iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008080

Ensembl Protein ID

CADACLAP00000162

UniProt Accession

A1C4T2; A1C4T2_ASPCL

Genbank Protein ID

EAW14700.1

Protein Name

Ubiquitin conjugating enzyme (UbcH), putative

Genbank Nucleotide ID

DS027004

Gene Name

ACLA_001110

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00000166	CADACLAT00000166	CADACLAP00000162

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.10e-52	175.5	8	157

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk.ifhPnvyenGkvClsilk..... 87
           Rl +e+k+l+++ppegi+a+pv+e+d+++we+li Gpe+tpYeggvF +e++fp+dYP++PP++kf+   ++hPnvy+nG+vC+sil+     
   Q: 8    RLFHEYKNLSTNPPEGITAGPVSEDDMFHWEALIQGPEGTPYEGGVFAAELKFPKDYPLSPPTMKFVGGgVWHPNVYPNGTVCISILHppgdd 100
           8999***************************************************************999*****************888889 PP
   S: 88   ......eeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
                  +e+Wsp +sve++l+s++s+laepn esp+n+eaa++++++r+ey++kvr
   Q: 101  pnhyehASERWSPIQSVEKILISVMSMLAEPNDESPANVEAAKMWRERRSEYERKVR 157
           99999999***********************************************98 PP

Organism

Aspergillus clavatus

Protein Sequence
(Fasta)

MSTVAQKRLF HEYKNLSTNP PEGITAGPVS EDDMFHWEAL IQGPEGTPYE GGVFAAELKF 60
PKDYPLSPPT MKFVGGGVWH PNVYPNGTVC ISILHPPGDD PNHYEHASER WSPIQSVEKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGACCG TCGCGCAGAA ACGTCTCTTT CACGAGTACA AAAACCTCTC GACCAACCCT 60
CCCGAGGGGA TCACTGCAGG TCCAGTCAGC GAGGATGATA TGTTCCATTG GGAAGCCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0000837--C:Doa10p ubiquitin ligase complex
GO:0000839--C:Hrd1p ubiquitin ligase ERAD-L complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0006333--P:chromatin assembly or disassembly
GO:0030466--P:chromatin silencing at silent mating-type cassette
GO:0031505--P:fungal-type cell wall organization
GO:0010620--P:negative regulation of transcription by transcription factor catabolism
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

act:ACLA_001110

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000411	Aegilops tauschii	44.07	2.00e-37	147.00
IUUC-Aml-002172	Ailuropoda melanoleuca	63.29	4.00e-56	208.00
IUUC-Atr-003150	Amborella trichopoda	59.18	2.00e-39	152.00
IUUC-Apl-003761	Anas platyrhynchos	61.21	2.00e-56	209.00
IUUC-Aca-005062	Anolis carolinensis	62.65	6.00e-58	214.00
IUUC-Aly-005673	Arabidopsis lyrata	59.72	8.00e-44	167.00
IUUC-Ath-007644	Arabidopsis thaliana	59.72	8.00e-44	167.00
IUUC-Ago-007853	Ashbya gossypii	63.25	2.00e-62	229.00
IUUC-Afl-008478	Aspergillus flavus	96.39	2.00e-95	338.00
IUUC-Afu-009051	Aspergillus fumigatus	99.40	6.00e-97	343.00
IUUC-Ani-009271	Aspergillus nidulans	94.58	6.00e-82	294.00
IUUC-Ang-009748	Aspergillus niger	97.59	9.00e-96	340.00
IUUC-Aor-010228	Aspergillus oryzae	95.78	4.00e-95	337.00
IUUC-Ate-010293	Aspergillus terreus	96.99	2.00e-95	339.00
IUUC-Ame-011698	Astyanax mexicanus	66.27	8.00e-63	230.00
IUUC-Bgr-012226	Blumeria graminis	75.76	2.00e-73	265.00
IUUC-Bta-013324	Bos taurus	60.54	5.00e-47	178.00
IUUC-Bci-013676	Botrytis cinerea	80.00	5.00e-78	281.00
IUUC-Bdi-014838	Brachypodium distachyon	55.56	4.00e-46	175.00
IUUC-Bol-016017	Brassica oleracea	60.42	3.00e-49	185.00
IUUC-Bra-017324	Brassica rapa	56.38	1.00e-42	163.00
IUUC-Cel-018676	Caenorhabditis elegans	62.65	1.00e-60	223.00
IUUC-Cja-019767	Callithrix jacchus	62.05	6.00e-59	217.00
IUUC-Cfa-020047	Canis familiaris	63.25	7.00e-60	220.00
IUUC-Cpo-021507	Cavia porcellus	62.65	3.00e-59	218.00
IUUC-Cre-022895	Chlamydomonas reinhardtii	56.88	3.00e-46	175.00
IUUC-Csa-023745	Chlorocebus sabaeus	59.39	6.00e-56	207.00
IUUC-Cin-025310	Ciona intestinalis	63.25	1.00e-60	223.00
IUUC-Csv-025961	Ciona savignyi	62.65	1.00e-59	219.00
IUUC-Cgl-026553	Colletotrichum gloeosporioides	81.82	1.00e-79	286.00
IUUC-Cne-026903	Cryptococcus neoformans	62.65	2.00e-55	206.00
IUUC-Cme-027321	Cyanidioschyzon merolae	57.06	7.00e-48	181.00
IUUC-Dre-027900	Danio rerio	66.27	9.00e-63	230.00
IUUC-Dno-029688	Dasypus novemcinctus	62.34	9.00e-55	203.00
IUUC-Dor-030686	Dipodomys ordii	51.83	5.00e-43	165.00
IUUC-Dse-031253	Dothistroma septosporum	80.12	5.00e-79	284.00
IUUC-Dme-031849	Drosophila melanogaster	65.66	1.00e-61	226.00
IUUC-Ete-033010	Echinops telfairi	62.65	7.00e-58	214.00
IUUC-Eca-033294	Equus caballus	61.39	1.00e-55	206.00
IUUC-Fca-036442	Felis catus	63.04	7.00e-49	184.00
IUUC-Fal-037188	Ficedula albicollis	62.99	1.00e-55	206.00
IUUC-Fox-037762	Fusarium oxysporum	81.93	2.00e-80	289.00
IUUC-Fso-038181	Fusarium solani	80.72	1.00e-79	286.00
IUUC-Gmo-038663	Gadus morhua	63.86	2.00e-61	226.00
IUUC-Ggr-039808	Gaeumannomyces graminis	81.71	6.00e-80	287.00
IUUC-Gga-040355	Gallus gallus	63.25	7.00e-60	220.00
IUUC-Gac-041847	Gasterosteus aculeatus	63.25	9.00e-61	223.00
IUUC-Gma-044131	Glycine max	58.78	1.00e-38	150.00
IUUC-Ggo-045202	Gorilla gorilla	62.65	2.00e-59	219.00
IUUC-Hsa-046369	Homo sapiens	62.65	2.00e-59	219.00
IUUC-Hvu-047065	Hordeum vulgare	57.05	7.00e-45	172.00
IUUC-Itr-048349	Ictidomys tridecemlineatus	63.86	4.00e-60	221.00
IUUC-Kpa-049317	Komagataella pastoris	63.41	5.00e-61	224.00
IUUC-Lch-049596	Latimeria chalumnae	63.87	1.00e-56	210.00
IUUC-Lpe-051124	Leersia perrieri	57.24	1.00e-43	167.00
IUUC-Loc-052277	Lepisosteus oculatus	60.54	5.00e-47	178.00
IUUC-Lma-053126	Leptosphaeria maculans	81.20	7.00e-62	226.00
IUUC-Laf-054560	Loxodonta africana	61.88	1.00e-56	210.00
IUUC-Mcc-055172	Macaca mulatta	62.65	2.00e-59	219.00
IUUC-Meu-056891	Macropus eugenii	62.03	1.00e-55	206.00
IUUC-Mor-057260	Magnaporthe oryzae	81.10	2.00e-80	289.00
IUUC-Mpo-057468	Magnaporthe poae	81.10	2.00e-79	286.00
IUUC-Mtr-058406	Medicago truncatula	59.46	3.00e-45	172.00
IUUC-Mla-059084	Melampsora laricipopulina	60.69	3.00e-57	212.00
IUUC-Mga-059939	Meleagris gallopavo	61.39	2.00e-55	206.00
IUUC-Mvi-060514	Microbotryum violaceum	62.05	4.00e-57	211.00
IUUC-Mmr-061029	Microcebus murinus	59.17	3.00e-53	198.00
IUUC-Mdo-061820	Monodelphis domestica	63.25	5.00e-60	221.00
IUUC-Mmu-063123	Mus musculus	62.65	2.00e-59	219.00
IUUC-Mac-065294	Musa acuminata	56.67	2.00e-43	166.00
IUUC-Mpu-065866	Mustela putorius furo	59.04	1.00e-55	206.00
IUUC-Mlu-067220	Myotis lucifugus	61.39	1.00e-55	206.00
IUUC-Nfi-068395	Neosartorya fischeri	99.40	6.00e-97	343.00
IUUC-Ncr-068623	Neurospora crassa	79.27	1.00e-76	276.00
IUUC-Nle-070007	Nomascus leucogenys	62.65	2.00e-59	219.00
IUUC-Opr-070958	Ochotona princeps	60.81	1.00e-47	179.00
IUUC-Ont-071736	Oreochromis niloticus	64.46	1.00e-61	226.00
IUUC-Oan-073475	Ornithorhynchus anatinus	58.79	2.00e-55	206.00
IUUC-Ocu-074820	Oryctolagus cuniculus	64.05	9.00e-56	207.00
IUUC-Oba-075915	Oryza barthii	57.93	5.00e-49	184.00
IUUC-Obr-076863	Oryza brachyantha	56.55	2.00e-42	163.00
IUUC-Ogl-076981	Oryza glaberrima	57.93	5.00e-49	184.00
IUUC-Ogu-078183	Oryza glumaepatula	57.93	5.00e-49	184.00
IUUC-Oin-079755	Oryza indica	57.93	5.00e-49	184.00
IUUC-Olo-080576	Oryza longistaminata	57.93	5.00e-49	184.00
IUUC-Ome-081190	Oryza meridionalis	54.90	9.00e-47	177.00
IUUC-Oni-083010	Oryza nivara	57.93	5.00e-49	184.00
IUUC-Opu-083784	Oryza punctata	57.24	2.00e-43	166.00
IUUC-Oru-084817	Oryza rufipogon	57.93	5.00e-49	184.00
IUUC-Osa-085291	Oryza sativa	57.93	5.00e-49	184.00
IUUC-Ola-087571	Oryzias latipes	63.86	4.00e-61	224.00
IUUC-Olu-087887	Ostreococcus lucimarinus	55.21	6.00e-50	187.00
IUUC-Oga-088473	Otolemur garnettii	57.67	5.00e-48	181.00
IUUC-Oar-089706	Ovis aries	62.65	2.00e-59	219.00
IUUC-Ptr-090798	Pan troglodytes	62.65	2.00e-59	219.00
IUUC-Pan-091967	Papio anubis	62.65	2.00e-59	219.00
IUUC-Psi-093524	Pelodiscus sinensis	65.56	5.00e-56	207.00
IUUC-Pma-094602	Petromyzon marinus	67.14	1.00e-52	196.00
IUUC-Pno-094979	Phaeosphaeria nodorum	80.12	5.00e-78	281.00
IUUC-Ppa-095611	Physcomitrella patens	59.12	1.00e-52	196.00
IUUC-Pfo-097330	Poecilia formosa	64.46	3.00e-61	225.00
IUUC-Pab-098225	Pongo abelii	62.05	8.00e-59	217.00
IUUC-Pop-099881	Populus trichocarpa	57.76	4.00e-48	181.00
IUUC-Pca-101040	Procavia capensis	62.34	8.00e-55	203.00
IUUC-Ppe-101778	Prunus persica	59.06	1.00e-45	173.00
IUUC-Pva-103074	Pteropus vampyrus	60.54	1.00e-46	177.00
IUUC-Pgr-103674	Puccinia graminis	58.72	1.00e-54	203.00
IUUC-Ptt-103840	Puccinia triticina	56.98	1.00e-53	200.00
IUUC-Pte-104389	Pyrenophora teres	80.12	5.00e-78	281.00
IUUC-Pyt-104703	Pyrenophora triticirepentis	80.72	4.00e-78	281.00
IUUC-Rno-105228	Rattus norvegicus	62.65	2.00e-59	219.00
IUUC-Sce-106233	Saccharomyces cerevisiae	61.45	2.00e-58	216.00
IUUC-Sha-107274	Sarcophilus harrisii	61.45	9.00e-57	210.00
IUUC-Sja-107937	Schizosaccharomyces japonicus	67.68	2.00e-64	235.00
IUUC-Spo-108269	Schizosaccharomyces pombe	68.29	3.00e-64	235.00
IUUC-Ssl-108636	Sclerotinia sclerotiorum	82.42	3.00e-80	288.00
IUUC-Smo-109401	Selaginella moellendorffii	56.12	1.00e-36	144.00
IUUC-Sit-110784	Setaria italica	58.33	6.00e-44	167.00
IUUC-Sly-111843	Solanum lycopersicum	59.33	2.00e-45	172.00
IUUC-Stu-112865	Solanum tuberosum	57.24	2.00e-45	173.00
IUUC-Sar-112992	Sorex araneus	50.91	1.00e-38	150.00
IUUC-Sbi-113787	Sorghum bicolor	52.44	5.00e-45	171.00
IUUC-Sre-114952	Sporisorium reilianum	62.05	3.00e-57	212.00
IUUC-Ssc-115365	Sus scrofa	62.34	5.00e-55	204.00
IUUC-Tgu-116816	Taeniopygia guttata	63.25	7.00e-60	220.00
IUUC-Tru-118443	Takifugu rubripes	55.48	9.00e-48	180.00
IUUC-Tsy-119168	Tarsius syrichta	60.54	1.00e-46	177.00
IUUC-Tni-120278	Tetraodon nigroviridis	62.87	3.00e-58	215.00
IUUC-Tca-121649	Theobroma cacao	55.41	4.00e-42	161.00
IUUC-Tre-122131	Trichoderma reesei	81.21	2.00e-78	282.00
IUUC-Tvi-122669	Trichoderma virens	81.82	1.00e-79	286.00
IUUC-Tae-123772	Triticum aestivum	56.17	5.00e-47	178.00
IUUC-Tur-126873	Triticum urartu	56.46	2.00e-44	171.00
IUUC-Tme-127052	Tuber melanosporum	68.90	4.00e-65	238.00
IUUC-Tbe-127792	Tupaia belangeri	62.65	2.00e-59	219.00
IUUC-Ttr-128609	Tursiops truncatus	60.54	1.00e-46	177.00
IUUC-Uma-129587	Ustilago maydis	62.05	1.00e-57	213.00
IUUC-Vda-129914	Verticillium dahliae	80.61	2.00e-79	285.00
IUUC-Vpa-130208	Vicugna pacos	60.81	1.00e-47	180.00
IUUC-Vvi-131730	Vitis vinifera	60.00	5.00e-44	168.00
IUUC-Xtr-132450	Xenopus tropicalis	63.86	5.00e-61	224.00
IUUC-Xma-133016	Xiphophorus maculatus	64.46	3.00e-61	225.00
IUUC-Yli-134379	Yarrowia lipolytica	67.07	6.00e-65	237.00
IUUC-Zma-135764	Zea mays	55.33	6.00e-44	167.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence