iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053765

Ensembl Protein ID

ENSLAFP00000026199.1

UniProt Accession

G3UEE1; G3UEE1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

IFT80

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000017096.4	ENSLAFT00000017097.4	ENSLAFP00000014335.4
ENSLAFG00000017096.4	ENSLAFT00000034559.1	ENSLAFP00000026199.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.00e-13	48.6	13	42

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd.tllvsGsdDgtikvWDl 30
           H++ v+c+ +++   l s+sdD++i  W+l
   Q: 13   HQELVSCVGWTTaEELYSCSDDHQIVKWNL 42
           999*******76799*********876776 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LWCVLCLLNM VTHQELVSCV GWTTAEELYS CSDDHQIVKW NLLTSETSQI VKLPEDIYPI 60
DLHWFPKSLG IKKQTQAESF VLTSSDGKFH LISKLGRVEK SVEAHCGAVL AGRWNYEGTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGCTGA AGATATCTCT TTTAAAAGAA CCAAAACATA TCCTTTTAAT ACTTACTATA 60
GTATTGTTAA AAATTTCCTT TTATTTGGTA TTCTAGTTGG GGAATGCATT ATTATGATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	95.00	0.00e+00	866.00
IUUC-Apl-003721	Anas platyrhynchos	85.52	0.00e+00	1360.00
IUUC-Aca-004488	Anolis carolinensis	84.81	0.00e+00	1364.00
IUUC-Ame-011402	Astyanax mexicanus	80.04	0.00e+00	797.00
IUUC-Bta-013037	Bos taurus	86.42	0.00e+00	1333.00
IUUC-Cel-018360	Caenorhabditis elegans	40.88	0.00e+00	652.00
IUUC-Cja-019076	Callithrix jacchus	93.32	0.00e+00	1212.00
IUUC-Cfa-020999	Canis familiaris	96.11	0.00e+00	1506.00
IUUC-Cpo-021333	Cavia porcellus	85.25	0.00e+00	1288.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	46.49	0.00e+00	672.00
IUUC-Csa-023699	Chlorocebus sabaeus	94.79	0.00e+00	1505.00
IUUC-Cho-024904	Choloepus hoffmanni	85.34	0.00e+00	798.00
IUUC-Cin-025399	Ciona intestinalis	57.60	0.00e+00	951.00
IUUC-Csv-026186	Ciona savignyi	56.00	0.00e+00	919.00
IUUC-Dre-028276	Danio rerio	73.72	0.00e+00	1246.00
IUUC-Dno-029824	Dasypus novemcinctus	95.95	0.00e+00	1534.00
IUUC-Dor-031141	Dipodomys ordii	90.31	0.00e+00	1408.00
IUUC-Dme-031620	Drosophila melanogaster	34.95	2.00e-141	496.00
IUUC-Eca-033339	Equus caballus	93.67	0.00e+00	1467.00
IUUC-Eeu-034909	Erinaceus europaeus	94.39	0.00e+00	1013.00
IUUC-Fca-035780	Felis catus	96.08	0.00e+00	1489.00
IUUC-Fal-037447	Ficedula albicollis	78.32	0.00e+00	1242.00
IUUC-Gmo-038657	Gadus morhua	60.75	0.00e+00	827.00
IUUC-Gga-040689	Gallus gallus	85.29	0.00e+00	1357.00
IUUC-Gac-041586	Gasterosteus aculeatus	71.70	0.00e+00	1014.00
IUUC-Hsa-047005	Homo sapiens	94.18	0.00e+00	1503.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	96.27	0.00e+00	1111.00
IUUC-Lch-050459	Latimeria chalumnae	80.42	0.00e+00	1328.00
IUUC-Loc-052774	Lepisosteus oculatus	78.18	0.00e+00	1061.00
IUUC-Mcc-055052	Macaca mulatta	94.79	0.00e+00	1505.00
IUUC-Meu-056368	Macropus eugenii	80.87	0.00e+00	1253.00
IUUC-Mga-059488	Meleagris gallopavo	86.12	0.00e+00	1364.00
IUUC-Mmr-061527	Microcebus murinus	94.99	0.00e+00	1501.00
IUUC-Mdo-062850	Monodelphis domestica	93.81	0.00e+00	1217.00
IUUC-Mmu-063117	Mus musculus	94.39	0.00e+00	1476.00
IUUC-Mpu-066550	Mustela putorius furo	95.38	0.00e+00	1381.00
IUUC-Mlu-067772	Myotis lucifugus	91.75	0.00e+00	1386.00
IUUC-Nle-069215	Nomascus leucogenys	93.27	0.00e+00	1488.00
IUUC-Opr-070725	Ochotona princeps	73.46	0.00e+00	1116.00
IUUC-Ont-072147	Oreochromis niloticus	73.05	0.00e+00	1245.00
IUUC-Oan-073176	Ornithorhynchus anatinus	84.55	2.00e-61	227.00
IUUC-Ocu-073896	Oryctolagus cuniculus	94.12	0.00e+00	1222.00
IUUC-Ola-086767	Oryzias latipes	66.51	0.00e+00	969.00
IUUC-Oga-088113	Otolemur garnettii	95.48	0.00e+00	1544.00
IUUC-Oar-089683	Ovis aries	91.81	0.00e+00	1439.00
IUUC-Ptr-091563	Pan troglodytes	94.86	0.00e+00	1503.00
IUUC-Pan-092042	Papio anubis	94.79	0.00e+00	1504.00
IUUC-Psi-093306	Pelodiscus sinensis	86.29	0.00e+00	1422.00
IUUC-Ppa-095694	Physcomitrella patens	44.99	0.00e+00	718.00
IUUC-Pfo-096800	Poecilia formosa	72.12	0.00e+00	1217.00
IUUC-Pab-098356	Pongo abelii	94.05	0.00e+00	1499.00
IUUC-Pva-102246	Pteropus vampyrus	90.73	0.00e+00	1407.00
IUUC-Rno-105195	Rattus norvegicus	93.27	0.00e+00	1486.00
IUUC-Sha-107056	Sarcophilus harrisii	93.59	0.00e+00	1472.00
IUUC-Smo-109240	Selaginella moellendorffii	43.16	7.00e-174	603.00
IUUC-Sar-113301	Sorex araneus	86.73	3.00e-150	525.00
IUUC-Ssc-116040	Sus scrofa	94.94	1.00e-144	504.00
IUUC-Tgu-117127	Taeniopygia guttata	81.04	0.00e+00	1291.00
IUUC-Tru-118663	Takifugu rubripes	69.99	0.00e+00	1187.00
IUUC-Tsy-119207	Tarsius syrichta	82.69	0.00e+00	1285.00
IUUC-Tni-120705	Tetraodon nigroviridis	69.21	0.00e+00	1176.00
IUUC-Tbe-127434	Tupaia belangeri	90.85	0.00e+00	942.00
IUUC-Ttr-128937	Tursiops truncatus	95.48	0.00e+00	1508.00
IUUC-Vpa-130518	Vicugna pacos	89.92	0.00e+00	1385.00
IUUC-Xtr-131879	Xenopus tropicalis	77.17	0.00e+00	1261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence