iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117034

Ensembl Protein ID

ENSTGUP00000006752.1

UniProt Accession

H0Z849; H0Z849_TAEGU

Genbank Protein ID

ENSTGUP00000006752

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ABQF01011387

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000006578.1	ENSTGUT00000006820.1	ENSTGUP00000006752.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.80e-09	35.6	158	204

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 158  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVGLT---YKPKGK-WYCPKCR 204
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

FIEALKEIDD VYEKYKSEND PVQKKRLQQH LQRALINSQE LGDEKIQIVT QMLELVENRA 60
RQMETHSQCF QDLSENEKPL EKAKMESCQP ERSSRRPRRQ RTSESRDLCH IANGIDDCDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTATAGAAG CGTTAAAAGA AATAGATGAT GTCTATGAAA AATACAAGTC AGAAAACGAT 60
CCTGTTCAGA AGAAACGCTT GCAGCAGCAC CTTCAGCGTG CATTAATCAA CAGTCAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	90.64	2.00e-82	298.00
IUUC-Apl-003705	Anas platyrhynchos	99.11	6.00e-104	369.00
IUUC-Aca-004990	Anolis carolinensis	89.24	3.00e-91	328.00
IUUC-Bta-012721	Bos taurus	89.66	1.00e-81	295.00
IUUC-Cja-018960	Callithrix jacchus	88.95	2.00e-73	268.00
IUUC-Cfa-020869	Canis familiaris	90.15	9.00e-82	296.00
IUUC-Cpo-021414	Cavia porcellus	88.18	9.00e-80	289.00
IUUC-Csa-023304	Chlorocebus sabaeus	90.00	1.00e-74	272.00
IUUC-Dno-029945	Dasypus novemcinctus	90.64	3.00e-83	301.00
IUUC-Dor-030141	Dipodomys ordii	88.67	2.00e-78	285.00
IUUC-Ete-032709	Echinops telfairi	86.22	1.00e-88	318.00
IUUC-Eca-033432	Equus caballus	90.15	3.00e-81	294.00
IUUC-Eeu-035285	Erinaceus europaeus	91.13	2.00e-82	297.00
IUUC-Fca-036467	Felis catus	90.15	2.00e-81	294.00
IUUC-Fal-036700	Ficedula albicollis	99.11	1.00e-104	371.00
IUUC-Gga-040175	Gallus gallus	99.10	2.00e-103	367.00
IUUC-Hsa-045837	Homo sapiens	90.00	1.00e-74	272.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	89.66	3.00e-81	294.00
IUUC-Lch-049965	Latimeria chalumnae	83.56	2.00e-85	308.00
IUUC-Laf-053353	Loxodonta africana	87.56	4.00e-90	323.00
IUUC-Mcc-055155	Macaca mulatta	89.08	6.00e-65	239.00
IUUC-Meu-056470	Macropus eugenii	88.89	4.00e-90	323.00
IUUC-Mga-059570	Meleagris gallopavo	99.55	2.00e-103	367.00
IUUC-Mmr-061385	Microcebus murinus	89.47	3.00e-74	270.00
IUUC-Mdo-062144	Monodelphis domestica	89.33	2.00e-90	325.00
IUUC-Mmu-063215	Mus musculus	89.66	3.00e-81	294.00
IUUC-Mpu-065749	Mustela putorius furo	90.15	6.00e-82	296.00
IUUC-Mlu-067245	Myotis lucifugus	69.78	2.00e-73	268.00
IUUC-Nle-069968	Nomascus leucogenys	90.00	6.00e-74	269.00
IUUC-Ocu-074870	Oryctolagus cuniculus	90.64	2.00e-82	298.00
IUUC-Oga-088336	Otolemur garnettii	90.00	1.00e-74	272.00
IUUC-Oar-090136	Ovis aries	89.16	3.00e-81	294.00
IUUC-Ptr-091348	Pan troglodytes	90.00	3.00e-74	270.00
IUUC-Pan-092819	Papio anubis	90.00	1.00e-74	272.00
IUUC-Psi-093854	Pelodiscus sinensis	93.10	3.00e-68	250.00
IUUC-Pab-098346	Pongo abelii	90.53	3.00e-75	274.00
IUUC-Pca-100278	Procavia capensis	85.78	3.00e-88	317.00
IUUC-Pva-103190	Pteropus vampyrus	90.15	1.00e-81	295.00
IUUC-Rno-104940	Rattus norvegicus	88.18	3.00e-80	290.00
IUUC-Sha-107533	Sarcophilus harrisii	88.89	7.00e-90	323.00
IUUC-Sar-113630	Sorex araneus	89.66	7.00e-81	292.00
IUUC-Ssc-115734	Sus scrofa	90.15	1.00e-81	295.00
IUUC-Tsy-119494	Tarsius syrichta	89.47	1.00e-73	268.00
IUUC-Ttr-128442	Tursiops truncatus	89.66	5.00e-81	293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence