iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053699

Ensembl Protein ID

ENSLAFP00000000213.3

UniProt Accession

G3SLD2; G3SLD2_LOXAF

Protein Name

Uncharacterized protein

Gene Name

ATG16L2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000256.3	ENSLAFT00000000258.3	ENSLAFP00000000213.3
ENSLAFG00000000256.3	ENSLAFT00000026917.1	ENSLAFP00000018073.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-27	95.2	558	588
UBD/Beta-Prp	3.60e-46	158.1	337	622

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 8    claf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           ++ f +d  + ++Gs+Dg +++W+++tg+l+ 
   Q: 558  AV-FsPDrSYALAGSWDGALYIWNVDTGKLES 588
           33.599999*******************9875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           ++h s +++v+f p++sllatg++d+ i++w+v  g l   ++l+g  + +t+v+f+p+g+  + +   r++++w +   +   tl+gh
   Q: 337  DAHLSEVNAVCFGPNSSLLATGGADRLIRLWNVVGGRLeaNQTLEGAGGSITSVDFDPSGSQVLAATYNRAAQLWKVGETQSKETLSGH 425
           689999********************************88899******************999************************* PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +d+v++ +f  ++++ v+Gs+drt++ wdl   +c++ t ++   +  c  v + + +++sG++D+++r+Wd++   + +      +++
   Q: 426  TDKVTAAKFKLTRHHAVTGSRDRTVKEWDLGRAYCSR-TINV---LSYCHDVVCGDHIIISGHNDQKIRFWDSRGPHCTQVIP--VQGR 508
           ************************************9.4444...556777777677*************************5..589* PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgec.....vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
           v+sls+++++ +l+s+s+d t+k+ dl+ +++      + +++ +d++k   fsp+  + + gs Dg ++iW++++g+l ++l +++  
   Q: 509  VTSLSLSHDQLHLLSCSRDDTLKVIDLRVSNIrqvfrADGFKCGSDWTK-AVFSPDRSYALAGSWDGALYIWNVDTGKLESSLRGPHCA 596
           ****************************888833334444555556666.8899*********************************77 PP
   S: 267  visvavlsfgdnvlvlgsedskvniw 292
            +   +++++++++v++++  kv +w
   Q: 597  AVNAVAWCYSGSHVVSVDQGRKVVLW 622
           7777778************99*9999 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAGPSTPIVP DAPVAPWKRH IVLQLRQRDR TQKALFLELM PAYNRLLEKA ELLAQFSEKL 60
QPEPSDVTPT THQGWGKEES QALNQTKFPS PATLRVKCRR RKEGLLVCGE MAYQVVEKSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGGGC CCTCAACCCC CATCGTCCCG GATGCCCCCG TCGCGCCGTG GAAGCGCCAC 60
ATTGTGCTGC AGCTGCGGCA GCGGGATCGC ACGCAAAAGG CCCTCTTCCT GGAGCTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR013923--Autophagy-rel_prot_16
IPR020472--G-protein_beta_WD-40_rep
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08614--ATG16
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0039689--P:negative stranded viral RNA replication

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001470	Ailuropoda melanoleuca	67.50	0.00e+00	733.00
IUUC-Ame-011152	Astyanax mexicanus	41.96	9.00e-115	407.00
IUUC-Bta-013118	Bos taurus	84.32	0.00e+00	926.00
IUUC-Cja-020002	Callithrix jacchus	83.60	0.00e+00	908.00
IUUC-Cfa-020878	Canis familiaris	81.68	0.00e+00	900.00
IUUC-Cpo-022476	Cavia porcellus	81.72	0.00e+00	880.00
IUUC-Csa-024134	Chlorocebus sabaeus	84.37	0.00e+00	932.00
IUUC-Cho-024853	Choloepus hoffmanni	72.18	0.00e+00	627.00
IUUC-Dre-027949	Danio rerio	42.79	4.00e-129	454.00
IUUC-Dno-029683	Dasypus novemcinctus	85.91	0.00e+00	768.00
IUUC-Dor-030897	Dipodomys ordii	78.14	0.00e+00	927.00
IUUC-Ete-032957	Echinops telfairi	94.02	1.00e-132	466.00
IUUC-Eca-033303	Equus caballus	93.21	9.00e-170	588.00
IUUC-Eeu-035336	Erinaceus europaeus	73.45	6.00e-153	534.00
IUUC-Fca-036232	Felis catus	84.55	0.00e+00	977.00
IUUC-Gmo-038880	Gadus morhua	50.70	4.00e-70	259.00
IUUC-Ggo-045130	Gorilla gorilla	93.05	0.00e+00	704.00
IUUC-Hsa-046359	Homo sapiens	87.52	0.00e+00	903.00
IUUC-Itr-048780	Ictidomys tridecemlineatus	82.52	0.00e+00	926.00
IUUC-Lch-050669	Latimeria chalumnae	55.12	1.00e-96	346.00
IUUC-Loc-052789	Lepisosteus oculatus	43.27	4.00e-117	415.00
IUUC-Mcc-055657	Macaca mulatta	79.20	0.00e+00	824.00
IUUC-Meu-056639	Macropus eugenii	51.37	2.00e-114	405.00
IUUC-Mmr-061314	Microcebus murinus	78.31	0.00e+00	835.00
IUUC-Mdo-061841	Monodelphis domestica	65.40	0.00e+00	703.00
IUUC-Mmu-064065	Mus musculus	82.13	0.00e+00	944.00
IUUC-Mpu-066742	Mustela putorius furo	83.81	0.00e+00	897.00
IUUC-Mlu-067019	Myotis lucifugus	88.83	0.00e+00	685.00
IUUC-Nle-069037	Nomascus leucogenys	87.36	0.00e+00	946.00
IUUC-Opr-071039	Ochotona princeps	80.13	0.00e+00	881.00
IUUC-Oan-073431	Ornithorhynchus anatinus	72.53	7.00e-140	489.00
IUUC-Ocu-074772	Oryctolagus cuniculus	83.45	0.00e+00	839.00
IUUC-Ola-086964	Oryzias latipes	52.96	4.00e-83	301.00
IUUC-Oga-088188	Otolemur garnettii	84.14	0.00e+00	874.00
IUUC-Oar-090231	Ovis aries	77.99	0.00e+00	899.00
IUUC-Ptr-091434	Pan troglodytes	84.89	0.00e+00	858.00
IUUC-Pan-091868	Papio anubis	84.96	0.00e+00	915.00
IUUC-Psi-093652	Pelodiscus sinensis	64.04	2.00e-163	568.00
IUUC-Pfo-096960	Poecilia formosa	42.41	4.00e-101	362.00
IUUC-Pab-097776	Pongo abelii	86.70	0.00e+00	870.00
IUUC-Pca-100220	Procavia capensis	69.87	0.00e+00	662.00
IUUC-Ppe-101790	Prunus persica	31.78	1.00e-44	174.00
IUUC-Pva-103135	Pteropus vampyrus	86.61	0.00e+00	873.00
IUUC-Rno-105529	Rattus norvegicus	80.67	0.00e+00	967.00
IUUC-Sha-107062	Sarcophilus harrisii	65.18	0.00e+00	732.00
IUUC-Sar-113109	Sorex araneus	68.23	2.00e-135	475.00
IUUC-Sbi-114819	Sorghum bicolor	33.10	1.00e-36	147.00
IUUC-Ssc-115271	Sus scrofa	83.97	0.00e+00	907.00
IUUC-Ttr-128267	Tursiops truncatus	80.13	0.00e+00	878.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence