga-059950	Meleagris gallopavo	99.54	8.00e-129	452.00
IUUC-Mmr-060878	Microcebus murinus	97.24	9.00e-127	445.00
IUUC-Mdo-062454	Monodelphis domestica	98.62	7.00e-128	448.00
IUUC-Mmu-063913	Mus musculus	96.77	2.00e-126	444.00
IUUC-Mpu-066125	Mustela putorius furo	97.24	9.00e-127	445.00
IUUC-Mlu-068007	Myotis lucifugus	97.24	9.00e-127	445.00
IUUC-Nle-069101	Nomascus leucogenys	97.24	9.00e-127	445.00
IUUC-Opr-071075	Ochotona princeps	97.24	9.00e-127	445.00
IUUC-Ont-072253	Oreochromis niloticus	92.17	1.00e-120	424.00
IUUC-Ocu-074583	Oryctolagus cuniculus	97.24	9.00e-127	445.00
IUUC-Ola-086586	Oryzias latipes	94.87	2.00e-85	308.00
IUUC-Oga-089047	Otolemur garnettii	97.24	9.00e-127	445.00
IUUC-Oar-089904	Ovis aries	90.37	3.00e-116	410.00
IUUC-Ptr-090678	Pan troglodytes	97.24	9.00e-127	445.00
IUUC-Pan-092090	Papio anubis	97.24	9.00e-127	445.00
IUUC-Pma-094650	Petromyzon marinus	84.33	2.00e-110	391.00
IUUC-Pfo-096131	Poecilia formosa	94.93	2.00e-124	437.00
IUUC-Pab-098709	Pongo abelii	97.24	9.00e-127	445.00
IUUC-Pca-100581	Procavia capensis	95.81	1.00e-110	391.00
IUUC-Pva-103066	Pteropus vampyrus	97.24	9.00e-127	445.00
IUUC-Rno-105224	Rattus norvegicus	97.24	9.00e-127	445.00
IUUC-Sce-106302	Saccharomyces cerevisiae	53.70	7.00e-16	77.00
IUUC-Sha-107247	Sarcophilus harrisii	98.95	7.00e-113	398.00
IUUC-Sar-113277	Sorex araneus	81.57	6.00e-101	359.00
IUUC-Ssc-115478	Sus scrofa	97.24	9.00e-127	445.00
IUUC-Tgu-117479	Taeniopygia guttata	98.16	6.00e-127	445.00
IUUC-Tru-118451	Takifugu rubripes	86.03	6.00e-108	382.00
IUUC-Tsy-119029	Tarsius syrichta	92.50	1.00e-82	297.00
IUUC-Tbe-128097	Tupaia belangeri	96.77	8.00e-126	442.00
IUUC-Ttr-128871	Tursiops truncatus	98.72	3.00e-89	319.00
IUUC-Vpa-130754	Vicugna pacos	97.24	9.00e-127	445.00
IUUC-Xtr-132275	Xenopus tropicalis	91.70	2.00e-123	433.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence