iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001945

Ensembl Protein ID

ENSAMEP00000018018.1

UniProt Accession

G1MF89; G1MF89_AILME

Genbank Protein ID

ENSAMEP00000018018

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ACTA01076420

Gene Name

ING1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000017057.1	ENSAMET00000018749.1	ENSAMEP00000018018.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.20e-09	36.3	211	258

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 211  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 258
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MLSPANGEQI HLVNYVEDYL DSIESLPFDL QRNVSLMREI DAKYQEILKE LDEYYEKFKR 60
ETDGVQKRRV LHCIQRALIR SQELGDEKIQ IVSQMVELVE NRTRQVDSHV ELFEAHQEVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGAGCC CTGCCAACGG GGAGCAGATC CACCTGGTGA ACTATGTGGA GGACTACCTG 60
GACTCCATTG AGTCTCTGCC TTTCGACCTG CAGAGAAACG TCTCGCTGAT GCGGGAGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006606--P:protein import into nucleus
GO:0010941--P:regulation of cell death

KEGG

aml:100478246

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003910	Anas platyrhynchos	93.88	2.00e-128	451.00
IUUC-Aca-004874	Anolis carolinensis	92.86	3.00e-126	444.00
IUUC-Ame-011262	Astyanax mexicanus	67.59	6.00e-97	347.00
IUUC-Bta-013507	Bos taurus	91.45	1.00e-93	335.00
IUUC-Cja-018925	Callithrix jacchus	90.68	3.00e-125	440.00
IUUC-Cfa-020947	Canis familiaris	99.28	1.00e-135	475.00
IUUC-Cpo-022286	Cavia porcellus	92.37	4.00e-102	364.00
IUUC-Csa-023825	Chlorocebus sabaeus	90.32	9.00e-125	439.00
IUUC-Cho-024577	Choloepus hoffmanni	95.28	2.00e-103	368.00
IUUC-Cne-027005	Cryptococcus neoformans	45.95	3.00e-16	79.30
IUUC-Dno-029834	Dasypus novemcinctus	96.06	1.00e-132	465.00
IUUC-Dor-030315	Dipodomys ordii	90.17	2.00e-103	369.00
IUUC-Ete-032408	Echinops telfairi	92.34	2.00e-98	352.00
IUUC-Eca-034244	Equus caballus	97.01	7.00e-106	376.00
IUUC-Fca-035391	Felis catus	94.59	2.00e-116	410.00
IUUC-Fal-036838	Ficedula albicollis	92.83	7.00e-128	449.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.90
IUUC-Gga-040619	Gallus gallus	93.19	6.00e-128	449.00
IUUC-Gac-041996	Gasterosteus aculeatus	64.54	2.00e-92	331.00
IUUC-Ggo-045481	Gorilla gorilla	87.71	9.00e-98	350.00
IUUC-Hsa-046170	Homo sapiens	87.71	8.00e-98	350.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	96.58	2.00e-106	377.00
IUUC-Lch-050397	Latimeria chalumnae	89.61	4.00e-124	437.00
IUUC-Loc-052038	Lepisosteus oculatus	82.17	4.00e-101	360.00
IUUC-Laf-054126	Loxodonta africana	96.06	7.00e-133	466.00
IUUC-Mcc-055031	Macaca mulatta	88.09	3.00e-97	348.00
IUUC-Meu-056248	Macropus eugenii	93.28	7.00e-103	366.00
IUUC-Mga-059217	Meleagris gallopavo	92.27	5.00e-100	357.00
IUUC-Mmr-061581	Microcebus murinus	95.06	2.00e-109	388.00
IUUC-Mdo-062452	Monodelphis domestica	95.70	6.00e-131	459.00
IUUC-Mmu-063412	Mus musculus	94.98	5.00e-131	459.00
IUUC-Mpu-066479	Mustela putorius furo	100.00	7.00e-110	390.00
IUUC-Mlu-067586	Myotis lucifugus	83.63	6.00e-120	423.00
IUUC-Nle-069122	Nomascus leucogenys	89.96	4.00e-124	436.00
IUUC-Opr-070835	Ochotona princeps	86.70	4.00e-86	310.00
IUUC-Oan-073023	Ornithorhynchus anatinus	92.11	3.00e-125	441.00
IUUC-Ocu-073779	Oryctolagus cuniculus	89.58	3.00e-96	344.00
IUUC-Ola-086891	Oryzias latipes	66.43	2.00e-92	332.00
IUUC-Oga-087954	Otolemur garnettii	94.98	3.00e-131	461.00
IUUC-Oar-090006	Ovis aries	93.19	9.00e-127	446.00
IUUC-Ptr-090589	Pan troglodytes	90.32	8.00e-125	439.00
IUUC-Pan-091896	Papio anubis	88.09	1.00e-97	349.00
IUUC-Psi-093266	Pelodiscus sinensis	94.62	3.00e-130	457.00
IUUC-Pma-094265	Petromyzon marinus	75.34	9.00e-34	135.00
IUUC-Pfo-097531	Poecilia formosa	61.36	2.00e-89	322.00
IUUC-Pab-098253	Pongo abelii	90.32	2.00e-124	438.00
IUUC-Pva-102753	Pteropus vampyrus	86.87	2.00e-95	342.00
IUUC-Rno-105964	Rattus norvegicus	93.16	4.00e-92	330.00
IUUC-Sha-107270	Sarcophilus harrisii	94.98	2.00e-129	454.00
IUUC-Tgu-116822	Taeniopygia guttata	93.19	4.00e-128	450.00
IUUC-Tni-119980	Tetraodon nigroviridis	57.52	6.00e-81	293.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	90.90
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.80
IUUC-Ttr-128672	Tursiops truncatus	95.32	5.00e-104	370.00
IUUC-Xtr-132200	Xenopus tropicalis	85.66	2.00e-115	408.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence