iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000001219.3	ENSSSCT00000035675.1	ENSSSCP00000028411.1
ENSSSCG00000001219.3	ENSSSCT00000001317.2	ENSSSCP00000001288.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.41	0.00e+00	983.00	IUUC-Hsa-046029
E3 activity/RING/RING	99.22	0.00e+00	982.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

TRVGLARAGR GYPVSVAPRG HRLPRLPAPE APRPVSPRAA GKASQVLGGE NCPALSPGGA 60
ALRQPGSPPR AAPKQRTGGK SRRVGLLAGL GSRAHARAPP RARAMASGSV AECLQQETTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCGGGTGG GCCTGGCGCG TGCAGGCAGG GGCTACCCTG TCTCCGTCGC GCCCCGCGGA 60
CACCGCCTGC CTCGGTTACC TGCTCCTGAG GCTCCCCGCC CGGTCAGCCC CAGGGCAGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR020457--Znf_B-box_chordata
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01406--BBOXZNFINGER
PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	98.62	0.00e+00	975.00
IUUC-Apl-003609	Anas platyrhynchos	40.21	2.00e-96	346.00
IUUC-Bta-013520	Bos taurus	100.00	0.00e+00	992.00
IUUC-Cja-019557	Callithrix jacchus	97.66	0.00e+00	969.00
IUUC-Cfa-020583	Canis familiaris	89.45	0.00e+00	926.00
IUUC-Cpo-021738	Cavia porcellus	90.64	0.00e+00	882.00
IUUC-Csa-023502	Chlorocebus sabaeus	99.42	0.00e+00	987.00
IUUC-Cho-024563	Choloepus hoffmanni	96.40	0.00e+00	626.00
IUUC-Dno-029747	Dasypus novemcinctus	96.39	0.00e+00	910.00
IUUC-Dor-030243	Dipodomys ordii	96.69	0.00e+00	937.00
IUUC-Ete-032749	Echinops telfairi	84.34	0.00e+00	796.00
IUUC-Eca-034246	Equus caballus	99.20	0.00e+00	694.00
IUUC-Eeu-034481	Erinaceus europaeus	88.69	0.00e+00	870.00
IUUC-Fca-036152	Felis catus	98.66	0.00e+00	691.00
IUUC-Gac-042288	Gasterosteus aculeatus	36.07	2.00e-75	276.00
IUUC-Ggo-044987	Gorilla gorilla	89.31	0.00e+00	887.00
IUUC-Hsa-046029	Homo sapiens	99.42	0.00e+00	987.00
IUUC-Hvu-047784	Hordeum vulgare	30.38	1.00e-05	45.10
IUUC-Itr-048438	Ictidomys tridecemlineatus	99.61	0.00e+00	964.00
IUUC-Laf-054488	Loxodonta africana	96.89	0.00e+00	987.00
IUUC-Mcc-055352	Macaca mulatta	99.42	0.00e+00	987.00
IUUC-Mmr-060883	Microcebus murinus	99.42	0.00e+00	986.00
IUUC-Mmu-064242	Mus musculus	99.22	0.00e+00	986.00
IUUC-Mpu-065958	Mustela putorius furo	99.03	0.00e+00	991.00
IUUC-Mlu-068005	Myotis lucifugus	85.29	0.00e+00	654.00
IUUC-Nle-069710	Nomascus leucogenys	98.87	0.00e+00	642.00
IUUC-Opr-071200	Ochotona princeps	98.83	0.00e+00	976.00
IUUC-Ocu-074081	Oryctolagus cuniculus	98.02	0.00e+00	849.00
IUUC-Ola-087166	Oryzias latipes	33.94	6.00e-71	261.00
IUUC-Oga-088784	Otolemur garnettii	99.42	0.00e+00	988.00
IUUC-Oar-089433	Ovis aries	100.00	0.00e+00	992.00
IUUC-Ptr-090595	Pan troglodytes	99.42	0.00e+00	987.00
IUUC-Pan-092027	Papio anubis	99.42	0.00e+00	987.00
IUUC-Psi-093179	Pelodiscus sinensis	47.26	6.00e-116	410.00
IUUC-Pfo-096858	Poecilia formosa	33.96	9.00e-69	254.00
IUUC-Pab-098331	Pongo abelii	99.42	0.00e+00	987.00
IUUC-Pca-101091	Procavia capensis	99.61	0.00e+00	988.00
IUUC-Pva-103141	Pteropus vampyrus	99.22	0.00e+00	716.00
IUUC-Rno-105507	Rattus norvegicus	98.83	0.00e+00	981.00
IUUC-Sar-113713	Sorex araneus	90.23	0.00e+00	899.00
IUUC-Tru-118630	Takifugu rubripes	34.64	8.00e-73	267.00
IUUC-Tsy-119235	Tarsius syrichta	98.96	0.00e+00	703.00
IUUC-Tni-120295	Tetraodon nigroviridis	37.78	1.00e-75	276.00
IUUC-Tbe-127796	Tupaia belangeri	88.64	2.00e-139	488.00
IUUC-Ttr-128738	Tursiops truncatus	99.73	0.00e+00	696.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence