iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048921

Ensembl Protein ID

ENSSTOP00000000244.2

UniProt Accession

I3LWA3; I3LWA3_ICTTR

Genbank Protein ID

ENSSTOP00000000244

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01036817

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000000273.2	ENSSTOT00000000274.2	ENSSTOP00000000244.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-18	67.2	212	279
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	8.10e-07	28.4	311	337

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 212  CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 279
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 311  PSNCLGIRAFADAQGCIELMKVAHSYT 337
           89***********************95 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSGSGRKDFD VKHILRLRWK LFSHPSPSPG SPAGGGCLQQ DSSGSFEHWG PSQSRLLKSQ 60
ERGSVSTFWK KPSSSSSSSS SPSSSSSSFN PLNGTLLPVA TRLQQGAPGQ GTQQPARTLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCATAAACC ATGTCAGGCT CCGGGAGAAA AGACTTCGAT GTGAAGCACA TCCTGCGACT 60
CCGCTGGAAA CTCTTCAGCC ATCCTTCGCC GTCCCCAGGC AGCCCGGCGG GGGGCGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000220	Aegilops tauschii	31.84	2.00e-36	147.00
IUUC-Aml-001478	Ailuropoda melanoleuca	96.80	0.00e+00	1355.00
IUUC-Apl-003408	Anas platyrhynchos	96.06	0.00e+00	1113.00
IUUC-Aca-004384	Anolis carolinensis	86.54	0.00e+00	1239.00
IUUC-Ame-011037	Astyanax mexicanus	71.87	0.00e+00	731.00
IUUC-Bta-012684	Bos taurus	98.80	0.00e+00	1140.00
IUUC-Bci-013875	Botrytis cinerea	27.84	6.00e-18	84.30
IUUC-Cja-019103	Callithrix jacchus	97.99	0.00e+00	1367.00
IUUC-Cfa-020670	Canis familiaris	98.38	0.00e+00	1206.00
IUUC-Cpo-021951	Cavia porcellus	98.97	0.00e+00	1143.00
IUUC-Csa-023607	Chlorocebus sabaeus	98.97	0.00e+00	1138.00
IUUC-Cho-024648	Choloepus hoffmanni	88.07	0.00e+00	1143.00
IUUC-Csv-026377	Ciona savignyi	61.30	0.00e+00	698.00
IUUC-Dre-028618	Danio rerio	73.84	0.00e+00	875.00
IUUC-Dno-029854	Dasypus novemcinctus	95.99	0.00e+00	1323.00
IUUC-Dor-030497	Dipodomys ordii	80.20	0.00e+00	992.00
IUUC-Dme-032222	Drosophila melanogaster	56.01	8.00e-176	610.00
IUUC-Ete-033156	Echinops telfairi	55.94	4.00e-148	518.00
IUUC-Eca-033525	Equus caballus	97.33	0.00e+00	1386.00
IUUC-Fca-035490	Felis catus	98.97	0.00e+00	1137.00
IUUC-Fal-037099	Ficedula albicollis	97.68	0.00e+00	1108.00
IUUC-Gmo-039532	Gadus morhua	78.00	0.00e+00	877.00
IUUC-Gga-041081	Gallus gallus	86.76	0.00e+00	1198.00
IUUC-Gac-041582	Gasterosteus aculeatus	78.18	0.00e+00	902.00
IUUC-Gma-043533	Glycine max	32.23	2.00e-38	153.00
IUUC-Ggo-044717	Gorilla gorilla	98.40	0.00e+00	1365.00
IUUC-Hsa-045726	Homo sapiens	98.40	0.00e+00	1365.00
IUUC-Hvu-047224	Hordeum vulgare	32.92	5.00e-39	155.00
IUUC-Lch-050568	Latimeria chalumnae	78.39	0.00e+00	923.00
IUUC-Lpe-051276	Leersia perrieri	27.65	3.00e-40	160.00
IUUC-Loc-052321	Lepisosteus oculatus	76.83	0.00e+00	1081.00
IUUC-Laf-054378	Loxodonta africana	96.53	0.00e+00	1339.00
IUUC-Mcc-054985	Macaca mulatta	98.13	0.00e+00	1360.00
IUUC-Mga-059582	Meleagris gallopavo	75.62	0.00e+00	918.00
IUUC-Mmr-061255	Microcebus murinus	84.55	0.00e+00	1124.00
IUUC-Mdo-062369	Monodelphis domestica	94.39	0.00e+00	1341.00
IUUC-Mmu-063334	Mus musculus	95.61	0.00e+00	1333.00
IUUC-Mpu-065886	Mustela putorius furo	75.95	0.00e+00	927.00
IUUC-Mlu-067820	Myotis lucifugus	77.46	0.00e+00	918.00
IUUC-Nle-069856	Nomascus leucogenys	98.53	0.00e+00	1367.00
IUUC-Opr-070814	Ochotona princeps	76.94	0.00e+00	881.00
IUUC-Ont-071932	Oreochromis niloticus	79.32	0.00e+00	921.00
IUUC-Oan-073455	Ornithorhynchus anatinus	77.10	0.00e+00	913.00
IUUC-Ocu-074469	Oryctolagus cuniculus	97.06	0.00e+00	1341.00
IUUC-Obr-076181	Oryza brachyantha	31.80	5.00e-36	146.00
IUUC-Ogl-077595	Oryza glaberrima	30.45	6.00e-35	142.00
IUUC-Oin-080100	Oryza indica	29.51	2.00e-34	140.00
IUUC-Olo-080536	Oryza longistaminata	31.35	1.00e-34	141.00
IUUC-Ola-087436	Oryzias latipes	78.97	0.00e+00	909.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.36	4.00e-33	134.00
IUUC-Oga-088528	Otolemur garnettii	98.06	0.00e+00	1197.00
IUUC-Oar-089603	Ovis aries	98.63	0.00e+00	1135.00
IUUC-Ptr-090657	Pan troglodytes	97.99	0.00e+00	1362.00
IUUC-Pan-092727	Papio anubis	76.92	0.00e+00	915.00
IUUC-Psi-092962	Pelodiscus sinensis	96.05	0.00e+00	1116.00
IUUC-Pma-094371	Petromyzon marinus	72.56	0.00e+00	877.00
IUUC-Pfo-096954	Poecilia formosa	64.29	0.00e+00	926.00
IUUC-Pab-097812	Pongo abelii	97.73	0.00e+00	1334.00
IUUC-Pva-103042	Pteropus vampyrus	96.72	0.00e+00	1350.00
IUUC-Rno-105085	Rattus norvegicus	76.92	0.00e+00	914.00
IUUC-Sha-107240	Sarcophilus harrisii	77.28	0.00e+00	916.00
IUUC-Sar-113739	Sorex araneus	77.48	0.00e+00	679.00
IUUC-Sbi-114612	Sorghum bicolor	29.24	4.00e-35	142.00
IUUC-Ssc-115880	Sus scrofa	99.14	0.00e+00	1141.00
IUUC-Tgu-116624	Taeniopygia guttata	94.79	0.00e+00	982.00
IUUC-Tru-117780	Takifugu rubripes	66.27	0.00e+00	917.00
IUUC-Tsy-119339	Tarsius syrichta	90.64	0.00e+00	1220.00
IUUC-Tni-120794	Tetraodon nigroviridis	76.54	0.00e+00	864.00
IUUC-Tbe-127398	Tupaia belangeri	99.69	0.00e+00	680.00
IUUC-Ttr-129024	Tursiops truncatus	96.93	0.00e+00	1389.00
IUUC-Vpa-130515	Vicugna pacos	98.63	0.00e+00	1138.00
IUUC-Vvi-131673	Vitis vinifera	33.74	1.00e-42	167.00
IUUC-Xtr-132358	Xenopus tropicalis	66.67	0.00e+00	937.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence