iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-092960

Ensembl Protein ID

ENSPSIP00000001784.1

UniProt Accession

K7F174; K7F174_PELSI

Genbank Protein ID

ENSPSIP00000001784

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01102659

Gene Name

SOCS5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000001791.1	ENSPSIT00000001791.1	ENSPSIP00000001784.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	6.30e-16	58.0	474	519

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            l r+ p+SLq++CR +I+rc++++++   d+LPLP++L+d+L++++y+
   Q: 474  SLNRTFPFSLQYICRAVICRCTTYDGI---DGLPLPSMLQDFLKEYHYK 519
           577899*********************...****************985 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MDQVGKMWNN FKYRCQNLFN HEGGNRNENT DVDSSRHSSV KDRSIHVPDL AQQQLSSPLR 60
ENIALQLGLS PSKNSAKRNQ NCVTDIPQIV EISIEKDNDT CVTGTRLARR DSYSRHAPWG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTAACATAA TCCATGGATC AAGTGGGAAA GATGTGGAAC AACTTCAAAT ACAGATGCCA 60
GAATCTCTTC AATCATGAAG GTGGAAACAG AAATGAAAAC ACAGATGTAG ACTCCAGTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR022252--SOCS4/SOCS5_dom
IPR028420--SOCS5
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0071404--P:cellular response to low-density lipoprotein particle stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007259--P:JAK-STAT cascade
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0050728--P:negative regulation of inflammatory response
GO:0032715--P:negative regulation of interleukin-6 production
GO:0071638--P:negative regulation of monocyte chemotactic protein-1 production
GO:0045629--P:negative regulation of T-helper 2 cell differentiation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045627--P:positive regulation of T-helper 1 cell differentiation
GO:0016567--P:protein ubiquitination
GO:0097699--P:vascular endothelial cell response to fluid shear stress

KEGG

pss:102454633

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000371	Aegilops tauschii	34.69	1.70e-02	32.00
IUUC-Apl-003815	Anas platyrhynchos	90.30	0.00e+00	995.00
IUUC-Aca-004504	Anolis carolinensis	83.40	0.00e+00	862.00
IUUC-Ame-010677	Astyanax mexicanus	63.16	0.00e+00	635.00
IUUC-Bta-012338	Bos taurus	89.55	0.00e+00	967.00
IUUC-Cja-019828	Callithrix jacchus	89.74	0.00e+00	954.00
IUUC-Cfa-020369	Canis familiaris	88.62	0.00e+00	965.00
IUUC-Cpo-021397	Cavia porcellus	87.50	0.00e+00	974.00
IUUC-Csa-023856	Chlorocebus sabaeus	89.37	0.00e+00	969.00
IUUC-Dre-028262	Danio rerio	62.32	6.00e-171	593.00
IUUC-Dno-029019	Dasypus novemcinctus	89.55	0.00e+00	993.00
IUUC-Dme-031965	Drosophila melanogaster	68.02	7.00e-70	258.00
IUUC-Eca-033867	Equus caballus	88.99	0.00e+00	985.00
IUUC-Fca-035806	Felis catus	89.55	0.00e+00	971.00
IUUC-Fal-037117	Ficedula albicollis	90.11	0.00e+00	984.00
IUUC-Gmo-039066	Gadus morhua	82.55	8.00e-107	380.00
IUUC-Gga-040876	Gallus gallus	90.49	0.00e+00	979.00
IUUC-Gac-042149	Gasterosteus aculeatus	65.00	0.00e+00	636.00
IUUC-Ggo-045169	Gorilla gorilla	88.62	0.00e+00	963.00
IUUC-Hsa-045805	Homo sapiens	89.74	0.00e+00	970.00
IUUC-Itr-049048	Ictidomys tridecemlineatus	88.62	0.00e+00	982.00
IUUC-Lch-049686	Latimeria chalumnae	78.29	0.00e+00	829.00
IUUC-Lpe-051639	Leersia perrieri	29.23	9.10e-02	31.60
IUUC-Loc-051745	Lepisosteus oculatus	71.38	0.00e+00	711.00
IUUC-Lma-053042	Leptosphaeria maculans	21.85	4.90e+00	28.50
IUUC-Laf-054124	Loxodonta africana	87.71	0.00e+00	968.00
IUUC-Mcc-055175	Macaca mulatta	89.37	0.00e+00	969.00
IUUC-Meu-056557	Macropus eugenii	89.42	0.00e+00	991.00
IUUC-Mga-059214	Meleagris gallopavo	89.74	0.00e+00	988.00
IUUC-Mmr-060613	Microcebus murinus	75.00	0.00e+00	747.00
IUUC-Mdo-062788	Monodelphis domestica	89.24	0.00e+00	950.00
IUUC-Mmu-064333	Mus musculus	87.50	0.00e+00	951.00
IUUC-Mpu-066048	Mustela putorius furo	89.74	0.00e+00	969.00
IUUC-Mlu-067430	Myotis lucifugus	88.99	0.00e+00	944.00
IUUC-Nle-069086	Nomascus leucogenys	89.37	0.00e+00	992.00
IUUC-Opr-070312	Ochotona princeps	86.01	0.00e+00	929.00
IUUC-Ont-072299	Oreochromis niloticus	63.52	0.00e+00	634.00
IUUC-Ocu-074123	Oryctolagus cuniculus	83.96	0.00e+00	905.00
IUUC-Ola-086934	Oryzias latipes	65.93	0.00e+00	654.00
IUUC-Oga-088535	Otolemur garnettii	89.74	0.00e+00	995.00
IUUC-Oar-089875	Ovis aries	89.74	0.00e+00	970.00
IUUC-Ptr-090541	Pan troglodytes	89.74	0.00e+00	970.00
IUUC-Pan-092416	Papio anubis	89.37	0.00e+00	969.00
IUUC-Pma-094222	Petromyzon marinus	50.45	2.00e-137	481.00
IUUC-Pfo-096930	Poecilia formosa	63.14	0.00e+00	642.00
IUUC-Pab-098659	Pongo abelii	89.55	0.00e+00	971.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.30e-01	30.80
IUUC-Pca-100222	Procavia capensis	85.47	0.00e+00	949.00
IUUC-Pva-102387	Pteropus vampyrus	89.18	0.00e+00	965.00
IUUC-Rno-105698	Rattus norvegicus	87.69	0.00e+00	953.00
IUUC-Sha-107234	Sarcophilus harrisii	88.31	0.00e+00	957.00
IUUC-Sar-113698	Sorex araneus	83.96	0.00e+00	862.00
IUUC-Ssc-115985	Sus scrofa	88.62	0.00e+00	986.00
IUUC-Tgu-116676	Taeniopygia guttata	89.74	0.00e+00	981.00
IUUC-Tru-118441	Takifugu rubripes	58.38	6.00e-152	530.00
IUUC-Tsy-119163	Tarsius syrichta	84.14	0.00e+00	923.00
IUUC-Tni-120436	Tetraodon nigroviridis	65.06	0.00e+00	640.00
IUUC-Tae-124846	Triticum aestivum	34.69	3.30e-02	31.20
IUUC-Tbe-127353	Tupaia belangeri	89.55	0.00e+00	970.00
IUUC-Ttr-128907	Tursiops truncatus	89.74	0.00e+00	953.00
IUUC-Vpa-130140	Vicugna pacos	89.74	0.00e+00	971.00
IUUC-Xtr-132817	Xenopus tropicalis	77.84	0.00e+00	847.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence