iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010977

Ensembl Protein ID

ENSAMXP00000006498.1

UniProt Accession

W5KFY7; W5KFY7_ASTMX

Genbank Protein ID

ENSAMXP00000006498

Protein Name

Protein kinase C

Genbank Nucleotide ID

APWO01024063

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000006328.1	ENSAMXT00000006498.1	ENSAMXP00000006498.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	1.70e-21	76.5	18	99

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
           +vrvk++y+g+i  + +++e+++++e L+++vr++++l+n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l ++++
   Q: 18   QVRVKAYYRGDI--MITHFEPSISYEGLYSEVRDMCSLDNdQLFTMKWIDEEGDPCTVSSQLELEEALRLYElNKDSELIIHVF 99
           69**********..88******************************************************************98 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MPTVRDSTAT HPGENQHQVR VKAYYRGDIM ITHFEPSISY EGLYSEVRDM CSLDNDQLFT 60
MKWIDEEGDP CTVSSQLELE EALRLYELNK DSELIIHVFP CIPEKPGMPC PGEDKSIYRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGACGG TGCGGGACAG CACTGCGACC CACCCGGGGG AGAACCAGCA CCAGGTCCGG 60
GTGAAGGCCT ACTACCGCGG GTGAGTTCGC GTTAGTTTAC TATTTTAAGT CTATATATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005622--C:intracellular
GO:0031226--C:intrinsic component of plasma membrane
GO:0005915--C:zonula adherens
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004697--F:protein kinase C activity
GO:0034334--P:adherens junction maintenance
GO:0045217--P:cell-cell junction maintenance
GO:0007502--P:digestive tract mesoderm development
GO:0048546--P:digestive tract morphogenesis
GO:0021744--P:dorsal motor nucleus of vagus nerve development
GO:0035050--P:embryonic heart tube development
GO:0000132--P:establishment of mitotic spindle orientation
GO:0016332--P:establishment or maintenance of polarity of embryonic epithelium
GO:0035556--P:intracellular signal transduction
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0008078--P:mesodermal cell migration
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0001841--P:neural tube formation
GO:0007405--P:neuroblast proliferation
GO:0007097--P:nuclear migration
GO:0042476--P:odontogenesis
GO:0035845--P:photoreceptor cell outer segment organization
GO:0035778--P:pronephric nephron tubule epithelial cell differentiation
GO:0060042--P:retina morphogenesis in camera-type eye
GO:0021591--P:ventricular system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	89.12	0.00e+00	909.00
IUUC-Apl-003711	Anas platyrhynchos	89.18	0.00e+00	983.00
IUUC-Aca-005142	Anolis carolinensis	88.66	0.00e+00	999.00
IUUC-Bta-013414	Bos taurus	87.75	0.00e+00	1026.00
IUUC-Cel-018340	Caenorhabditis elegans	58.21	0.00e+00	691.00
IUUC-Cja-019802	Callithrix jacchus	89.17	0.00e+00	987.00
IUUC-Cfa-021236	Canis familiaris	87.08	0.00e+00	1010.00
IUUC-Cpo-022127	Cavia porcellus	87.48	0.00e+00	959.00
IUUC-Csa-023332	Chlorocebus sabaeus	89.42	0.00e+00	841.00
IUUC-Cho-025054	Choloepus hoffmanni	91.87	3.00e-60	226.00
IUUC-Cin-025740	Ciona intestinalis	59.86	0.00e+00	691.00
IUUC-Csv-026145	Ciona savignyi	77.36	8.00e-172	596.00
IUUC-Dre-028444	Danio rerio	92.36	0.00e+00	1043.00
IUUC-Dno-029228	Dasypus novemcinctus	96.77	3.00e-177	613.00
IUUC-Dme-031630	Drosophila melanogaster	79.83	2.00e-168	585.00
IUUC-Ete-032633	Echinops telfairi	67.21	1.00e-168	585.00
IUUC-Eca-033572	Equus caballus	89.50	0.00e+00	992.00
IUUC-Eeu-035110	Erinaceus europaeus	88.91	0.00e+00	1016.00
IUUC-Fca-035559	Felis catus	87.92	0.00e+00	1028.00
IUUC-Fal-036953	Ficedula albicollis	89.68	0.00e+00	988.00
IUUC-Gmo-039334	Gadus morhua	90.51	0.00e+00	1045.00
IUUC-Gga-040223	Gallus gallus	86.81	0.00e+00	1016.00
IUUC-Gac-042113	Gasterosteus aculeatus	91.51	0.00e+00	1056.00
IUUC-Ggo-044520	Gorilla gorilla	83.74	0.00e+00	936.00
IUUC-Hsa-046991	Homo sapiens	87.42	0.00e+00	1022.00
IUUC-Lch-050263	Latimeria chalumnae	85.91	0.00e+00	991.00
IUUC-Loc-052221	Lepisosteus oculatus	90.32	0.00e+00	1008.00
IUUC-Laf-053591	Loxodonta africana	87.92	0.00e+00	1027.00
IUUC-Mcc-055118	Macaca mulatta	87.10	0.00e+00	1015.00
IUUC-Mga-059886	Meleagris gallopavo	89.18	0.00e+00	983.00
IUUC-Mmr-060926	Microcebus murinus	87.75	0.00e+00	1025.00
IUUC-Mdo-062698	Monodelphis domestica	84.60	0.00e+00	986.00
IUUC-Mmu-063689	Mus musculus	87.42	0.00e+00	1017.00
IUUC-Mpu-066630	Mustela putorius furo	88.66	0.00e+00	1018.00
IUUC-Mlu-067416	Myotis lucifugus	85.09	0.00e+00	971.00
IUUC-Nle-069811	Nomascus leucogenys	87.42	0.00e+00	1021.00
IUUC-Opr-070466	Ochotona princeps	79.82	0.00e+00	666.00
IUUC-Ont-072278	Oreochromis niloticus	88.41	0.00e+00	972.00
IUUC-Oan-073651	Ornithorhynchus anatinus	95.30	0.00e+00	701.00
IUUC-Ocu-074383	Oryctolagus cuniculus	87.75	0.00e+00	1025.00
IUUC-Ola-087283	Oryzias latipes	97.42	6.00e-159	553.00
IUUC-Oga-088337	Otolemur garnettii	80.70	0.00e+00	915.00
IUUC-Oar-089954	Ovis aries	89.34	0.00e+00	997.00
IUUC-Ptr-091673	Pan troglodytes	87.42	0.00e+00	1022.00
IUUC-Pan-092494	Papio anubis	87.58	0.00e+00	1025.00
IUUC-Psi-094044	Pelodiscus sinensis	87.41	0.00e+00	1004.00
IUUC-Pfo-096661	Poecilia formosa	87.73	0.00e+00	1001.00
IUUC-Pab-097659	Pongo abelii	87.25	0.00e+00	1018.00
IUUC-Pca-101107	Procavia capensis	90.77	0.00e+00	699.00
IUUC-Rno-105790	Rattus norvegicus	87.58	0.00e+00	1021.00
IUUC-Sha-106895	Sarcophilus harrisii	89.05	0.00e+00	969.00
IUUC-Sar-113513	Sorex araneus	84.11	2.00e-149	522.00
IUUC-Ssc-115835	Sus scrofa	88.89	0.00e+00	910.00
IUUC-Tgu-116874	Taeniopygia guttata	87.02	0.00e+00	1012.00
IUUC-Tru-117823	Takifugu rubripes	89.12	0.00e+00	1000.00
IUUC-Tsy-119154	Tarsius syrichta	89.50	0.00e+00	992.00
IUUC-Tni-119968	Tetraodon nigroviridis	87.83	0.00e+00	996.00
IUUC-Tbe-127238	Tupaia belangeri	70.85	0.00e+00	664.00
IUUC-Ttr-129208	Tursiops truncatus	87.44	0.00e+00	1024.00
IUUC-Vpa-130363	Vicugna pacos	79.03	0.00e+00	894.00
IUUC-Xtr-132652	Xenopus tropicalis	82.54	0.00e+00	954.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence