iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120829

UUCD1 version

UUC-TeN-00917

Ensembl Protein ID

ENSTNIP00000001277.1

UniProt Accession

H3BZ61; H3BZ61_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000004378.1	ENSTNIT00000000687.1	ENSTNIP00000001277.1
ENSTNIG00000004378.1	ENSTNIT00000007168.1	ENSTNIP00000007012.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-126	422.4	411	743

Active Site

Position(s)	Description	Evidence
712	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkkrl+v+f+gEegld+gGv+re+l+ll++e+ np++glf+ys ++ +tlq+npds + np+hl++F+f+Gr++g+a++++++++ 
   Q: 411  PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSI-NPDHLSYFHFVGRVMGLAVFHSHYING 498
           689*********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++++fyk+llgk+++l+dle++dpel+ksl +i+en   di+   ld tf+v+++ +g+ +++eLkp+G+n  Vt+eNk+eYv+l+v+
   Q: 499  SFTQPFYKQLLGKPIQLSDLESTDPELHKSLVWILEN---DITSV-LDHTFCVEHNAFGKLSQHELKPNGRNLAVTEENKKEYVRLYVN 583
           ***********************************99...99998.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gf+e+ip++ll+ F+++elel+i G  +id+ d+k++t+ k+ +t++s++++wFw+++e+fs+e r ++LqFv
   Q: 584  WRFMRGIEAQFLALQKGFSELIPQHLLKPFDHKELELIIGGLGKIDIADWKSNTRLKH-CTSESNVVRWFWQAVEAFSEERRGRLLQFV 671
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgs r+Pl+Gf++l+    prlf+i+  da++d+lP+++TCfn++++P Y+s+e+l+ekLl+A+eet gF +
   Q: 672  TGSTRVPLQGFKALQgsagPRLFTIHLiDANTDNLPKAHTCFNRIDVPSYESYEKLYEKLLTAVEETCGFAV 743
           ***************************99999**************************************76 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

SVLCAKNLAK KDFFRLPDPF AKVVVDGSGQ CHSTDTVKST LDPKWNQHYD LYIGKTDSIT 60
ISIWNHKKIH KRQGAGFLGC IRLLSNAISR LKDTGYQRLD LCKLNPSDSD AVRGQIVVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCAGTATTAT GTGCCAAGAA CCTCGCAAAG AAAGACTTCT TTCGTAAGTG TCTTTTTTTT 60
CCTGCATGTG TGAATACTGC TGAGACCGGG GAGTGTCTGT GTGGGCGGAC AAAAGGGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001459	Ailuropoda melanoleuca	78.96	0.00e+00	1216.00
IUUC-Bta-013221	Bos taurus	79.04	0.00e+00	1174.00
IUUC-Cho-024963	Choloepus hoffmanni	62.12	0.00e+00	760.00
IUUC-Csv-026339	Ciona savignyi	59.90	0.00e+00	907.00
IUUC-Fca-035905	Felis catus	79.68	0.00e+00	1214.00
IUUC-Fal-037336	Ficedula albicollis	80.24	0.00e+00	1222.00
IUUC-Gmo-039486	Gadus morhua	85.31	0.00e+00	900.00
IUUC-Lch-049801	Latimeria chalumnae	77.59	0.00e+00	991.00
IUUC-Laf-053644	Loxodonta africana	78.41	0.00e+00	1192.00
IUUC-Mga-059723	Meleagris gallopavo	80.64	0.00e+00	1229.00
IUUC-Mpu-065898	Mustela putorius furo	79.79	0.00e+00	1216.00
IUUC-Oan-073621	Ornithorhynchus anatinus	78.76	0.00e+00	1231.00
IUUC-Ocu-073960	Oryctolagus cuniculus	76.91	0.00e+00	1193.00
IUUC-Psi-094074	Pelodiscus sinensis	83.16	0.00e+00	945.00
IUUC-Pma-094354	Petromyzon marinus	63.94	0.00e+00	945.00
IUUC-Tsy-119455	Tarsius syrichta	76.80	0.00e+00	1136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence