iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-097685

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ankyrin repeat and SOCS box protein 11

Genbank Nucleotide ID

CR857081

Gene Name

ASB11

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000020141.1	ENSPPYT00000023489.1	ENSPPYP00000022531.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.30e-13	49.4	276	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlye 50
           ++ ll++ p+ L +LCRl++r+clg+ +++ai+kL+LP+ L ++Lly+
   Q: 276  QALLLCEGPPALSQLCRLCVRKCLGRACHQAIHKLHLPEPLERFLLYQ 323
           67789******************************************8 PP

Organism

Pongo abelii

Functional Description
(View)

May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MEDGPVFYGF KNIFITMFAT FFFFKLLIKV FLALLTHFYI VKGNRKEAAR IAEEIYGGIS 60
DCWADRSPLH EAAAQGRLLA LKTLIAQGVN VNLVTINRVS SLHEACLGGH VACAKALLEN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAGCATA AGCCAAAATG GAAGATGGTC CTGTTTTCTA TGGCTTTAAA AATATTTTTA 60
TTACAATGTT TGCTACCTTT TTTTTCTTTA AGCTTTTAAT TAAAGTTTTT TTGGCTCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001496--SOCS_box

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50225--SOCS

Pfam

PF12796--Ank_2
PF07525--SOCS_box

SMART

SM00248--ANK
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG

pon:100171419

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001489	Ailuropoda melanoleuca	93.83	6.00e-158	549.00
IUUC-Apl-003530	Anas platyrhynchos	73.99	1.00e-136	479.00
IUUC-Aca-004804	Anolis carolinensis	55.68	5.00e-81	294.00
IUUC-Ame-010976	Astyanax mexicanus	34.56	4.00e-40	158.00
IUUC-Bta-012746	Bos taurus	91.64	1.00e-159	555.00
IUUC-Cja-019292	Callithrix jacchus	98.14	7.00e-172	595.00
IUUC-Cfa-020069	Canis familiaris	94.81	6.00e-161	559.00
IUUC-Cpo-022164	Cavia porcellus	95.05	1.00e-166	578.00
IUUC-Csa-023539	Chlorocebus sabaeus	99.03	1.00e-164	572.00
IUUC-Cho-024465	Choloepus hoffmanni	75.24	7.00e-113	399.00
IUUC-Dre-028590	Danio rerio	49.08	5.00e-85	307.00
IUUC-Dno-028948	Dasypus novemcinctus	93.81	1.00e-163	568.00
IUUC-Dor-030607	Dipodomys ordii	74.92	6.00e-120	423.00
IUUC-Ete-032897	Echinops telfairi	92.21	8.00e-152	529.00
IUUC-Eca-034213	Equus caballus	97.21	4.00e-169	587.00
IUUC-Eeu-034684	Erinaceus europaeus	80.85	1.00e-110	392.00
IUUC-Fca-036195	Felis catus	87.95	7.00e-154	536.00
IUUC-Fal-037341	Ficedula albicollis	54.15	2.00e-99	355.00
IUUC-Gmo-039177	Gadus morhua	42.91	7.00e-51	193.00
IUUC-Gga-040371	Gallus gallus	73.99	3.00e-136	477.00
IUUC-Gac-041598	Gasterosteus aculeatus	46.79	8.00e-63	233.00
IUUC-Ggo-045195	Gorilla gorilla	99.38	1.00e-173	602.00
IUUC-Hsa-046101	Homo sapiens	99.38	6.00e-174	602.00
IUUC-Itr-048473	Ictidomys tridecemlineatus	97.07	1.00e-164	571.00
IUUC-Lch-049957	Latimeria chalumnae	74.47	2.00e-120	424.00
IUUC-Loc-051897	Lepisosteus oculatus	67.80	8.00e-129	452.00
IUUC-Laf-053995	Loxodonta africana	91.95	3.00e-160	557.00
IUUC-Mcc-055105	Macaca mulatta	98.71	2.00e-163	567.00
IUUC-Meu-056744	Macropus eugenii	54.62	9.00e-75	273.00
IUUC-Mga-060110	Meleagris gallopavo	74.01	2.00e-134	471.00
IUUC-Mmr-060790	Microcebus murinus	91.61	2.00e-154	538.00
IUUC-Mdo-063038	Monodelphis domestica	81.11	1.00e-145	509.00
IUUC-Mmu-063999	Mus musculus	90.40	3.00e-157	547.00
IUUC-Mpu-065750	Mustela putorius furo	92.86	3.00e-156	544.00
IUUC-Mlu-067133	Myotis lucifugus	93.19	7.00e-169	585.00
IUUC-Nle-069508	Nomascus leucogenys	99.68	1.00e-165	575.00
IUUC-Opr-070897	Ochotona princeps	69.47	6.00e-99	353.00
IUUC-Ont-072570	Oreochromis niloticus	48.30	9.00e-63	233.00
IUUC-Oan-073662	Ornithorhynchus anatinus	55.30	4.00e-81	294.00
IUUC-Ocu-074144	Oryctolagus cuniculus	96.12	6.00e-160	556.00
IUUC-Ola-086779	Oryzias latipes	51.10	8.00e-86	310.00
IUUC-Oga-088306	Otolemur garnettii	93.85	6.00e-162	563.00
IUUC-Oar-089814	Ovis aries	92.26	5.00e-160	556.00
IUUC-Ptr-091557	Pan troglodytes	90.59	3.00e-86	310.00
IUUC-Pan-092867	Papio anubis	99.35	4.00e-165	573.00
IUUC-Psi-094054	Pelodiscus sinensis	74.61	7.00e-139	486.00
IUUC-Pma-094342	Petromyzon marinus	49.44	6.00e-63	233.00
IUUC-Pfo-097132	Poecilia formosa	50.92	4.00e-90	324.00
IUUC-Pva-102949	Pteropus vampyrus	93.19	1.00e-160	558.00
IUUC-Rno-105267	Rattus norvegicus	55.68	5.00e-79	287.00
IUUC-Sha-107348	Sarcophilus harrisii	82.66	2.00e-147	514.00
IUUC-Sar-113203	Sorex araneus	64.09	2.00e-98	352.00
IUUC-Ssc-116245	Sus scrofa	92.57	9.00e-161	558.00
IUUC-Tgu-117317	Taeniopygia guttata	73.07	2.00e-135	474.00
IUUC-Tru-117578	Takifugu rubripes	49.06	1.00e-64	239.00
IUUC-Tsy-118847	Tarsius syrichta	73.07	5.00e-112	397.00
IUUC-Tni-120408	Tetraodon nigroviridis	54.21	3.00e-80	291.00
IUUC-Tme-127223	Tuber melanosporum	24.10	1.00e-06	47.80
IUUC-Tbe-127290	Tupaia belangeri	82.04	2.00e-137	481.00
IUUC-Ttr-128755	Tursiops truncatus	92.26	5.00e-161	560.00
IUUC-Vpa-130064	Vicugna pacos	85.14	3.00e-144	503.00
IUUC-Xtr-132081	Xenopus tropicalis	66.25	3.00e-121	427.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence