iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117823

Ensembl Protein ID

ENSTRUP00000013497.1

UniProt Accession

H2SM61; H2SM61_TAKRU

Protein Name

Protein kinase C

Gene Name

prkci

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000005596.1	ENSTRUT00000013559.1	ENSTRUP00000013497.1
ENSTRUG00000005596.1	ENSTRUT00000013560.1	ENSTRUP00000013498.1
ENSTRUG00000005596.1	ENSTRUT00000013561.1	ENSTRUP00000013499.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	2.50e-20	73.7	10	91

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirsfaldlekpgkfedLlkavrtltelkn.sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
           +vrvk++ykg+i  + +++e+++++e L+ +vr++++++n + +++k+ De+GD +t++s+ +l++a++l++ +k+s l ++++
   Q: 10   QVRVKAYYKGDI--MITHFEPSISYEGLYGEVRDMCSMDNdQVFTMKWIDEEGDPCTVSSQLELEEALRLYElNKDSELIIHVF 91
           69**********..88************************999***************************************98 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MSHPGENSHQ VRVKAYYKGD IMITHFEPSI SYEGLYGEVR DMCSMDNDQV FTMKWIDEEG 60
DPCTVSSQLE LEEALRLYEL NKDSELIIHV FPCVPEKPGM PCPGEDKSIY RRGARRWRKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCACC CCGGCGAGAA TTCCCACCAA GTCCGGGTTA AAGCTTATTA TAAAGGGTAA 60
GGAACCATCC TATGAATTAA TATGTTAAGA ACATCACTAC CATTTAAACT AGTAGCAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000961--AGC-kinase_C
IPR020454--DAG/PE-bd
IPR011009--Kinase-like_dom
IPR000270--PB1_dom
IPR002219--PE/DAG-bd
IPR012233--PKC
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS51285--AGC_KINASE_CTER
PS51745--PB1
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF00564--PB1
PF00069--Pkinase
PF00433--Pkinase_C

PRINTS

PR00008--DAGPEDOMAIN

SMART

SM00109--C1
SM00666--PB1
SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005622--C:intracellular
GO:0031226--C:intrinsic component of plasma membrane
GO:0005915--C:zonula adherens
GO:0005524--F:ATP binding
GO:0046872--F:metal ion binding
GO:0004697--F:protein kinase C activity
GO:0004674--F:protein serine/threonine kinase activity
GO:0034334--P:adherens junction maintenance
GO:0045217--P:cell-cell junction maintenance
GO:0007502--P:digestive tract mesoderm development
GO:0048546--P:digestive tract morphogenesis
GO:0021744--P:dorsal motor nucleus of vagus nerve development
GO:0035050--P:embryonic heart tube development
GO:0000132--P:establishment of mitotic spindle orientation
GO:0016332--P:establishment or maintenance of polarity of embryonic epithelium
GO:0035556--P:intracellular signal transduction
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0008078--P:mesodermal cell migration
GO:0001738--P:morphogenesis of a polarized epithelium
GO:0001841--P:neural tube formation
GO:0007405--P:neuroblast proliferation
GO:0007097--P:nuclear migration
GO:0042476--P:odontogenesis
GO:0018105--P:peptidyl-serine phosphorylation
GO:0035845--P:photoreceptor cell outer segment organization
GO:0035778--P:pronephric nephron tubule epithelial cell differentiation
GO:0060042--P:retina morphogenesis in camera-type eye
GO:0021591--P:ventricular system development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001764	Ailuropoda melanoleuca	88.16	0.00e+00	916.00
IUUC-Apl-003711	Anas platyrhynchos	88.27	0.00e+00	980.00
IUUC-Aca-005142	Anolis carolinensis	87.63	0.00e+00	998.00
IUUC-Ame-010977	Astyanax mexicanus	88.44	0.00e+00	995.00
IUUC-Bta-013414	Bos taurus	87.23	0.00e+00	1027.00
IUUC-Cel-018340	Caenorhabditis elegans	57.40	0.00e+00	691.00
IUUC-Cja-019802	Callithrix jacchus	88.09	0.00e+00	993.00
IUUC-Cfa-021236	Canis familiaris	88.21	0.00e+00	1006.00
IUUC-Cpo-022127	Cavia porcellus	86.26	0.00e+00	962.00
IUUC-Csa-023332	Chlorocebus sabaeus	88.37	0.00e+00	850.00
IUUC-Cho-025054	Choloepus hoffmanni	91.87	3.00e-60	226.00
IUUC-Cin-025740	Ciona intestinalis	60.68	0.00e+00	697.00
IUUC-Csv-026145	Ciona savignyi	77.42	1.00e-171	596.00
IUUC-Dre-028444	Danio rerio	91.00	0.00e+00	1026.00
IUUC-Dno-029228	Dasypus novemcinctus	97.10	1.00e-177	615.00
IUUC-Dme-031630	Drosophila melanogaster	64.84	0.00e+00	763.00
IUUC-Ete-032633	Echinops telfairi	65.93	9.00e-167	579.00
IUUC-Eca-033572	Equus caballus	88.25	0.00e+00	998.00
IUUC-Eeu-035110	Erinaceus europaeus	86.87	0.00e+00	1020.00
IUUC-Fca-035559	Felis catus	87.06	0.00e+00	1028.00
IUUC-Fal-036953	Ficedula albicollis	88.27	0.00e+00	984.00
IUUC-Gmo-039334	Gadus morhua	92.53	0.00e+00	1074.00
IUUC-Gga-040223	Gallus gallus	87.86	0.00e+00	1006.00
IUUC-Gac-042113	Gasterosteus aculeatus	93.72	0.00e+00	1092.00
IUUC-Ggo-044520	Gorilla gorilla	83.30	0.00e+00	942.00
IUUC-Hsa-046991	Homo sapiens	88.21	0.00e+00	1028.00
IUUC-Lch-050263	Latimeria chalumnae	86.08	0.00e+00	1000.00
IUUC-Loc-052221	Lepisosteus oculatus	89.64	0.00e+00	1005.00
IUUC-Laf-053591	Loxodonta africana	88.38	0.00e+00	1027.00
IUUC-Mcc-055118	Macaca mulatta	87.35	0.00e+00	1007.00
IUUC-Mga-059886	Meleagris gallopavo	88.44	0.00e+00	980.00
IUUC-Mmr-060926	Microcebus murinus	88.03	0.00e+00	1026.00
IUUC-Mdo-062698	Monodelphis domestica	86.30	0.00e+00	988.00
IUUC-Mmu-063689	Mus musculus	88.03	0.00e+00	1016.00
IUUC-Mpu-066630	Mustela putorius furo	88.03	0.00e+00	1023.00
IUUC-Mlu-067416	Myotis lucifugus	84.23	0.00e+00	964.00
IUUC-Nle-069811	Nomascus leucogenys	88.03	0.00e+00	1026.00
IUUC-Opr-070466	Ochotona princeps	78.85	0.00e+00	672.00
IUUC-Ont-072278	Oreochromis niloticus	91.70	0.00e+00	1020.00
IUUC-Oan-073651	Ornithorhynchus anatinus	95.30	0.00e+00	702.00
IUUC-Ocu-074383	Oryctolagus cuniculus	88.03	0.00e+00	1024.00
IUUC-Ola-087283	Oryzias latipes	86.64	0.00e+00	845.00
IUUC-Oga-088337	Otolemur garnettii	80.95	0.00e+00	917.00
IUUC-Oar-089954	Ovis aries	88.27	0.00e+00	1002.00
IUUC-Ptr-091673	Pan troglodytes	88.21	0.00e+00	1028.00
IUUC-Pan-092494	Papio anubis	88.21	0.00e+00	1025.00
IUUC-Psi-094044	Pelodiscus sinensis	86.64	0.00e+00	1011.00
IUUC-Pfo-096661	Poecilia formosa	91.05	0.00e+00	1035.00
IUUC-Pab-097659	Pongo abelii	87.69	0.00e+00	1019.00
IUUC-Pca-101107	Procavia capensis	89.45	0.00e+00	710.00
IUUC-Rno-105790	Rattus norvegicus	88.03	0.00e+00	1021.00
IUUC-Sha-106895	Sarcophilus harrisii	87.80	0.00e+00	976.00
IUUC-Sar-113513	Sorex araneus	82.07	9.00e-151	526.00
IUUC-Ssc-115835	Sus scrofa	87.92	0.00e+00	917.00
IUUC-Tgu-116874	Taeniopygia guttata	88.34	0.00e+00	1008.00
IUUC-Tsy-119154	Tarsius syrichta	88.07	0.00e+00	997.00
IUUC-Tni-119968	Tetraodon nigroviridis	96.13	0.00e+00	1095.00
IUUC-Tbe-127238	Tupaia belangeri	69.98	0.00e+00	664.00
IUUC-Ttr-129208	Tursiops truncatus	86.91	0.00e+00	1025.00
IUUC-Vpa-130363	Vicugna pacos	78.82	0.00e+00	892.00
IUUC-Xtr-132652	Xenopus tropicalis	83.56	0.00e+00	971.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence