iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013428

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02013531

Gene Name

RNF41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000026754.4	ENSBTAT00000038204.4	ENSBTAP00000038019.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-06	28.6	12	69
E3 activity/RING/RING	3.30e-06	27.6	18	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnl 59
           v e+++CpI   + ++Pv +p + + +  ++I +w++++++ cPv+r+ +t   l P  
   Q: 12   VDEDLICPICSGVLEEPVQAPhCEHAFCNACITQWFSQQQT-CPVDRSVVTVAHLRPVP 69
           56899******************************998887.******99998887764 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC   +++ p+  p C H+f+  C+ +w       s++++CP++r
   Q: 18   CPICSGVLEE-PVQAPhCEHAFCNACITQW------FSQQQTCPVDR 57
           ****999999.777777*************......********987 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MGYDVTRFQG DVDEDLICPI CSGVLEEPVQ APHCEHAFCN ACITQWFSQQ QTCPVDRSVV 60
TVAHLRPVPR IMRNMLSKLQ IACDNAVFGC SAIVRLDNLM SHLSDCEHNP KRPVTCEQGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCAGAAA AGGCTGGGAC CCGGCACCCG AGCTATCTCT CGGCCGCTGC GGGTACAGAG 60
AGTCCAGACC GCTTCCAGGG CGGTGCGTAC GGCGCCTGCG CGCGATCCCA CTTAAAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008974--TRAF-like
IPR015036--USP8_interacting
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF08941--USP8_interact

SMART

SM00184--RING

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0031386--F:protein tag
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0030336--P:negative regulation of cell migration
GO:0008285--P:negative regulation of cell proliferation
GO:1901525--P:negative regulation of macromitophagy
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0010498--P:proteasomal protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:2000114--P:regulation of establishment of cell polarity
GO:0045619--P:regulation of lymphocyte differentiation
GO:0043408--P:regulation of MAPK cascade
GO:0045637--P:regulation of myeloid cell differentiation
GO:0051896--P:regulation of protein kinase B signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002398	Ailuropoda melanoleuca	93.38	2.00e-178	617.00
IUUC-Apl-003568	Anas platyrhynchos	89.94	3.00e-170	590.00
IUUC-Aca-005119	Anolis carolinensis	90.54	6.00e-174	602.00
IUUC-Ame-010708	Astyanax mexicanus	86.12	1.00e-167	582.00
IUUC-Cja-019844	Callithrix jacchus	93.40	2.00e-177	614.00
IUUC-Cfa-021124	Canis familiaris	93.69	8.00e-179	619.00
IUUC-Cpo-022325	Cavia porcellus	93.38	2.00e-178	617.00
IUUC-Csa-023113	Chlorocebus sabaeus	93.69	8.00e-179	619.00
IUUC-Cho-024991	Choloepus hoffmanni	89.18	4.00e-102	363.00
IUUC-Cne-026870	Cryptococcus neoformans	37.70	7.00e-20	92.40
IUUC-Dre-028730	Danio rerio	85.80	3.00e-167	580.00
IUUC-Dno-028908	Dasypus novemcinctus	92.68	1.00e-159	555.00
IUUC-Dor-030411	Dipodomys ordii	94.01	6.00e-179	619.00
IUUC-Dse-031478	Dothistroma septosporum	29.13	4.00e-09	56.60
IUUC-Dme-031868	Drosophila melanogaster	57.59	6.00e-107	380.00
IUUC-Ete-032896	Echinops telfairi	81.13	4.00e-124	437.00
IUUC-Eca-034135	Equus caballus	93.69	8.00e-179	619.00
IUUC-Eeu-034675	Erinaceus europaeus	93.38	3.00e-178	617.00
IUUC-Fca-035612	Felis catus	93.69	8.00e-179	619.00
IUUC-Fal-037150	Ficedula albicollis	42.55	4.00e-29	121.00
IUUC-Gmo-039648	Gadus morhua	83.60	5.00e-162	563.00
IUUC-Gga-040474	Gallus gallus	90.85	2.00e-174	604.00
IUUC-Gac-041951	Gasterosteus aculeatus	84.54	3.00e-164	570.00
IUUC-Ggo-045126	Gorilla gorilla	93.40	2.00e-177	614.00
IUUC-Hsa-046402	Homo sapiens	93.69	8.00e-179	619.00
IUUC-Itr-047895	Ictidomys tridecemlineatus	93.69	8.00e-179	619.00
IUUC-Lch-050266	Latimeria chalumnae	88.01	3.00e-170	590.00
IUUC-Loc-052547	Lepisosteus oculatus	86.44	7.00e-168	582.00
IUUC-Laf-054332	Loxodonta africana	93.71	1.00e-177	615.00
IUUC-Mcc-055869	Macaca mulatta	93.69	8.00e-179	619.00
IUUC-Meu-056735	Macropus eugenii	93.03	5.00e-160	556.00
IUUC-Mla-059147	Melampsora laricipopulina	37.11	7.00e-13	68.20
IUUC-Mga-060100	Meleagris gallopavo	90.85	2.00e-174	604.00
IUUC-Mmr-061382	Microcebus murinus	93.69	8.00e-179	619.00
IUUC-Mmu-064225	Mus musculus	94.01	4.00e-179	620.00
IUUC-Mpu-066709	Mustela putorius furo	93.69	8.00e-179	619.00
IUUC-Mlu-067168	Myotis lucifugus	93.38	1.00e-178	618.00
IUUC-Nle-070176	Nomascus leucogenys	93.69	8.00e-179	619.00
IUUC-Opr-070259	Ochotona princeps	93.38	1.00e-178	618.00
IUUC-Ont-071235	Oreochromis niloticus	85.49	3.00e-166	577.00
IUUC-Oan-072850	Ornithorhynchus anatinus	95.45	1.00e-83	303.00
IUUC-Ocu-074165	Oryctolagus cuniculus	93.38	1.00e-178	618.00
IUUC-Ola-086658	Oryzias latipes	83.91	2.00e-162	564.00
IUUC-Oga-088933	Otolemur garnettii	93.69	8.00e-179	619.00
IUUC-Oar-090089	Ovis aries	94.01	6.00e-179	619.00
IUUC-Ptr-091263	Pan troglodytes	93.69	8.00e-179	619.00
IUUC-Pan-092926	Papio anubis	93.69	8.00e-179	619.00
IUUC-Psi-093934	Pelodiscus sinensis	83.33	6.00e-156	543.00
IUUC-Pma-094578	Petromyzon marinus	65.52	2.00e-117	415.00
IUUC-Pfo-097431	Poecilia formosa	85.49	8.00e-166	575.00
IUUC-Pab-097852	Pongo abelii	93.69	8.00e-179	619.00
IUUC-Pca-100496	Procavia capensis	85.22	2.00e-156	545.00
IUUC-Pva-103157	Pteropus vampyrus	90.00	1.00e-104	372.00
IUUC-Pgr-103569	Puccinia graminis	37.74	3.00e-13	69.30
IUUC-Pyt-104429	Pyrenophora triticirepentis	36.70	2.00e-12	67.40
IUUC-Rno-105928	Rattus norvegicus	93.38	3.00e-178	617.00
IUUC-Sha-107556	Sarcophilus harrisii	93.08	6.00e-177	612.00
IUUC-Sar-113208	Sorex araneus	93.69	8.00e-179	619.00
IUUC-Ssc-116011	Sus scrofa	94.01	6.00e-179	619.00
IUUC-Tgu-116882	Taeniopygia guttata	65.50	4.00e-61	227.00
IUUC-Tru-117987	Takifugu rubripes	85.17	2.00e-165	574.00
IUUC-Tsy-118785	Tarsius syrichta	93.38	6.00e-177	612.00
IUUC-Tni-120165	Tetraodon nigroviridis	84.86	4.00e-165	573.00
IUUC-Tbe-127920	Tupaia belangeri	90.50	9.00e-107	379.00
IUUC-Ttr-129160	Tursiops truncatus	93.69	2.00e-178	617.00
IUUC-Vpa-130629	Vicugna pacos	93.69	8.00e-179	619.00
IUUC-Xtr-131895	Xenopus tropicalis	91.80	5.00e-175	606.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence