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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046448
Ensembl Protein ID ENSP00000378286.3
UniProt Accession Q9H5J0; ZBTB3_HUMAN
Genbank Protein ID BAB15636.1; AAH25249.1
Protein Name Zinc finger and BTB domain-containing protein 3
Genbank Nucleotide ID AK027045; BC025249
Gene Name ZBTB3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000185670.7 ENST00000394807.3 ENSP00000378286.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACTargetScanRepTar
SomamiRmiRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMHPRD
Phospho.ELMUniProt
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 3.60e-12 48.1 74 140
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgklde 67
           +D+++ vg ++f ah++vLa++S++F+ lf++e e  k ++ v i+ + v + +f  ll+F+Y g+l++
   Q: 74   CDCTVMVGSTQFLAHRAVLASCSPFFQ-LFYKERELDK-RDLVCIHnEiVTAPAFGLLLDFMYAGQLTL 140
           8*************************6.9999999666.8999999559*****************975 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MLREFSKWGV EASPGKAWER KRSLLRGAVG RYRGATGGDL FWAPFPSWGT MEFPEHSQQL 60
LQSLREQRSQ GFLCDCTVMV GSTQFLAHRA VLASCSPFFQ LFYKERELDK RDLVCIHNEI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046448|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATTAAAGCT GAGAAGGTGG GAAGGGGCGG AGCTCGCCCT GTGGCTGCTC GGTGGTGGGT 60
GAGGTATCAG CTTTCTCCGC TAGTTCCCAC CCTGGTAGTC CTTAGCCCCT GGAATGCGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046448|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2
Pfam

PF00651--BTB
SMART

SM00225--BTB
SM00355--ZnF_C2H2
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG hsa:79842
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001326 Ailuropoda melanoleuca 84.19 0.00e+00 641.00
IUUC-Ame-011902 Astyanax mexicanus 66.44 7.00e-43 168.00
IUUC-Bta-012507 Bos taurus 86.21 0.00e+00 769.00
IUUC-Cja-018748 Callithrix jacchus 93.21 0.00e+00 953.00
IUUC-Cfa-020906 Canis familiaris 82.49 0.00e+00 782.00
IUUC-Cpo-021696 Cavia porcellus 75.95 0.00e+00 687.00
IUUC-Csa-023629 Chlorocebus sabaeus 95.28 0.00e+00 1023.00
IUUC-Cho-024423 Choloepus hoffmanni 83.91 0.00e+00 719.00
IUUC-Dre-027796 Danio rerio 63.01 6.00e-48 185.00
IUUC-Dno-030069 Dasypus novemcinctus 82.99 0.00e+00 829.00
IUUC-Dor-031057 Dipodomys ordii 86.79 7.00e-120 424.00
IUUC-Ete-032854 Echinops telfairi 78.72 9.00e-114 402.00
IUUC-Fca-036206 Felis catus 86.30 0.00e+00 700.00
IUUC-Gac-042567 Gasterosteus aculeatus 42.03 1.00e-56 213.00
IUUC-Ggo-044670 Gorilla gorilla 99.65 0.00e+00 1070.00
IUUC-Itr-048590 Ictidomys tridecemlineatus 86.45 0.00e+00 748.00
IUUC-Lch-050267 Latimeria chalumnae 51.29 3.00e-119 422.00
IUUC-Mcc-055439 Macaca mulatta 95.28 0.00e+00 1025.00
IUUC-Meu-056567 Macropus eugenii 67.51 1.00e-146 513.00
IUUC-Mmr-061362 Microcebus murinus 89.13 0.00e+00 869.00
IUUC-Mmu-063316 Mus musculus 81.87 0.00e+00 721.00
IUUC-Mpu-066372 Mustela putorius furo 84.20 0.00e+00 687.00
IUUC-Mlu-067401 Myotis lucifugus 83.75 0.00e+00 722.00
IUUC-Nle-069925 Nomascus leucogenys 95.63 0.00e+00 1012.00
IUUC-Ont-071564 Oreochromis niloticus 42.64 5.00e-40 159.00
IUUC-Oan-072884 Ornithorhynchus anatinus 58.04 3.00e-63 235.00
IUUC-Ocu-074908 Oryctolagus cuniculus 88.07 0.00e+00 879.00
IUUC-Oga-088959 Otolemur garnettii 88.46 0.00e+00 894.00
IUUC-Oar-089276 Ovis aries 84.83 0.00e+00 778.00
IUUC-Ptr-091133 Pan troglodytes 99.65 0.00e+00 1067.00
IUUC-Pan-092425 Papio anubis 92.66 0.00e+00 1038.00
IUUC-Psi-093363 Pelodiscus sinensis 56.92 4.00e-129 454.00
IUUC-Pab-098448 Pongo abelii 98.08 0.00e+00 1051.00
IUUC-Pca-100254 Procavia capensis 80.61 5.00e-120 423.00
IUUC-Pva-102350 Pteropus vampyrus 85.13 6.00e-140 491.00
IUUC-Rno-105961 Rattus norvegicus 82.06 0.00e+00 705.00
IUUC-Sar-113623 Sorex araneus 80.05 3.00e-151 527.00
IUUC-Ssc-115854 Sus scrofa 80.63 0.00e+00 820.00
IUUC-Tru-118097 Takifugu rubripes 52.09 1.00e-42 167.00
IUUC-Tni-120671 Tetraodon nigroviridis 42.41 1.00e-41 164.00
Created Date 25-Jun-2017

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