iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059272

Ensembl Protein ID

ENSMGAP00000013880.2

UniProt Accession

G1NKE3; G1NKE3_MELGA

Protein Name

Uncharacterized protein

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000013151.2	ENSMGAT00000014799.2	ENSMGAP00000013880.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.80e-09	37.4	705	749

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ +s   ++p+ e wiC+ Cr
   Q: 705  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPS-LMSFPSGE-WICTFCR 749
           79*********....*******************.*******8.******8 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FSPPVGVIRC PICGQECAER HIIDNFFVKD TTEVPSSTVE KSNQVCTSCE DNAEAHGFCV 60
ECVEWLCKTC IRAHQRVKFT KDHTVRQKEE VSPEAVGVTS QRPVFCPFHK KEQLKLYCET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTCCCCTC CAGTTGGTGT TATCCGCTGT CCAATTTGTG GTCAGGAATG CGCAGAGAGA 60
CACATCATAG ATAACTTTTT TGTGAAGGAT ACCACAGAGG TTCCTAGTAG CACAGTAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	80.79	0.00e+00	1324.00
IUUC-Apl-003697	Anas platyrhynchos	93.76	0.00e+00	1553.00
IUUC-Bta-013282	Bos taurus	80.11	0.00e+00	1321.00
IUUC-Cja-018920	Callithrix jacchus	78.96	0.00e+00	1342.00
IUUC-Cfa-020984	Canis familiaris	80.26	0.00e+00	1331.00
IUUC-Cpo-022035	Cavia porcellus	79.53	0.00e+00	1375.00
IUUC-Csa-024208	Chlorocebus sabaeus	80.47	0.00e+00	1348.00
IUUC-Cin-025200	Ciona intestinalis	44.67	2.00e-44	174.00
IUUC-Dno-029145	Dasypus novemcinctus	80.79	0.00e+00	1385.00
IUUC-Dor-030396	Dipodomys ordii	77.14	0.00e+00	1004.00
IUUC-Ete-032414	Echinops telfairi	75.20	0.00e+00	777.00
IUUC-Eca-033489	Equus caballus	80.92	0.00e+00	1333.00
IUUC-Eeu-034654	Erinaceus europaeus	74.07	3.00e-172	598.00
IUUC-Fca-035844	Felis catus	77.59	0.00e+00	1219.00
IUUC-Fal-036735	Ficedula albicollis	89.50	0.00e+00	1519.00
IUUC-Gga-041124	Gallus gallus	98.16	0.00e+00	1621.00
IUUC-Ggo-044542	Gorilla gorilla	80.47	0.00e+00	1348.00
IUUC-Hsa-046785	Homo sapiens	80.36	0.00e+00	1345.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	80.47	0.00e+00	1329.00
IUUC-Laf-054279	Loxodonta africana	79.04	0.00e+00	1328.00
IUUC-Mcc-055668	Macaca mulatta	80.47	0.00e+00	1348.00
IUUC-Meu-056195	Macropus eugenii	68.70	0.00e+00	719.00
IUUC-Mmr-060936	Microcebus murinus	80.04	0.00e+00	1330.00
IUUC-Mdo-062848	Monodelphis domestica	80.85	0.00e+00	1358.00
IUUC-Mmu-063598	Mus musculus	79.42	0.00e+00	1299.00
IUUC-Mpu-066272	Mustela putorius furo	80.04	0.00e+00	1319.00
IUUC-Mlu-067958	Myotis lucifugus	78.93	0.00e+00	1328.00
IUUC-Nle-069375	Nomascus leucogenys	80.47	0.00e+00	1348.00
IUUC-Oan-073393	Ornithorhynchus anatinus	76.32	0.00e+00	927.00
IUUC-Ocu-074873	Oryctolagus cuniculus	77.83	0.00e+00	1332.00
IUUC-Oga-088692	Otolemur garnettii	79.83	0.00e+00	1298.00
IUUC-Oar-090160	Ovis aries	80.60	0.00e+00	1326.00
IUUC-Ptr-090756	Pan troglodytes	80.36	0.00e+00	1345.00
IUUC-Pan-091719	Papio anubis	80.36	0.00e+00	1344.00
IUUC-Psi-093433	Pelodiscus sinensis	85.70	0.00e+00	1449.00
IUUC-Pab-098599	Pongo abelii	79.19	0.00e+00	1317.00
IUUC-Pca-100540	Procavia capensis	75.71	0.00e+00	816.00
IUUC-Pva-102478	Pteropus vampyrus	74.49	0.00e+00	1171.00
IUUC-Sha-106740	Sarcophilus harrisii	76.77	0.00e+00	1278.00
IUUC-Sar-113615	Sorex araneus	78.62	0.00e+00	1142.00
IUUC-Tgu-117368	Taeniopygia guttata	88.86	0.00e+00	1506.00
IUUC-Tsy-118904	Tarsius syrichta	78.53	0.00e+00	1339.00
IUUC-Tbe-127354	Tupaia belangeri	63.97	3.00e-156	545.00
IUUC-Ttr-128983	Tursiops truncatus	75.86	0.00e+00	961.00
IUUC-Vpa-130420	Vicugna pacos	78.00	0.00e+00	1297.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence