iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	1.30e-06	28.5	18	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 13   ltlk.vnpsdtVaeLKekiekk.lgippeqqrLiyk..GkiLeddktLadyglkdgstihll 70
            tl+ ++ s+t++ +K++i +k l++ +e+q+L ++  Gk+L dd++L+d+gl   ++++l+
   Q: 18   ITLEgISGSETIKAIKKRIAQKkLKLTEERQALRVEpkGKPLADDQKLSDLGL-SSQKAVLY 78
           56777899***********6666***********9999**************9.55555555 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Catalyzes the last of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme reduces the trans-2,3-enoyl-CoA fatty acid intermediate to an acyl-CoA that can be further elongated by entering a new cycle of elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Protein Sequence
(Fasta)

MSGILEVYDA KRTDNLIITL EGISGSETIK AIKKRIAQKK LKLTEERQAL RVEPKGKPLA 60
DDQKLSDLGL SSQKAVLYVR DLGPQIAWKT VFMAEYAGPL FVYPLFYLRP TFIYGQAAVN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGAGTGGG ATTCTGGAGG TTTATGACGC AAAGCGTACG GACAATCTCA TCATCACCCT 60
CGAGGGAATT TCTGGATCCG AAACGATCAA AGCTATCAAG AAGCGAATTG CCCAGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0275--Fatty acid biosynthesis
KW-0276--Fatty acid metabolism
KW-0444--Lipid biosynthesis
KW-0443--Lipid metabolism
KW-0472--Membrane
KW-0521--NADP
KW-0560--Oxidoreductase
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001104--3-oxo-5_a-steroid_4-DH_C
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50244--S5A_REDUCTASE
PS50053--UBIQUITIN_2

Pfam

PF02544--Steroid_dh
PF00240--ubiquitin

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0016491--F:oxidoreductase activity
GO:0016627--F:oxidoreductase activity, acting on the CH-CH group of donors
GO:0042761--P:very long-chain fatty acid biosynthetic process

KEGG

cel:CELE_C15F1.6

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000125	Aegilops tauschii	37.16	1.00e-50	191.00
IUUC-Aml-001579	Ailuropoda melanoleuca	57.79	8.00e-89	319.00
IUUC-Atr-002693	Amborella trichopoda	38.79	4.00e-42	163.00
IUUC-Apl-004113	Anas platyrhynchos	47.87	2.00e-85	307.00
IUUC-Aca-004681	Anolis carolinensis	51.15	1.00e-90	325.00
IUUC-Aly-005795	Arabidopsis lyrata	37.67	3.00e-45	174.00
IUUC-Ath-007255	Arabidopsis thaliana	37.24	1.00e-45	175.00
IUUC-Ago-007822	Ashbya gossypii	32.99	3.00e-30	124.00
IUUC-Acl-008131	Aspergillus clavatus	41.25	8.00e-40	155.00
IUUC-Afl-008670	Aspergillus flavus	34.32	4.00e-33	134.00
IUUC-Afu-009058	Aspergillus fumigatus	39.38	7.00e-37	146.00
IUUC-Ani-009299	Aspergillus nidulans	41.38	2.00e-38	151.00
IUUC-Ang-009520	Aspergillus niger	38.67	2.00e-40	158.00
IUUC-Aor-010023	Aspergillus oryzae	41.02	1.00e-42	165.00
IUUC-Ate-010593	Aspergillus terreus	39.85	6.00e-40	156.00
IUUC-Ame-011087	Astyanax mexicanus	49.84	2.00e-88	317.00
IUUC-Bgr-012251	Blumeria graminis	31.15	1.00e-36	145.00
IUUC-Bta-013170	Bos taurus	53.11	6.00e-93	332.00
IUUC-Bci-013894	Botrytis cinerea	33.66	2.00e-41	161.00
IUUC-Bdi-015014	Brachypodium distachyon	38.52	6.00e-51	192.00
IUUC-Bol-015761	Brassica oleracea	38.01	5.00e-46	176.00
IUUC-Bra-016894	Brassica rapa	37.67	2.00e-45	174.00
IUUC-Cja-019333	Callithrix jacchus	51.80	9.00e-90	322.00
IUUC-Cfa-020709	Canis familiaris	53.11	5.00e-93	333.00
IUUC-Cpo-022353	Cavia porcellus	53.11	4.00e-93	333.00
IUUC-Cre-023020	Chlamydomonas reinhardtii	43.49	1.00e-58	218.00
IUUC-Csa-023716	Chlorocebus sabaeus	53.11	3.00e-93	333.00
IUUC-Csv-025915	Ciona savignyi	53.44	8.00e-91	325.00
IUUC-Cgl-026580	Colletotrichum gloeosporioides	34.72	3.00e-41	160.00
IUUC-Cne-027086	Cryptococcus neoformans	28.33	4.00e-23	100.00
IUUC-Cme-027185	Cyanidioschyzon merolae	43.58	1.00e-65	241.00
IUUC-Dre-028710	Danio rerio	49.51	8.00e-89	318.00
IUUC-Dno-029631	Dasypus novemcinctus	39.55	7.00e-55	206.00
IUUC-Dor-030220	Dipodomys ordii	52.79	7.00e-93	332.00
IUUC-Dse-031218	Dothistroma septosporum	38.30	2.00e-49	187.00
IUUC-Dme-031792	Drosophila melanogaster	53.79	4.00e-83	299.00
IUUC-Ete-032441	Echinops telfairi	55.63	3.00e-43	167.00
IUUC-Eca-033372	Equus caballus	53.11	3.00e-93	333.00
IUUC-Eeu-035351	Erinaceus europaeus	37.38	3.00e-42	163.00
IUUC-Fca-035630	Felis catus	53.11	4.00e-93	333.00
IUUC-Fal-037646	Ficedula albicollis	46.37	2.00e-64	237.00
IUUC-Fox-037721	Fusarium oxysporum	34.62	4.00e-36	143.00
IUUC-Fso-038379	Fusarium solani	32.40	3.00e-38	150.00
IUUC-Gmo-039616	Gadus morhua	45.30	6.00e-77	279.00
IUUC-Ggr-039727	Gaeumannomyces graminis	30.46	1.00e-31	128.00
IUUC-Gga-040786	Gallus gallus	49.81	4.00e-75	273.00
IUUC-Gac-041971	Gasterosteus aculeatus	46.89	4.00e-81	293.00
IUUC-Gma-043815	Glycine max	36.58	2.00e-43	167.00
IUUC-Ggo-045138	Gorilla gorilla	43.93	1.00e-67	248.00
IUUC-Hsa-045822	Homo sapiens	53.11	5.00e-93	332.00
IUUC-Hvu-047496	Hordeum vulgare	37.21	9.00e-52	195.00
IUUC-Itr-048022	Ictidomys tridecemlineatus	57.41	1.00e-88	318.00
IUUC-Kpa-049334	Komagataella pastoris	33.45	2.00e-39	154.00
IUUC-Lch-050175	Latimeria chalumnae	50.49	7.00e-88	315.00
IUUC-Lpe-051290	Leersia perrieri	39.61	4.00e-51	193.00
IUUC-Loc-052055	Lepisosteus oculatus	49.84	1.00e-87	315.00
IUUC-Lma-053284	Leptosphaeria maculans	37.35	6.00e-45	172.00
IUUC-Laf-053677	Loxodonta africana	53.11	6.00e-93	332.00
IUUC-Mcc-055371	Macaca mulatta	51.48	4.00e-87	313.00
IUUC-Meu-056786	Macropus eugenii	50.52	6.00e-82	295.00
IUUC-Mor-057062	Magnaporthe oryzae	33.66	1.00e-38	152.00
IUUC-Mpo-057319	Magnaporthe poae	31.49	3.00e-33	134.00
IUUC-Mtr-058159	Medicago truncatula	37.46	5.00e-43	166.00
IUUC-Mla-058998	Melampsora laricipopulina	34.62	1.00e-39	155.00
IUUC-Mga-059715	Meleagris gallopavo	47.87	2.00e-85	307.00
IUUC-Mvi-060498	Microbotryum violaceum	37.65	3.00e-47	181.00
IUUC-Mmr-061604	Microcebus murinus	52.79	7.00e-93	332.00
IUUC-Mdo-062723	Monodelphis domestica	53.11	1.00e-93	334.00
IUUC-Mmu-064423	Mus musculus	50.82	1.00e-86	311.00
IUUC-Mac-064557	Musa acuminata	35.33	8.00e-45	172.00
IUUC-Mpu-065790	Mustela putorius furo	53.11	3.00e-93	333.00
IUUC-Mlu-067323	Myotis lucifugus	53.11	5.00e-93	332.00
IUUC-Nfi-068303	Neosartorya fischeri	40.15	2.00e-37	148.00
IUUC-Ncr-068930	Neurospora crassa	34.46	4.00e-35	140.00
IUUC-Nle-069641	Nomascus leucogenys	53.11	3.00e-93	333.00
IUUC-Opr-070264	Ochotona princeps	39.13	3.00e-39	154.00
IUUC-Ont-072619	Oreochromis niloticus	49.51	9.00e-88	315.00
IUUC-Oan-072871	Ornithorhynchus anatinus	52.46	3.00e-92	330.00
IUUC-Ocu-074116	Oryctolagus cuniculus	40.00	2.00e-62	231.00
IUUC-Oba-075519	Oryza barthii	38.11	3.00e-51	193.00
IUUC-Obr-076026	Oryza brachyantha	36.19	2.00e-51	194.00
IUUC-Ogl-077299	Oryza glaberrima	38.87	3.00e-52	197.00
IUUC-Ogu-078328	Oryza glumaepatula	40.08	4.00e-51	193.00
IUUC-Oin-079058	Oryza indica	38.87	3.00e-52	197.00
IUUC-Olo-080760	Oryza longistaminata	39.41	4.00e-46	177.00
IUUC-Ome-081290	Oryza meridionalis	38.11	3.00e-51	193.00
IUUC-Oni-082116	Oryza nivara	37.98	2.00e-51	194.00
IUUC-Opu-083484	Oryza punctata	37.76	3.00e-50	190.00
IUUC-Oru-085234	Oryza rufipogon	37.98	2.00e-51	194.00
IUUC-Osa-085723	Oryza sativa	38.87	3.00e-52	197.00
IUUC-Ola-087142	Oryzias latipes	48.85	1.00e-86	311.00
IUUC-Olu-087663	Ostreococcus lucimarinus	37.96	9.00e-51	192.00
IUUC-Oga-088511	Otolemur garnettii	53.11	4.00e-93	332.00
IUUC-Oar-090337	Ovis aries	62.07	7.00e-66	242.00
IUUC-Ptr-090829	Pan troglodytes	52.79	2.00e-92	330.00
IUUC-Pan-091853	Papio anubis	51.91	5.00e-75	273.00
IUUC-Psi-093244	Pelodiscus sinensis	57.42	2.00e-85	307.00
IUUC-Pno-094768	Phaeosphaeria nodorum	37.33	2.00e-47	181.00
IUUC-Ppa-095402	Physcomitrella patens	35.84	9.00e-52	195.00
IUUC-Pfo-096308	Poecilia formosa	49.84	3.00e-88	316.00
IUUC-Pab-098622	Pongo abelii	51.39	9.00e-72	261.00
IUUC-Pop-099770	Populus trichocarpa	37.58	5.00e-44	170.00
IUUC-Pca-100732	Procavia capensis	51.80	1.00e-88	318.00
IUUC-Ppe-102094	Prunus persica	37.29	3.00e-53	200.00
IUUC-Pva-103208	Pteropus vampyrus	53.11	5.00e-93	332.00
IUUC-Pgr-103639	Puccinia graminis	30.97	2.00e-26	111.00
IUUC-Ptt-103851	Puccinia triticina	32.89	4.00e-34	137.00
IUUC-Pte-104134	Pyrenophora teres	39.36	1.00e-49	188.00
IUUC-Pyt-104660	Pyrenophora triticirepentis	42.23	7.00e-50	189.00
IUUC-Rno-104826	Rattus norvegicus	52.79	9.00e-93	332.00
IUUC-Sce-106237	Saccharomyces cerevisiae	33.33	6.00e-38	149.00
IUUC-Sha-107453	Sarcophilus harrisii	52.79	7.00e-93	332.00
IUUC-Sja-107686	Schizosaccharomyces japonicus	39.01	3.00e-49	187.00
IUUC-Spo-108110	Schizosaccharomyces pombe	40.16	5.00e-49	186.00
IUUC-Smo-108765	Selaginella moellendorffii	35.71	1.00e-48	185.00
IUUC-Sit-110416	Setaria italica	38.01	5.00e-51	193.00
IUUC-Sly-111184	Solanum lycopersicum	38.00	1.00e-53	201.00
IUUC-Stu-112187	Solanum tuberosum	38.13	3.00e-54	203.00
IUUC-Sar-113576	Sorex araneus	40.00	2.00e-23	101.00
IUUC-Sbi-114251	Sorghum bicolor	38.36	3.00e-51	193.00
IUUC-Sre-114975	Sporisorium reilianum	42.95	8.00e-61	225.00
IUUC-Ssc-115522	Sus scrofa	57.79	2.00e-89	320.00
IUUC-Tgu-116610	Taeniopygia guttata	46.60	7.00e-84	302.00
IUUC-Tru-118204	Takifugu rubripes	49.18	4.00e-87	313.00
IUUC-Tsy-119153	Tarsius syrichta	35.41	2.00e-52	197.00
IUUC-Tni-119738	Tetraodon nigroviridis	49.02	6.00e-87	312.00
IUUC-Tca-120950	Theobroma cacao	37.74	3.00e-52	197.00
IUUC-Tre-122109	Trichoderma reesei	34.44	3.00e-37	147.00
IUUC-Tvi-122473	Trichoderma virens	33.67	4.00e-37	147.00
IUUC-Tae-123617	Triticum aestivum	37.21	8.00e-52	196.00
IUUC-Tur-126035	Triticum urartu	40.00	4.00e-46	176.00
IUUC-Tme-127040	Tuber melanosporum	33.11	1.00e-36	145.00
IUUC-Tbe-127888	Tupaia belangeri	41.38	2.00e-32	131.00
IUUC-Ttr-128486	Tursiops truncatus	53.11	3.00e-93	333.00
IUUC-Uma-129516	Ustilago maydis	42.81	2.00e-59	221.00
IUUC-Vda-129861	Verticillium dahliae	34.26	1.00e-34	138.00
IUUC-Vpa-130704	Vicugna pacos	35.62	6.00e-53	199.00
IUUC-Vvi-131375	Vitis vinifera	38.98	6.00e-53	199.00
IUUC-Xtr-132795	Xenopus tropicalis	52.46	1.00e-90	324.00
IUUC-Xma-133866	Xiphophorus maculatus	49.84	3.00e-88	317.00
IUUC-Yli-134568	Yarrowia lipolytica	36.59	4.00e-46	176.00
IUUC-Zma-134891	Zea mays	37.04	5.00e-51	193.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence