iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106716

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01178527

Gene Name

KLHL6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000013161.1	ENSSHAT00000015566.1	ENSSHAP00000015439.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-08	35.3	67	111
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.10e-10	39.7	166	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik 46
           +Dv+l+v+ +ef++h++vLaa+S +F+  fl + ++   +++  ik
   Q: 67   TDVVLCVDVQEFSCHRAVLAAASNYFRYIFLRKDRKIY-EKRLLIK 111
           7*****************************87766653.4444444 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +eNc+gilr+Ad++++++Lk++++ +i+++F+
   Q: 166  PENCVGILRLADTHSLDHLKKQVQGYIIQNFT 197
           89*****************************7 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

HGAPRNMGDT VEKSLEGPLT PLDEGHARKR GDLVEVLNGE KVKFDDTELS RILQNGLENL 60
RLENSLTDVV LCVDVQEFSC HRAVLAAASN YFRYIFLRKD RKIYEKRLLI KGVLIHPIHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGGTGCCC CCCGAAACAT GGGGGACACT GTGGAGAAAA GTCTGGAGGG CCCCCTCACC 60
CCTCTGGACG AGGGCCACGC CAGGAAGAGG GGAGATCTGG TGGAGGTCCT GAATGGCGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR029851--KLHL6
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0050853--P:B cell receptor signaling pathway
GO:0002467--P:germinal center formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001509	Ailuropoda melanoleuca	84.59	0.00e+00	1078.00
IUUC-Apl-003490	Anas platyrhynchos	80.00	0.00e+00	1026.00
IUUC-Aca-005136	Anolis carolinensis	77.80	0.00e+00	971.00
IUUC-Ame-010886	Astyanax mexicanus	63.15	0.00e+00	752.00
IUUC-Bta-013473	Bos taurus	84.10	0.00e+00	1041.00
IUUC-Cja-018888	Callithrix jacchus	83.61	0.00e+00	1067.00
IUUC-Cpo-021761	Cavia porcellus	81.48	0.00e+00	1019.00
IUUC-Csa-023206	Chlorocebus sabaeus	83.80	0.00e+00	1072.00
IUUC-Cin-025367	Ciona intestinalis	37.36	1.00e-115	409.00
IUUC-Csv-026076	Ciona savignyi	37.52	1.00e-107	383.00
IUUC-Dre-027948	Danio rerio	67.30	0.00e+00	823.00
IUUC-Dno-030045	Dasypus novemcinctus	84.10	0.00e+00	1069.00
IUUC-Dor-030839	Dipodomys ordii	77.54	0.00e+00	965.00
IUUC-Eca-033608	Equus caballus	83.93	0.00e+00	1046.00
IUUC-Eeu-034640	Erinaceus europaeus	82.62	0.00e+00	1058.00
IUUC-Fca-036065	Felis catus	83.60	0.00e+00	1076.00
IUUC-Fal-036949	Ficedula albicollis	79.33	0.00e+00	999.00
IUUC-Gmo-039661	Gadus morhua	53.42	4.00e-154	537.00
IUUC-Gga-040740	Gallus gallus	79.34	0.00e+00	1018.00
IUUC-Gac-042413	Gasterosteus aculeatus	57.40	0.00e+00	707.00
IUUC-Ggo-045167	Gorilla gorilla	83.63	0.00e+00	1070.00
IUUC-Hsa-046120	Homo sapiens	83.63	0.00e+00	1070.00
IUUC-Itr-047926	Ictidomys tridecemlineatus	83.96	0.00e+00	1071.00
IUUC-Lch-049709	Latimeria chalumnae	74.27	0.00e+00	958.00
IUUC-Loc-052239	Lepisosteus oculatus	72.13	0.00e+00	889.00
IUUC-Laf-054511	Loxodonta africana	83.77	0.00e+00	1071.00
IUUC-Mcc-055109	Macaca mulatta	83.80	0.00e+00	1073.00
IUUC-Meu-056522	Macropus eugenii	77.31	5.00e-106	378.00
IUUC-Mga-060012	Meleagris gallopavo	77.72	0.00e+00	994.00
IUUC-Mmr-061364	Microcebus murinus	83.61	0.00e+00	1064.00
IUUC-Mdo-063033	Monodelphis domestica	82.47	0.00e+00	1016.00
IUUC-Mmu-063880	Mus musculus	82.32	0.00e+00	1032.00
IUUC-Mlu-068233	Myotis lucifugus	83.63	0.00e+00	1051.00
IUUC-Opr-070638	Ochotona princeps	80.23	0.00e+00	734.00
IUUC-Ont-071960	Oreochromis niloticus	56.14	0.00e+00	703.00
IUUC-Oan-073406	Ornithorhynchus anatinus	83.28	0.00e+00	1056.00
IUUC-Ocu-074612	Oryctolagus cuniculus	83.09	0.00e+00	1065.00
IUUC-Ola-087181	Oryzias latipes	54.90	0.00e+00	690.00
IUUC-Oga-088955	Otolemur garnettii	83.61	0.00e+00	1066.00
IUUC-Oar-089682	Ovis aries	83.93	0.00e+00	1040.00
IUUC-Ptr-090969	Pan troglodytes	83.63	0.00e+00	1070.00
IUUC-Pan-092289	Papio anubis	83.80	0.00e+00	1072.00
IUUC-Psi-093279	Pelodiscus sinensis	80.20	0.00e+00	1035.00
IUUC-Pab-097957	Pongo abelii	83.33	0.00e+00	798.00
IUUC-Pca-100619	Procavia capensis	80.84	0.00e+00	1050.00
IUUC-Pva-102533	Pteropus vampyrus	78.76	2.00e-170	592.00
IUUC-Rno-106111	Rattus norvegicus	82.49	0.00e+00	1058.00
IUUC-Tgu-116839	Taeniopygia guttata	79.34	0.00e+00	1019.00
IUUC-Tru-117792	Takifugu rubripes	55.35	0.00e+00	683.00
IUUC-Tsy-119609	Tarsius syrichta	73.97	5.00e-124	437.00
IUUC-Tni-119682	Tetraodon nigroviridis	54.53	0.00e+00	676.00
IUUC-Tbe-127961	Tupaia belangeri	78.52	0.00e+00	964.00
IUUC-Ttr-128917	Tursiops truncatus	82.75	0.00e+00	874.00
IUUC-Vpa-130721	Vicugna pacos	84.12	0.00e+00	735.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence